bren 200mg tablet

4.5 (14 reviews)

Ibuprofen (200mg)

🏭 Kopran Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is bren 200mg tablet used for?

Adol 200mg Tablet (Ibuprofen) is used to treat PAIN ANALGESICS. It contains Ibuprofen (200mg), which Reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzyme. Always consult your doctor before use. Take as prescribed.

Generic Name: Ibuprofen
Manufacturer: Kopran Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 bren 200mg tablet Uses & Benefits

Mild to moderate pain (headache, dental pain, dysmenorrhea, musculoskeletal pain), fever, inflammation (rheumatoid arthritis, osteoarthritis).

Off-label uses: Patent ductus arteriosus closure in neonates, Prevention of heterotopic ossification, Alzheimer's disease (investigational)

📋 Drug Information

Generic Name(s)	Ibuprofen
Brand Name	Adol 200mg Tablet
Manufacturer	Kopran Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)
Route of Administration	Oral
Storage	Store at room temperature (20-25°C) in a dry place, away from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract; peak plasma concentrations occur 1-2 hours after ingestion.

DistributionWidely distributed throughout the body; crosses the placenta and enters breast milk in low concentrations.

Protein BindingApproximately 99% bound to plasma proteins.

MetabolismPrimarily metabolized in the liver via oxidation and glucuronidation; major metabolites are inactive.

Half-Life2-4 hours

ExcretionExcreted mainly in urine as metabolites and unchanged drug (less than 10%).

Bioavailability80-100% (oral)

Onset of Action30-60 minutes

Peak Plasma Time1-2 hours

Duration of Action4-6 hours

How It Works

Reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, reducing synthesis of prostaglandins, prostacyclin, and thromboxanes.

Mechanism Steps

1Ibuprofen enters the cell and binds to the active site of COX-1 and COX-2 enzymes.

2Inhibition of COX enzymes prevents conversion of arachidonic acid to prostaglandin H2 (PGH2).

3Reduced PGH2 leads to decreased synthesis of prostaglandins, prostacyclin, and thromboxanes.

💡 How to Take bren 200mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of bren 200mg tablet

✅ Common Side Effects

Nausea
Dyspepsia
Heartburn
Diarrhea
Constipation
Headache
Dizziness
Rash

🚨 Serious Side Effects

Gastrointestinal bleeding
Peptic ulcer
Renal failure
Hypertension
Heart failure
Anaphylaxis
Stevens-Johnson syndrome

⚠️ Rare Side Effects

Aseptic meningitis
Hepatitis
Pancreatitis
Agranulocytosis
Thrombocytopenia
Visual disturbances

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Aspirin	Major	Increased risk of gastrointestinal ulceration and bleeding
Methotrexate	Major	Increased methotrexate toxicity
Lithium	Major	Increased lithium levels and toxicity
ACE inhibitors	Major	Reduced antihypertensive effect and increased risk of renal impairment
Diuretics	Moderate	Reduced diuretic effect and increased risk of renal impairment
Antihypertensives	Moderate	Reduced antihypertensive effect
SSRIs	Moderate	Increased risk of gastrointestinal bleeding
Corticosteroids	Moderate	Increased risk of gastrointestinal ulceration
Digoxin	Moderate	Increased digoxin levels
Antacids	Minor	Reduced absorption of ibuprofen
Caffeine	Minor	Additive stimulant effects
Alcohol	Minor	Increased risk of gastrointestinal irritation

🚨 Major Interactions

Aspirin
Warfarin
Methotrexate
Lithium
ACE inhibitors

⚡ Moderate Interactions

Diuretics
Antihypertensives
SSRIs
Corticosteroids
Digoxin

ℹ️ Minor Interactions

Antacids
Caffeine
Alcohol

🍽️ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

🍷 Alcohol Interaction

Increased risk of gastrointestinal bleeding and ulceration.

🛡️ Safety & Warnings

🚫 Contraindications

History of hypersensitivity to ibuprofen or other NSAIDs; active peptic ulcer disease; severe heart failure; third trimester of pregnancy; history of asthma exacerbated by NSAIDs; severe renal or hepatic impairment.

📊 Monitoring Parameters

Renal function, liver function, blood pressure, signs of gastrointestinal bleeding, and symptoms of hypersensitivity.

🤱 Lactation Safety

Compatible; small amounts excreted in breast milk, but considered safe with caution.

💊 Overdose Management

Induce emesis or gastric lavage; administer activated charcoal; supportive care; monitor for metabolic acidosis, renal failure, and gastrointestinal bleeding.

⏰ Missed Dose

Take as soon as remembered unless almost time for next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for bren 200mg tablet

View All

Alternative brands with exact same active ingredient (Ibuprofen (200mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026