Bimato-T Eye Drop - Uses, Price, Side Effects, Dosage
What is bimato-t eye drop used for?
Bimato-T Eye Drop is a combination of Bimatoprost (0.03% w/v) and Timolol (0.5% w/v) used to lower elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Bimatoprost increases outflow of aqueous humor, while Timolol reduces its production, together effectively reducing eye pressure.
- Generic Name: Bimatoprost + Timolol
- Manufacturer: Care Formulation Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bimato-t eye drop Uses & Benefits
Reduction of elevated intraocular pressure in open-angle glaucoma or ocular hypertension.
Off-label uses: May be used for ocular hypertension in pediatric patients (limited data).
๐ Drug Information
| Generic Name(s) | Bimatoprost + Timolol |
| Brand Name | Bimat LS TM Eye Drop |
| Manufacturer | Care Formulation Labs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Prostaglandin analog + Beta-blocker |
| Route of Administration | Ophthalmic (topical) |
| Storage | Store at 2-8ยฐC (refrigerate) before opening; after opening, store at room temperature (15-25ยฐC) for up to 4 weeks. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Bimatoprost increases aqueous humor outflow via the uveoscleral pathway; Timolol reduces aqueous humor production by blocking beta-adrenergic receptors in the ciliary epithelium.
Mechanism Steps
๐ก How to Take bimato-t eye drop
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of bimato-t eye drop
โ Common Side Effects
- Ocular hyperemia
- Eye pruritus
- Burning/stinging
- Conjunctival folliculosis
- Blurred vision
- Eyelash growth
- Periorbital skin darkening
๐จ Serious Side Effects
- Bronchospasm
- Bradycardia
- Heart block
- Hypotension
- Syncope
- Macular edema
- Uveitis
โ ๏ธ Rare Side Effects
- Anaphylaxis
- Depression
- Confusion
- Hair loss
- Iris darkening
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Beta-blockers (systemic) | Major | Additive bradycardia and hypotension |
| Calcium channel blockers | Moderate | Increased risk of heart block |
| Digoxin | Moderate | Enhanced bradycardic effect |
๐จ Major Interactions
- Beta-blockers (systemic)
- Calcium channel blockers
- Digitalis glycosides
- Catecholamine-depleting drugs (e.g., reserpine)
โก Moderate Interactions
- Oral hypoglycemics
- Insulin
- MAO inhibitors
- Antihypertensives
โน๏ธ Minor Interactions
- Topical ophthalmic drugs
- Corticosteroids
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Alcohol may increase systemic absorption and side effects; avoid excessive consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Bronchial asthma, severe COPD, sinus bradycardia, second- or third-degree AV block, overt cardiac failure, cardiogenic shock, hypersensitivity to any component.
๐ Monitoring Parameters
Intraocular pressure, heart rate, blood pressure, signs of ocular irritation, pulmonary function in asthmatics.
๐คฑ Lactation Safety
Not recommended; Timolol is excreted in breast milk; Bimatoprost may be excreted.
๐ Overdose Management
If accidental ingestion, treat symptomatically; bradycardia may be treated with atropine; hypotension with vasopressors.
โฐ Missed Dose
Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule.