Candiforce 100 Capsule (Itraconazole 100mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Yellowing of the eyes or skin, dark urine, or pale stools
- Swelling of the feet or legs, sudden weight gain, or shortness of breath
- Severe skin rash with blisters or peeling
- Numbness, tingling, or burning in hands or feet
- Hearing loss or ringing in the ears
- Severe abdominal pain or persistent vomiting
- Chest pain or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is bioitra 100mg capsule used for?
This medicine is an oral antifungal capsule containing 100 mg itraconazole. It treats fungal infections of the skin, nails, mouth, and internal organs by breaking down the fungal cell membrane. It must be taken with food and is available only by prescription.
- Generic Name: Itraconazole
- Manufacturer: Bionexa Organic
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 bioitra 100mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा इट्राकोनाज़ोल 100 मिलीग्राम कैप्सूल है, जिसका उपयोग फंगल संक्रमण के इलाज के लिए किया जाता है। यह त्वचा, नाखून, मुँह और शरीर के अंदरूनी अंगों में होने वाले फंगल संक्रमणों के लिए प्रभावी है। यह दवा फंगस की कोशिका झिल्ली को तोड़कर उसे मार देती है। इसे हमेशा भोजन के साथ लेना चाहिए क्योंकि इससे दवा का अवशोषण बेहतर होता है। यह डॉक्टर के पर्चे पर ही मिलती है और बिना डॉक्टर की सलाह के नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, पेट दर्द, सिरदर्द और हल्के दाने शामिल हैं। कभी-कभी यह लिवर को नुकसान पहुंचा सकती है, दिल की विफलता को बढ़ा सकती है, या सुनने की क्षमता को प्रभावित कर सकती है। अगर आपको पैरों में सूजन, सांस लेने में तकलीफ, आँखों या त्वचा का पीलापन, या गंभीर दाने दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें। डॉक्टर की सलाह के बिना दवा शुरू या बंद न करें। अगर आपको दिल, लिवर या किडनी की समस्या है तो डॉक्टर को बताएं। इस दवा के साथ अंगूर या अंगूर का जूस न लें। एंटासिड या पेट की एसिड कम करने वाली दवाएं इस दवा से 2 घंटे पहले या बाद में लें। अगर आपको चक्कर आएं या सुनने में बदलाव हो तो गाड़ी न चलाएं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
💊 bioitra 100mg capsule Uses & Benefits
[{"condition":"Dermatophyte skin infections (tinea corporis, tinea cruris, tinea pedis)","description":"Used to treat fungal infections of the skin caused by dermatophytes when topical treatment is not suitable or has failed.","evidence":"Well-established"},{"condition":"Onychomycosis (fungal nail infection)","description":"Prescribed as pulse therapy or continuous therapy for toenail and fingernail fungal infections.","evidence":"Well-established"},{"condition":"Oral and oesophageal candidiasis","description":"Used for oropharyngeal and oesophageal candidiasis, especially in immunocompromised patients.","evidence":"Well-established"},{"condition":"Systemic mycoses (histoplasmosis, blastomycosis, aspergillosis)","description":"Used in the treatment of certain deep fungal infections in immunocompromised or non-immunocompromised patients.","evidence":"Established for specific indications"},{"condition":"Pityriasis versicolor","description":"Used for extensive or recurrent pityriasis versicolor when topical agents are inadequate.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Seborrheic dermatitis","description":"Sometimes used off-label for severe or refractory seborrheic dermatitis due to Malassezia species.","evidence":"Limited"},{"condition":"Fungal keratitis (adjunct)","description":"Occasionally used as an adjunct in difficult fungal eye infections under specialist care.","evidence":"Limited"}]
Primary treatment for: Fungal infections
Also treats: Dermatophytosis, Onychomycosis, Candidiasis, Histoplasmosis, Aspergillosis
📋 Drug Information
| Generic Name(s) | Itraconazole |
| Brand Name | Alcros 100 Capsule |
| Manufacturer | Bionexa Organic |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively inhibiting the fungal cytochrome P450 enzyme lanosterol 14-alpha-demethylase, which is responsible for converting lanosterol to ergosterol. Ergosterol is a critical component of the fungal cell membrane. When ergosterol production is blocked, the fungal cell membrane becomes defective, leading to increased permeability and leakage of cellular contents. This stops fungal growth and allows the body's immune system to clear the infection. Because the target enzyme is specific to fungi, human cells are less affected, but itraconazole can still interact with human cytochrome P450 enzymes, especially CYP3A4.
