bimaton t eye drop - Bimatoprost (0.03% w/v) + Timolol (0.5% w/v) medicine

bimaton t eye drop - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Flagship Biotech International ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 2, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 02, 2026

What is bimaton t eye drop used for?

Bimat LS TM Eye Drop (Bimatoprost + Timolol) is used to treat OPHTHAL. It contains Bimatoprost (0.03% w/v) + Timolol (0.5% w/v), which Bimatoprost increases aqueous humor outflow via the uveoscleral pathway; Timolol. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Bimatoprost + Timolol
  • Manufacturer: Flagship Biotech International
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š bimaton t eye drop Uses & Benefits

Reduction of elevated intraocular pressure in open-angle glaucoma or ocular hypertension.

Off-label uses: May be used for ocular hypertension in pediatric patients (limited data).

๐Ÿ“‹ Drug Information

Generic Name(s)Bimatoprost + Timolol
Brand NameBimat LS TM Eye Drop
ManufacturerFlagship Biotech International
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassProstaglandin analog + Beta-blocker
Route of AdministrationOphthalmic (topical)
StorageStore at 2-8ยฐC (refrigerate) before opening; after opening, store at room temperature (15-25ยฐC) for up to 4 weeks.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSystemic absorption occurs through the conjunctiva, cornea, and nasal mucosa. Peak plasma concentrations are low due to small dose and local administration.
DistributionDistributes to ocular tissues; systemic distribution is minimal due to low plasma levels.
Protein BindingBimatoprost: ~88% bound to plasma proteins; Timolol: ~60% bound.
MetabolismBimatoprost undergoes hydrolysis and oxidation; Timolol is metabolized by CYP2D6.
Half-LifeBimatoprost: ~45 minutes; Timolol: ~4 hours.
ExcretionBimatoprost: primarily renal; Timolol: renal (20% unchanged) and fecal.
BioavailabilityLow systemic bioavailability due to local administration and first-pass metabolism.
Onset of ActionReduction in intraocular pressure (IOP) begins within 1-2 hours.
Peak Plasma TimeBimatoprost: ~10 minutes; Timolol: ~1-2 hours after topical application.
Duration of ActionIOP reduction lasts up to 24 hours.

How It Works

Bimatoprost increases aqueous humor outflow via the uveoscleral pathway; Timolol reduces aqueous humor production by blocking beta-adrenergic receptors in the ciliary epithelium.

Mechanism Steps

1Bimatoprost binds to FP receptors in the ciliary muscle and trabecular meshwork.
2Activation of FP receptors increases matrix metalloproteinase activity.
3Remodeling of extracellular matrix in the ciliary muscle increases uveoscleral outflow.

๐Ÿ’ก How to Take bimaton t eye drop

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bimaton t eye drop

โœ… Common Side Effects

  • Ocular hyperemia
  • Eye pruritus
  • Burning/stinging
  • Conjunctival folliculosis
  • Blurred vision
  • Eyelash growth
  • Periorbital skin darkening

๐Ÿšจ Serious Side Effects

  • Bronchospasm
  • Bradycardia
  • Heart block
  • Hypotension
  • Syncope
  • Macular edema
  • Uveitis

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Depression
  • Confusion
  • Hair loss
  • Iris darkening

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Systemic beta-blockers Major Additive bradycardia and hypotension
Calcium channel blockers Major Increased risk of heart block and hypotension
Digitalis glycosides Major Additive bradycardia
Reserpine Major Additive hypotension and bradycardia
Oral hypoglycemics Moderate Masking of hypoglycemia symptoms
Insulin Moderate Masking of hypoglycemia symptoms
MAO inhibitors Moderate Potential hypertensive crisis
Antihypertensives Moderate Additive hypotensive effect
Topical ophthalmic drugs Minor Possible additive ocular effects
Corticosteroids Minor May increase IOP

๐Ÿšจ Major Interactions

  • Beta-blockers (systemic)
  • Calcium channel blockers
  • Digitalis glycosides
  • Catecholamine-depleting drugs (e.g., reserpine)

โšก Moderate Interactions

  • Oral hypoglycemics
  • Insulin
  • MAO inhibitors
  • Antihypertensives

โ„น๏ธ Minor Interactions

  • Topical ophthalmic drugs
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Alcohol may increase systemic absorption and side effects; avoid excessive consumption.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Bronchial asthma, severe COPD, sinus bradycardia, second- or third-degree AV block, overt cardiac failure, cardiogenic shock, hypersensitivity to any component.

๐Ÿ“Š Monitoring Parameters

Intraocular pressure, heart rate, blood pressure, signs of ocular irritation, pulmonary function in asthmatics.

๐Ÿคฑ Lactation Safety

Not recommended; Timolol is excreted in breast milk; Bimatoprost may be excreted.

๐Ÿ’Š Overdose Management

If accidental ingestion, treat symptomatically; bradycardia may be treated with atropine; hypotension with vasopressors.

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jul 02, 2026

๐Ÿ”— View Profile

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