biocetamol 150mg injection - Paracetamol (150mg) medicine

Aeknil Injection: Complete Medicine Guide

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🏭 Biochem Pharmaceutical Industries 📦 Varies by brand 💊 Allopathy 📅 Updated: Nov 1, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for pain and fever.
Reviewed by
SaathiMed Expert Panel | Nov 01, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes
  • Severe abdominal pain
  • Dark urine
  • Difficulty breathing
  • Swelling of face, lips, or throat
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is biocetamol 150mg injection used for?

This medicine is a paracetamol injection used for rapid relief of mild to moderate pain and fever when oral administration is not possible. It works by blocking pain signals and lowering fever.

  • Generic Name: Paracetamol
  • Manufacturer: Biochem Pharmaceutical Industries
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 biocetamol 150mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल का इंजेक्शन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार को कम करने के लिए किया जाता है। यह उन रोगियों के लिए उपयोगी है जो मुंह से दवा नहीं ले सकते। यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी और इंजेक्शन स्थल पर दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन त्वचा पर गंभीर प्रतिक्रियाएं, यकृत की क्षति और एलर्जी प्रतिक्रियाएं हो सकती हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल स्वास्थ्यकर्मी द्वारा दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। यदि आपको यकृत या गुर्दे की समस्या है या पैरासिटामोल से एलर्जी है, तो डॉक्टर को बताएं। इस दवा के साथ शराब का सेवन न करें। निर्धारित खुराक से अधिक न लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 biocetamol 150mg injection Uses & Benefits

[{"condition":"Mild to moderate pain","description":"Relieves pain such as headache, muscle ache, and postoperative pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces elevated body temperature.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Pain and fever

Also treats: Headache, Muscle ache, Postoperative pain

📋 Drug Information

Generic Name(s)Paracetamol
Brand NameAction or 1000mg Tablet
ManufacturerBiochem Pharmaceutical Industries
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAnalgesic & Antipyretic-PCM
Route of AdministrationParenteral (intramuscular or intravenous)
StorageStore at room temperature (15-30°C). Protect from light and moisture. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineParacetamol is included in the WHO Model List of Essential Medicines for the treatment of pain and fever.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only when oral paracetamol is not feasible.
2
Always check the total daily dose from all sources to avoid hepatotoxicity.
3
Use with caution in patients with liver disease or chronic alcohol use.
4
Monitor liver function in patients receiving long-term therapy.
5
Inform patients about the signs of allergic reactions and when to seek help.
6
Rotate injection sites to minimize local pain.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Mild to moderate pain
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
This medicine is used to reduce fever.
Likely Use
❌
Severe pain requiring opioids
This medicine may not be sufficient for severe pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular administration, paracetamol is rapidly and completely absorbed. The bioavailability is high, approximately 80-100%. After intravenous administration, bioavailability is 100%.
DistributionParacetamol is distributed widely throughout most body tissues. It crosses the placenta and is excreted in breast milk. The volume of distribution is approximately 0.8-1.0 L/kg.
Protein BindingParacetamol is minimally bound to plasma proteins (approximately 10-25%).
MetabolismParacetamol is primarily metabolized in the liver via glucuronidation and sulfation. A small fraction is metabolized by cytochrome P450 2E1 to a toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), which is normally detoxified by glutathione.
Half-LifeThe elimination half-life of paracetamol is approximately 2-3 hours in adults with normal liver function. It may be prolonged in patients with liver disease or after overdose.
ExcretionParacetamol is excreted in the urine as glucuronide and sulfate conjugates. Less than 5% is excreted unchanged.
BioavailabilityApproximately 80-100% following intramuscular administration; 100% following intravenous administration.
Onset of ActionPain relief begins within 5-10 minutes after intravenous administration and within 10-30 minutes after intramuscular administration. Fever reduction begins within 30 minutes.
Peak Plasma TimePeak plasma concentration is reached within 15-30 minutes after intramuscular administration and immediately after intravenous administration.
Duration of ActionThe analgesic and antipyretic effects last for approximately 4-6 hours.

How It Works

This medicine works primarily in the central nervous system. It increases the pain threshold by inhibiting prostaglandin synthesis in the brain and spinal cord. It also acts on the hypothalamic heat-regulating center to produce peripheral vasodilation, which leads to sweating and dissipation of heat, thereby reducing fever.

Mechanism Steps

1
Inhibition of prostaglandin synthesis: This medicine inhibits the enzyme cyclooxygenase (COX) in the central nervous system, leading to decreased production of prostaglandins, which are mediators of pain and fever.
2
Activation of descending inhibitory pathways: This medicine may activate descending serotonergic pathways that inhibit pain transmission in the spinal cord.
3
Effect on hypothalamic set-point: This medicine acts on the hypothalamus to reset the body's temperature set-point, resulting in vasodilation and sweating, which lowers body temperature.

💡 How to Take biocetamol 150mg injection

Strength: Injection: 150mg per dose

1This medicine is administered by a healthcare professional.
2It is given as an intramuscular or intravenous injection.
3The injection site should be rotated to prevent pain.
4Do not self-administer.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 150mg to 1000mg every 4 to 6 hours as needed, administered intramuscularly or intravenously. The maximum daily dose is 4000mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced hepatic and renal function. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance <30 mL/min), the dosing interval should be increased to every 6-8 hours. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with hepatic impairment, the dose should be reduced or the dosing interval increased. The maximum daily dose should not exceed 2 grams. Dose must be individualized by a qualified clinician.
Maximum Daily Dose4000mg per day for adults. In patients with liver disease or chronic alcohol use, the maximum daily dose is 2000mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing required
This medicine is given as an injection, so food timing does not affect it.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of biocetamol 150mg injection

✅ Common Side Effects

Nausea (Common (1-10%))
Usually resolves on its own. If persistent, consult your doctor.
Vomiting (Common (1-10%))
Stay hydrated. If vomiting continues, seek medical advice.
Injection site pain (Common (1-10%))
Apply a cold compress to the site. Report if severe or persistent.

