Brofel-N Tablet - Uses, Price, Side Effects
What is brofel-n tablet used for?
Brofel-N Tablet is a combination medicine containing Acebrophylline (100mg) and Acetylcysteine (600mg). It is used to treat respiratory conditions like chronic obstructive pulmonary disease (COPD) and asthma. Acebrophylline works as a bronchodilator to open airways, while Acetylcysteine acts as a mucolytic to thin and loosen mucus, making it easier to cough up. This helps improve breathing and reduce symptoms like wheezing and chest congestion.
- Generic Name: Acebrophylline + Acetylcysteine
- Manufacturer: Curolife Biochem Private Limited
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ brofel-n tablet Uses & Benefits
Chronic obstructive pulmonary disease (COPD), asthma, bronchitis, bronchiectasis
Off-label uses: Cystic fibrosis, Sinusitis
๐ Drug Information
| Generic Name(s) | Acebrophylline + Acetylcysteine |
| Brand Name | Ab-Flo-N Tablet |
| Manufacturer | Curolife Biochem Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Mucolytic and Bronchodilator |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Acebrophylline: bronchodilation via phosphodiesterase inhibition and adenosine antagonism; Acetylcysteine: mucolysis by breaking disulfide bonds in mucus glycoproteins
Mechanism Steps
๐ก How to Take brofel-n tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of brofel-n tablet
โ Common Side Effects
- Nausea
- Vomiting
- Heartburn
- Headache
- Dizziness
๐จ Serious Side Effects
- Bronchospasm
- Stevens-Johnson syndrome
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Hepatitis
- Nephritis
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased anticoagulant effect |
| Paracetamol | Minor | Possible increased risk of liver toxicity |
| Theophylline | Moderate | Increased theophylline levels |
๐จ Major Interactions
- Theophylline
- Warfarin
โก Moderate Interactions
- Cimetidine
- Ciprofloxacin
โน๏ธ Minor Interactions
- Alcohol
- Antacids
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
May increase risk of gastrointestinal irritation
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component, peptic ulcer, severe hepatic impairment
๐ Monitoring Parameters
Pulmonary function tests, liver function tests, renal function tests
๐คฑ Lactation Safety
Caution advised; not recommended unless clearly needed
๐ Overdose Management
Symptomatic and supportive treatment; gastric lavage if indicated
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose