biotram pd tablet - Uses, Price, Side Effects & Substitutes
What is biotram pd tablet used for?
Actidol-DP Tablet (Domperidone + Paracetamol) is used to treat PAIN ANALGESICS. It contains Domperidone (10mg) + Paracetamol (500mg), which Domperidone: Dopamine D2 receptor antagonist in CTZ and GI tract; Paracetamol: C. Always consult your doctor before use. Take as prescribed.
- Generic Name: Domperidone + Paracetamol
- Manufacturer: Supermax Laboratories
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ biotram pd tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Domperidone + Paracetamol |
| Brand Name | Actidol-DP Tablet |
| Manufacturer | Supermax Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Pain Analgesics |
| Route of Administration | Oral |
| Storage | Store below 30ยฐC, protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Domperidone: Dopamine D2 receptor antagonist in CTZ and GI tract; Paracetamol: COX inhibition in CNS, possibly via COX-3.
Mechanism Steps
๐ก How to Take biotram pd tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biotram pd tablet
โ Common Side Effects
- Dry mouth
- Drowsiness
- Nausea
- Headache
๐จ Serious Side Effects
- QT prolongation
- Tardive dyskinesia
- Hepatotoxicity
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Thrombocytopenia
- Galactorrhea
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ketoconazole | Major | Increased domperidone levels, QT prolongation risk |
| Alcohol | Moderate | Increased hepatotoxicity risk |
๐จ Major Interactions
- MAOIs
- CYP3A4 inhibitors (e.g., ketoconazole)
- Warfarin
โก Moderate Interactions
- Anticholinergics
- Opioids
- Alcohol
โน๏ธ Minor Interactions
- Antacids
- H2 blockers
๐ฝ๏ธ Food Interactions
Food delays absorption of domperidone; paracetamol absorption may be delayed by high-carb meals.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity with paracetamol; domperidone may enhance CNS depression.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, GI hemorrhage, prolactinoma, severe hepatic impairment.
๐ Monitoring Parameters
Liver function, ECG (QT interval), renal function.
๐คฑ Lactation Safety
Domperidone excreted in milk; paracetamol safe in usual doses.
๐ Overdose Management
Paracetamol: N-acetylcysteine; Domperidone: Supportive care, ECG monitoring.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose.