brex-s syrup - Pseudoephedrine (NA) + Bromhexine (NA) medicine

brex-s syrup

4.6 (12 reviews)
๐Ÿญ Shalaks Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is brex-s syrup used for?

Brex-S Syrup (Pseudoephedrine + Bromhexine) is used to treat RESPIRATORY. It contains Pseudoephedrine (NA) + Bromhexine (NA), which Pseudoephedrine: direct and indirect sympathomimetic action on alpha-adrenergic . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Pseudoephedrine + Bromhexine
  • Manufacturer: Shalaks Healthcare
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š brex-s syrup Uses & Benefits

Symptomatic relief of nasal congestion and productive cough associated with respiratory tract infections

Off-label uses: None well-established

๐Ÿ“‹ Drug Information

Generic Name(s)Pseudoephedrine + Bromhexine
Brand NameBrex-S Syrup
ManufacturerShalaks Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassDecongestant + Mucolytic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionDistributed throughout body tissues
Protein BindingPseudoephedrine: ~20-30%; Bromhexine: ~99%
MetabolismPseudoephedrine: partially hepatic; Bromhexine: extensively hepatic
Half-LifePseudoephedrine: 4-6 hours; Bromhexine: 12 hours
ExcretionPseudoephedrine: primarily renal (70-90% unchanged); Bromhexine: renal (metabolites)
BioavailabilityPseudoephedrine: ~100%; Bromhexine: ~75-80%
Onset of ActionPseudoephedrine: 15-30 minutes; Bromhexine: 1 hour
Peak Plasma TimePseudoephedrine: 1-2 hours; Bromhexine: 1-3 hours
Duration of ActionPseudoephedrine: 4-6 hours; Bromhexine: 8-12 hours

How It Works

Pseudoephedrine: direct and indirect sympathomimetic action on alpha-adrenergic receptors causing vasoconstriction; Bromhexine: increases production of serous bronchial secretions, reduces mucus viscosity

Mechanism Steps

1Pseudoephedrine stimulates alpha-1 adrenergic receptors in nasal mucosa, causing vasoconstriction and reducing congestion.
2Bromhexine increases secretion of serous mucus in respiratory tract, reducing viscosity and facilitating expectoration.

๐Ÿ’ก How to Take brex-s syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of brex-s syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Insomnia

๐Ÿšจ Serious Side Effects

  • Hypertension
  • Tachycardia
  • Palpitations
  • Urinary retention

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Hallucinations
  • Seizures

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Hypertensive crisis
Beta-blockers Major Reduced decongestant effect, hypertension
Tricyclic antidepressants Moderate Enhanced sympathomimetic effects

๐Ÿšจ Major Interactions

  • MAOIs
  • Other sympathomimetics
  • Beta-blockers

โšก Moderate Interactions

  • Antihypertensives
  • Tricyclic antidepressants
  • Digoxin

โ„น๏ธ Minor Interactions

  • Antacids
  • Caffeine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Severe hypertension, coronary artery disease, MAOI use, hypersensitivity

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, respiratory status

๐Ÿคฑ Lactation Safety

Use with caution; pseudoephedrine excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; for pseudoephedrine: beta-blockers for tachycardia, benzodiazepines for CNS stimulation

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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