biorubin 50mg injection
What is biorubin 50mg injection used for?
Alrubicin (Epirubicin) is used to treat ANTI NEOPLASTICS. It contains Epirubicin (50mg), which Intercalates between DNA base pairs, inhibits topoisomerase II, and generates fr. Always consult your doctor before use. Take as prescribed.
- Generic Name: Epirubicin
- Manufacturer: Biochem Pharmaceutical Industries
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ biorubin 50mg injection Uses & Benefits
Breast cancer, ovarian cancer, gastric cancer, lung cancer, lymphomas, leukemias.
Off-label uses: Bladder cancer, soft tissue sarcoma, multiple myeloma.
๐ Drug Information
| Generic Name(s) | Epirubicin |
| Brand Name | Alrubicin |
| Manufacturer | Biochem Pharmaceutical Industries |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous |
| Storage | Store at 2-8ยฐC, protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Intercalates between DNA base pairs, inhibits topoisomerase II, and generates free radicals leading to DNA damage and cell death.
Mechanism Steps
๐ก How to Take biorubin 50mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of biorubin 50mg injection
โ Common Side Effects
- Nausea
- vomiting
- alopecia
- myelosuppression
- mucositis
- fatigue
๐จ Serious Side Effects
- Cardiotoxicity
- secondary leukemia
- severe myelosuppression
- hepatotoxicity
- tumor lysis syndrome
โ ๏ธ Rare Side Effects
- Anaphylaxis
- radiation recall
- extravasation necrosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Trastuzumab | Major | Increased risk of cardiotoxicity |
| Cyclophosphamide | Major | Increased risk of hemorrhagic cystitis and cardiotoxicity |
| Paclitaxel | Major | Increased myelosuppression |
| Doxorubicin | Major | Additive cardiotoxicity |
| Verapamil | Moderate | Increased epirubicin levels |
| Cimetidine | Moderate | Decreased clearance of epirubicin |
| Phenobarbital | Moderate | Increased metabolism of epirubicin |
| Dexamethasone | Minor | Possible minor interaction |
| Metoclopramide | Minor | Possible minor interaction |
๐จ Major Interactions
- Trastuzumab
- Cyclophosphamide
- Paclitaxel
- Doxorubicin
โก Moderate Interactions
- Verapamil
- Cimetidine
- Phenobarbital
โน๏ธ Minor Interactions
- Dexamethasone
- Metoclopramide
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May increase hepatotoxicity risk; avoid alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to epirubicin, severe hepatic impairment, severe myocardial insufficiency, recent myocardial infarction, severe arrhythmias, previous treatment with maximum cumulative doses of anthracyclines.
๐ Monitoring Parameters
CBC, liver function tests, renal function, cardiac function (LVEF), ECG.
๐คฑ Lactation Safety
Contraindicated; discontinue nursing.
๐ Overdose Management
Supportive care, monitor for myelosuppression and cardiotoxicity; no specific antidote.
โฐ Missed Dose
Do not double dose; consult physician.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for biorubin 50mg injection
View AllAlternative brands with exact same active ingredient (Epirubicin (50mg)):
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anthracin 50mg injectionDabur India Ltd โน60.89 93.2% CHEAPER
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erubin 50mg injectionRPG Life Sciences Ltd โน597.00 33.7% CHEAPER
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epineon 50mg injectionNeon Laboratories Ltd โน637.63 29.2% CHEAPER
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innorubicin 50mg injectionInnova Formulations Pvt Ltd โน931.83 3.4% COSTLIER
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epitero 50 injectionHetero Drugs Ltd โน978.00 8.6% COSTLIER
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epichlor 50 injectionKhandelwal Laboratories Pvt Ltd โน1,056.00 17.2% COSTLIER
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epicure 50mg injectionEmcure Pharmaceuticals Ltd โน1,113.00 23.5% COSTLIER
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epidox 50mg injectionSamarth Life Sciences Pvt Ltd โน1,171.36 30% COSTLIER
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alrubicin 50mg injectionAlkem Laboratories Ltd โน1,182.00 31.2% COSTLIER
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zuvicin 50mg injectionZuventus Healthcare Ltd โน1,298.00 44.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.