Bploc R 50mg/5mg Tablet - Uses, Price, Side Effects
What is bploc r 50mg/5mg tablet used for?
Bploc R 50mg/5mg Tablet is a combination of Metoprolol Succinate (a beta blocker) and Ramipril (an ACE inhibitor). It is used to treat hypertension and heart failure by lowering blood pressure, reducing heart rate, and relaxing blood vessels. This helps prevent heart attacks, strokes, and kidney problems.
- Generic Name: Metoprolol Succinate + Ramipril
- Manufacturer: Paras Impex
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bploc r 50mg/5mg tablet Uses & Benefits
Hypertension, heart failure, post-myocardial infarction, left ventricular dysfunction
Off-label uses: Migraine prophylaxis (metoprolol), diabetic nephropathy (ramipril)
๐ Drug Information
| Generic Name(s) | Metoprolol Succinate + Ramipril |
| Brand Name | Ace Revelol 50/5 Tablet ER |
| Manufacturer | Paras Impex |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Beta-blocker + ACE inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Metoprolol: Selective beta-1 blocker reducing heart rate and contractility; Ramipril: ACE inhibitor reducing angiotensin II and aldosterone
Mechanism Steps
๐ก How to Take bploc r 50mg/5mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of bploc r 50mg/5mg tablet
โ Common Side Effects
- Fatigue
- Dizziness
- Cough
- Hypotension
- Bradycardia
- Hyperkalemia
๐จ Serious Side Effects
- Angioedema
- Severe hypotension
- Renal failure
- Hepatotoxicity
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Pancreatitis
- Pulmonary edema
- Peyronie's disease
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | Increased lithium toxicity risk |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Potassium-sparing diuretics | Major | Increased risk of hyperkalemia |
๐จ Major Interactions
- NSAIDs
- Lithium
- Potassium-sparing diuretics
- Other antihypertensives
- CYP2D6 inhibitors
โก Moderate Interactions
- Digoxin
- Clonidine
- Antidiabetic agents
- Alcohol
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
- Rifampin
๐ฝ๏ธ Food Interactions
Avoid high-fat meals with metoprolol; Ramipril absorption not significantly affected by food
๐ท Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, cardiogenic shock, decompensated heart failure, sick sinus syndrome, severe bradycardia, history of angioedema with ACE inhibitors, bilateral renal artery stenosis
๐ Monitoring Parameters
Blood pressure, heart rate, renal function, electrolytes, blood glucose
๐คฑ Lactation Safety
Metoprolol excreted in breast milk; Ramipril excreted in low amounts; use with caution
๐ Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, glucagon for beta-blocker overdose, dialysis for ramipril
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose