biogesic 50mg tablet - Nimesulide (50mg) medicine

Biogesic 50mg Tablet - Uses, Price, Side Effects

4.5 (12 reviews)

Nimesulide (50mg)

🏭 Biochem Pharmaceutical Industries 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is biogesic 50mg tablet used for?

Biogesic 50mg Tablet contains Nimesulide, a non-steroidal anti-inflammatory drug (NSAID) used to relieve acute pain and fever. It works by inhibiting prostaglandin synthesis, reducing inflammation and pain. It is typically taken twice daily after meals. Consult your doctor for proper dosage.

Generic Name: Nimesulide
Manufacturer: Biochem Pharmaceutical Industries
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 biogesic 50mg tablet Uses & Benefits

Acute pain, dysmenorrhea, postoperative pain, musculoskeletal disorders, fever.

Off-label uses: Not commonly used off-label due to safety concerns.

📋 Drug Information

Generic Name(s)	Nimesulide
Brand Name	Aulin 100mg Tablet
Manufacturer	Biochem Pharmaceutical Industries
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	NSAID's-Non-Selective COX 1&2 Inhibitors (Others)
Route of Administration	Oral
Storage	Store at room temperature (15-30°C), protect from moisture and light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration, with peak plasma concentrations achieved within 1-3 hours.

DistributionExtensively distributed to tissues; crosses the placenta and enters breast milk.

Protein Binding>97.5% bound to plasma proteins, primarily albumin.

MetabolismExtensively metabolized in the liver via CYP2C9 and other pathways; major metabolite is 4-hydroxynimesulide.

Half-LifeApproximately 1.8-4.7 hours.

ExcretionPrimarily renal (about 50-60% as metabolites, <1% unchanged); also biliary excretion.

BioavailabilityApproximately 100% after oral administration.

Onset of ActionWithin 15-30 minutes.

Peak Plasma Time1-3 hours.

Duration of Action6-8 hours.

How It Works

Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthesis.

Mechanism Steps

1Inhibition of COX-2 enzyme

2Reduction of prostaglandin synthesis from arachidonic acid

3Decreased inflammation, pain, and fever

💡 How to Take biogesic 50mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of biogesic 50mg tablet

✅ Common Side Effects

Nausea
Dyspepsia
Diarrhea
Headache
Dizziness
Rash

🚨 Serious Side Effects

Hepatotoxicity
Gastrointestinal bleeding
Stevens-Johnson syndrome
Acute renal failure
Anaphylaxis

⚠️ Rare Side Effects

Thrombocytopenia
Agranulocytosis
Pancreatitis
Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Aspirin	Moderate	Increased risk of gastrointestinal ulceration
Lithium	Moderate	Increased lithium levels and toxicity

🚨 Major Interactions

Warfarin
Aspirin
Methotrexate
Lithium
Anticoagulants

⚡ Moderate Interactions

ACE inhibitors
Diuretics
Corticosteroids
Antiplatelet agents

ℹ️ Minor Interactions

Antacids
Cimetidine

🍽️ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

🍷 Alcohol Interaction

Increased risk of gastrointestinal bleeding and hepatotoxicity.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Moderate

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to nimesulide or NSAIDs, active peptic ulcer, severe hepatic impairment, severe renal impairment, pregnancy (third trimester), lactation, children <12 years.

📊 Monitoring Parameters

Liver function tests, renal function, blood pressure, signs of GI bleeding.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for biogesic 50mg tablet

View All

Alternative brands with exact same active ingredient (Nimesulide (50mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026