Mechanism Steps
💡 How to Take bioitra 100mg capsule
Strength: Capsule, 100 mg
Dosage Information
| Adult Dosage | The dose of this medicine depends on the type and severity of the fungal infection. For skin infections, a common dose is 100 mg to 200 mg once daily for 1 to 4 weeks. For nail infections, pulse therapy with 200 mg twice daily for 1 week per month for 2 to 3 months may be used. For systemic mycoses, higher doses may be needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially heart and liver effects. Dose should be individualized by a qualified clinician based on renal and hepatic function and concomitant medicines. |
| Renal Impairment | Dose adjustment may be needed in patients with severe kidney impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | This medicine should be used with caution in patients with liver disease. Dose adjustment may be necessary. Regular monitoring of liver function is recommended. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose depends on the indication and is determined by a qualified clinician. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of bioitra 100mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cisapride | Major | |
| Midazolam | Major | |
| Simvastatin | Major | |
| Warfarin | Major | |
| Ergotamine | Major | |
| Phenytoin | Moderate | |
| Omeprazole | Moderate | |
| Nifedipine | Moderate | |
| Glibenclamide | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Cisapride, pimozide, quinidine, dofetilide
- Midazolam, triazolam
- HMG-CoA reductase inhibitors (statins) metabolized by CYP3A4 (e.g., simvastatin, lovastatin)
- Ergot alkaloids (e.g., ergotamine, dihydroergotamine)
- Warfarin
⚡ Moderate Interactions
- Phenytoin, carbamazepine, rifampicin
- Proton pump inhibitors (e.g., omeprazole)
- Calcium channel blockers (e.g., nifedipine, amlodipine)
- Oral hypoglycemics (e.g., glibenclamide)
🍷 Alcohol Interaction
Alcohol may increase the risk of liver problems and stomach upset when taken with this medicine. It is best to avoid alcohol while taking this medicine, especially if you have any liver concerns.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to itraconazole or other azole antifungals","History of heart failure or ventricular dysfunction","Concurrent use with cisapride, pimozide, quinidine, dofetilide, or levomethadyl","Concurrent use with ergot alkaloids (e.g., ergotamine, dihydroergotamine)","Concurrent use with certain statins (simvastatin, lovastatin)","Pregnancy (especially first trimester) unless clearly needed","Severe liver disease"]
⚠️ Warnings & Precautions
["Take this medicine with a full meal to ensure proper absorption.","Do not take with antacids or acid reducers within 2 hours.","Avoid grapefruit and grapefruit juice.","Inform your doctor if you have heart, liver, or kidney problems.","This medicine can interact with many other medicines; always provide a complete list of medicines to your doctor.","Do not drive or operate machinery if you feel dizzy or have hearing changes.","Report any signs of liver problems, heart failure, or severe skin reactions immediately."]
🤱 Lactation Safety
This medicine is excreted in breast milk in small amounts. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
There is no specific antidote for an overdose of this medicine. In case of overdose, stop the medicine and seek immediate medical attention. Treatment should be supportive and symptomatic. Contact a poison control center or emergency department for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is more than 12 hours before your next scheduled dose. If it is less than 12 hours before your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine with a full meal to improve absorption and reduce stomach upset. Do not start, stop, or change the dose without talking to your doctor. Tell your doctor if you have heart failure, liver problems, or kidney problems before taking this medicine. Avoid grapefruit and grapefruit juice while on this medicine. Do not take antacids, acid reducers, or stomach acid suppressants within 2 hours of this medicine unless your doctor approves. Report any swelling of the feet or legs, shortness of breath, yellowing of the eyes or skin, dark urine, or unusual tiredness immediately. This medicine can make you dizzy or affect your hearing; avoid driving or operating machinery if you feel unwell. Do not share this medicine with anyone else.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially heart and liver effects. Dose should be individualized by a qualified clinician based on renal and hepatic function and concomitant medicines. Regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. This medicine should be used during pregnancy only if clearly needed. Use effective contraception while taking this medicine and for a period after stopping, as advised by your doctor.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with other medicines used during surgery. Your doctor may advise you to stop the medicine temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine can interact with certain medicines used in dentistry, and it may affect healing. Your dentist may coordinate with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or hearing changes in some people. Avoid strenuous exercise or activities that require alertness if you feel unwell. Consult your doctor before starting any new exercise routine while on this medicine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, headache, or hearing changes in some people. If you experience these effects, avoid driving or operating heavy machinery. Most people can continue their normal daily activities, but listen to your body and rest if needed. Inform your employer if your work requires alertness and you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can allow the infection to return. Your doctor will tell you when to stop based on your condition and response to treatment. If you experience serious side effects, stop the medicine and seek medical attention immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of liver injury, heart failure, and peripheral neuropathy. Regular monitoring of liver function and heart health is recommended for patients on prolonged therapy. If you notice any unusual symptoms, report them to your doctor promptly. The medicine may also accumulate in the body, so your doctor may adjust the dose or duration based on your response.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild skin fungal infections, topical creams may be sufficient and have fewer side effects.
Evidence: Well-establishedAn alternative oral antifungal for skin and nail infections, with a different interaction profile.
Evidence: Well-establishedKeeping skin dry, wearing breathable clothing, and avoiding sharing personal items can help prevent fungal infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not directly interact with vaccines. However, if you have a fungal infection, your immune system may be compromised, and your doctor may advise on appropriate vaccinations. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. Store at room temperature and protect from light and moisture. If crossing time zones, continue taking it at the same interval as prescribed, but consult your doctor for specific advice. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For skin infections, improvement may be seen within 1 to 2 weeks. For nail infections, it may take several weeks to months to see clear growth.
A: Yes, this medicine should be taken with a full meal to improve absorption and reduce stomach upset.
A: If you remember within 12 hours of the missed dose, take it as soon as possible. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor immediately if you are pregnant or planning to become pregnant.
A: It is best to avoid alcohol while taking this medicine because it may increase the risk of liver problems and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for bioitra 100mg capsule
View AllAlternative brands with exact same active ingredient:
-
fungizee 100mg capsuleZeelab Pharmacy Pvt Ltd ₹20.00 78.9% CHEAPER
-
davaindia itraconazole 100mg capsuleDavaindia Generic Pharmacy ₹22.50 76.2% CHEAPER
-
fungiforce -itra 100 capsuleMankind Pharma Ltd ₹29.30 69% CHEAPER
-
itraks 100mg capsuleAxis Life Science Pvt Ltd ₹31.25 67% CHEAPER
-
itrafort 100 capsuleDabur India Ltd ₹33.75 64.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without food.
Fact: This medicine should be taken with a full meal because food improves its absorption. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for people with heart failure or certain liver conditions and has many drug interactions.
🔄 Alternative Options
Generic Alternatives
- Itraconazole 100 mg capsule
Brand Alternatives
- Candiforce 100 capsule