blockasol injection
What is blockasol injection used for?
Adhestop 25000IU Injection (Heparin) is used to treat BLOOD RELATED. It contains Heparin (5000iu/5ml), which Binds to antithrombin III, accelerating its inhibition of thrombin and factor Xa. Always consult your doctor before use. Take as prescribed.
- Generic Name: Heparin
- Manufacturer: Shree Ganesh Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ blockasol injection Uses & Benefits
Prophylaxis and treatment of venous thromboembolism (DVT, PE); treatment of acute coronary syndromes; anticoagulation during hemodialysis, cardiopulmonary bypass, and blood transfusions; initial anticoagulation in pregnancy.
Off-label uses: Anticoagulation for extracorporeal membrane oxygenation (ECMO); prevention of catheter-related thrombosis; treatment of disseminated intravascular coagulation (DIC).
๐ Drug Information
| Generic Name(s) | Heparin |
| Brand Name | Adhestop 25000IU Injection |
| Manufacturer | Shree Ganesh Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Unfractionated Heparin (UFH) |
| Route of Administration | Intravenous (IV) or subcutaneous (SC); not for intramuscular use. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from freezing; do not use if discolored or contains precipitate. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to antithrombin III, accelerating its inhibition of thrombin and factor Xa.
Mechanism Steps
๐ก How to Take blockasol injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of blockasol injection
โ Common Side Effects
- Bleeding
- Pain at injection site
- Bruising
- Hematoma
- Thrombocytopenia (mild)
๐จ Serious Side Effects
- Heparin-induced thrombocytopenia (HIT)
- Major hemorrhage
- Spinal hematoma (with neuraxial anesthesia)
- Osteoporosis (long-term use)
- Hypersensitivity reactions
- Skin necrosis
โ ๏ธ Rare Side Effects
- Aldosterone suppression (hyperkalemia)
- Priapism
- Rebound hyperlipidemia
- Alopecia
- Delayed hypersensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased bleeding risk |
| NSAIDs | Major | Increased bleeding risk |
| Clopidogrel | Major | Increased bleeding risk |
| Dabigatran | Major | Increased bleeding risk |
| Rivaroxaban | Major | Increased bleeding risk |
| Apixaban | Major | Increased bleeding risk |
| Edoxaban | Major | Increased bleeding risk |
| Fondaparinux | Major | Increased bleeding risk |
| Thrombolytics | Major | Increased bleeding risk |
| Corticosteroids | Moderate | Increased bleeding risk |
| Estrogens | Moderate | Reduced anticoagulant effect |
| Progestins | Moderate | Reduced anticoagulant effect |
| Antiplatelet drugs | Moderate | Increased bleeding risk |
| SSRIs | Moderate | Increased bleeding risk |
| SNRIs | Moderate | Increased bleeding risk |
| Valproic acid | Moderate | Increased bleeding risk |
| Cephalosporins | Moderate | Increased bleeding risk |
| Penicillins | Moderate | Increased bleeding risk |
| Digoxin | Minor | Possible reduced digoxin effect |
| Quinidine | Minor | Possible reduced quinidine effect |
| Tetracyclines | Minor | Possible reduced anticoagulant effect |
| Antihistamines | Minor | Possible reduced anticoagulant effect |
| Vitamin K | Minor | Antagonizes anticoagulant effect |
๐จ Major Interactions
- Warfarin
- Aspirin
- NSAIDs
- Clopidogrel
- Dabigatran
- Rivaroxaban
- Apixaban
- Edoxaban
- Fondaparinux
- Thrombolytics
โก Moderate Interactions
- Corticosteroids
- Estrogens
- Progestins
- Antiplatelet drugs
- SSRIs
- SNRIs
- Valproic acid
- Cephalosporins
- Penicillins
โน๏ธ Minor Interactions
- Digoxin
- Quinidine
- Tetracyclines
- Antihistamines
- Vitamin K
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May increase bleeding risk; avoid excessive alcohol consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to heparin; history of heparin-induced thrombocytopenia (HIT); active bleeding; severe thrombocytopenia; uncontrolled bleeding disorders; recent surgery of eye, brain, or spinal cord; epidural or spinal anesthesia (risk of spinal hematoma).
๐ Monitoring Parameters
aPTT (target 1.5-2.5 times control); platelet count (monitor for HIT); signs of bleeding; renal function.
๐คฑ Lactation Safety
Not excreted in breast milk; considered compatible with breastfeeding.
๐ Overdose Management
Discontinue heparin; administer protamine sulfate (1 mg per 100 units of heparin given in last 4 hours); monitor aPTT and bleeding.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose; consult physician.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.