🚨 Serious Side Effects

Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Seek immediate medical attention if you notice rash, blistering, or peeling skin.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you experience yellowing of skin or eyes, dark urine, or severe abdominal pain.
Anaphylaxis (Very rare (<0.01%))
Call emergency services immediately if you experience difficulty breathing, swelling of face, lips, or throat, or a severe rash.

⚠️ Rare Side Effects

Thrombocytopenia
Report any unusual bleeding or bruising to your doctor.
Leukopenia
Report any signs of infection such as fever, sore throat, or fatigue.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Carbamazepine Moderate
Phenytoin Moderate
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Carbamazepine
  • Phenytoin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it increases the risk of liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe liver disease","Hypersensitivity to paracetamol","Severe renal impairment"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose.","Avoid alcohol during treatment.","Use with caution in patients with liver or kidney disease.","Consult a doctor before use in pregnancy or breastfeeding.","Do not use for more than 3 days without medical advice."]

🤱 Lactation Safety

Paracetamol is excreted in breast milk in small amounts. It is considered safe for use during breastfeeding. Consult your doctor before use.

💊 Overdose Management

Overdose of paracetamol can cause severe liver damage. Symptoms of overdose may include nausea, vomiting, abdominal pain, and confusion. If overdose is suspected, seek immediate medical attention. The antidote is N-acetylcysteine, which should be administered as soon as possible.

⏰ Missed Dose

Since this medicine is usually administered by a healthcare professional, missed doses are unlikely. If you miss a dose, contact your healthcare provider for guidance. Do not double the dose to catch up.

Additional Safety Advice

General Safety

This medicine should only be administered by a healthcare professional. Do not self-administer. Inform your doctor if you have liver or kidney problems, or if you are allergic to paracetamol. Avoid alcohol while receiving this medicine. Do not exceed the recommended dose. If you experience signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the side effects of this medicine, especially liver and kidney toxicity. Lower doses may be required. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

Paracetamol is considered safe during pregnancy when used at recommended doses. Consult your doctor before use if you are planning pregnancy or are pregnant.

🏥 Post-Surgery Considerations

This medicine is often used for postoperative pain relief. It is effective for mild to moderate pain and can be combined with other analgesics as prescribed.

🦷 Dental Procedures

This medicine can be used for pain relief after dental procedures. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated.
🥗
Avoid alcohol consumption.
😴
Maintain a healthy diet.
💧
Get adequate rest.
🧘
Follow up with your doctor regularly.

🏋️ Exercise Considerations

No specific exercise restrictions are associated with this medicine. However, if you are receiving it for pain, avoid strenuous activities until the pain subsides.

🥗 Diet Recommendations

Eat a balanced diet.
Avoid alcohol.
Stay hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

This medicine is usually given for short-term relief. Do not stop without consulting your doctor if you are on a prescribed regimen. If you experience any serious side effects, seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine at high doses can lead to liver damage and kidney problems. Regular monitoring of liver and kidney function is recommended for patients on prolonged therapy. It is important not to exceed the recommended dose.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral paracetamol

Can be used when oral administration is feasible.

Evidence: Well-established
Non-steroidal anti-inflammatory drugs (NSAIDs)

May be used for pain and fever, but have different side effect profiles.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. It can be used to manage fever or pain after vaccination if needed.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of the prescription. Store it at room temperature and protect it from extreme temperatures. If traveling across time zones, consult your doctor for dose adjustments. Check customs regulations for carrying injectable medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with severe headache and fever after surgery
He was unable to take oral medications due to nausea. He received this medicine as an intramuscular injection. Within 15 minutes, his pain and fever subsided significantly. He experienced mild injection site pain, which resolved quickly.
💡 Lesson: This medicine provides rapid relief when oral administration is not possible.
👤 A 60-year-old woman with osteoarthritis and liver cirrhosis
She was prescribed this medicine for pain but her doctor adjusted the dose due to her liver condition. She was monitored closely and did not experience any adverse effects.
💡 Lesson: Dose adjustment is crucial in patients with liver disease to prevent toxicity.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 5-10 minutes after intravenous administration and within 10-30 minutes after intramuscular administration.

Q: How long does the effect last?

A: The analgesic and antipyretic effects last for approximately 4-6 hours.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

Q: Can I take it with other painkillers?

A: Consult your doctor before combining with other painkillers to avoid overdose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for biocetamol 150mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Paracetamol injections are stronger than tablets.
    Fact: The injection provides faster onset but the same analgesic effect as oral paracetamol when equivalent doses are used.
  • Myth: Paracetamol is completely safe at any dose.
    Fact: Exceeding the recommended dose can cause severe liver damage.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol injection 150mg

Brand Alternatives

  • Aeknil injection

📊 Comparison with Similar Medicines

[{"medicine":"Paracetamol injection","onset":"5-10 minutes","duration":"4-6 hours","route":"Parenteral"},{"medicine":"Paracetamol oral","onset":"30-60 minutes","duration":"4-6 hours","route":"Oral"}]

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