Bitmet AM 5mg/50mg Tablet - Uses, Price, Side Effects
What is bitmet am 5mg/50mg tablet used for?
Bitmet AM 5mg/50mg Tablet is a combination of Amlodipine (a calcium channel blocker) and Metoprolol Succinate (a beta blocker). It is used to treat hypertension and angina by relaxing blood vessels and reducing heart rate, thereby lowering blood pressure and improving blood flow.
- Generic Name: Amlodipine + Metoprolol Succinate
- Manufacturer: Elicad Pharmacueticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bitmet am 5mg/50mg tablet Uses & Benefits
Hypertension, stable angina, chronic heart failure (metoprolol).
Off-label uses: Migraine prophylaxis (metoprolol), Raynaud's phenomenon (amlodipine).
๐ Drug Information
| Generic Name(s) | Amlodipine + Metoprolol Succinate |
| Brand Name | Amtas-M 50 Tablet PR |
| Manufacturer | Elicad Pharmacueticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Calcium channel blocker + Beta-blocker) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amlodipine inhibits calcium influx across cell membranes, causing vasodilation; Metoprolol selectively blocks beta-1 adrenergic receptors, reducing heart rate and contractility.
Mechanism Steps
๐ก How to Take bitmet am 5mg/50mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of bitmet am 5mg/50mg tablet
โ Common Side Effects
- Edema
- Dizziness
- Fatigue
- Headache
- Nausea
- Bradycardia
๐จ Serious Side Effects
- Heart block
- Severe hypotension
- Bronchospasm
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Leukopenia
- Thrombocytopenia
- Stevens-Johnson syndrome
- Pulmonary fibrosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Digoxin | Moderate | Increased bradycardia risk |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP2D6 inhibitors (e.g., fluoxetine)
- Beta-blockers (additive bradycardia)
- Calcium channel blockers (additive hypotension)
โก Moderate Interactions
- NSAIDs
- Digoxin
- Clonidine
- Cimetidine
โน๏ธ Minor Interactions
- Grapefruit juice (amlodipine)
- Antacids
- Rifampin
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase amlodipine levels; avoid high-fat meals with metoprolol.
๐ท Alcohol Interaction
May enhance hypotensive effects; avoid excessive alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, cardiogenic shock, severe bradycardia, heart block, sick sinus syndrome, uncontrolled heart failure, severe hypotension.
๐ Monitoring Parameters
Blood pressure, heart rate, ECG, renal function, liver enzymes.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for amlodipine overdose.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.