bigflur g eye drop - Flurbiprofen (0.03% w/v) + Gatifloxacin (0.3% w/v) medicine

bigflur g eye drop

4.4 (14 reviews)
๐Ÿญ Doctor Wonder Private Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is bigflur g eye drop used for?

Bigflur G Eye Drop (Flurbiprofen + Gatifloxacin) is used to treat OPHTHAL. It contains Flurbiprofen (0.03% w/v) + Gatifloxacin (0.3% w/v), which Flurbiprofen inhibits cyclooxygenase (COX), reducing prostaglandin synthesis; Ga. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Flurbiprofen + Gatifloxacin
  • Manufacturer: Doctor Wonder Private Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š bigflur g eye drop Uses & Benefits

Postoperative ocular inflammation and prevention of infection, bacterial conjunctivitis, keratitis

Off-label uses: Corneal abrasion, dry eye (anti-inflammatory component)

๐Ÿ“‹ Drug Information

Generic Name(s)Flurbiprofen + Gatifloxacin
Brand NameBigflur G Eye Drop
ManufacturerDoctor Wonder Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassNSAID + Fluoroquinolone Antibiotic
Route of AdministrationOphthalmic (topical)
StorageStore at 15-30ยฐC, protect from light, keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption following ocular administration
DistributionPrimarily local ocular distribution
Protein BindingFlurbiprofen: >99%; Gatifloxacin: ~20%
MetabolismFlurbiprofen: Hepatic (CYP2C9); Gatifloxacin: Limited hepatic metabolism
Half-LifeFlurbiprofen: 5-7 hours; Gatifloxacin: 7-14 hours
ExcretionFlurbiprofen: Renal; Gatifloxacin: Renal (primarily unchanged)
BioavailabilityLow systemic bioavailability due to ocular route
Onset of ActionRapid (within minutes for anti-inflammatory effect)
Peak Plasma TimeNot applicable for ocular use
Duration of ActionFlurbiprofen: 4-6 hours; Gatifloxacin: 12 hours

How It Works

Flurbiprofen inhibits cyclooxygenase (COX), reducing prostaglandin synthesis; Gatifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication

Mechanism Steps

1Flurbiprofen inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis
2Decreased prostaglandins lead to reduced inflammation and pain
3Gatifloxacin enters bacterial cells and binds to DNA gyrase and topoisomerase IV

๐Ÿ’ก How to Take bigflur g eye drop

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bigflur g eye drop

โœ… Common Side Effects

  • Eye irritation
  • Stinging
  • Blurred vision
  • Tearing

๐Ÿšจ Serious Side Effects

  • Corneal ulceration
  • Perforation
  • Increased intraocular pressure
  • Hypersensitivity reactions

โš ๏ธ Rare Side Effects

  • Tendon rupture (systemic gatifloxacin)
  • QT prolongation
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Cyclosporine Major Increased nephrotoxicity
Aspirin Moderate Increased GI side effects
Corticosteroids Moderate Increased risk of GI ulceration
Antacids Minor Reduced absorption of gatifloxacin

๐Ÿšจ Major Interactions

  • Warfarin
  • Anticoagulants
  • Methotrexate
  • Lithium
  • Cyclosporine

โšก Moderate Interactions

  • Aspirin
  • Other NSAIDs
  • Corticosteroids
  • Antidiabetic agents

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol as it may increase risk of gastrointestinal bleeding

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, history of asthma or urticaria with NSAIDs, viral keratitis, fungal infections

๐Ÿ“Š Monitoring Parameters

Intraocular pressure, corneal integrity, signs of infection or hypersensitivity

๐Ÿคฑ Lactation Safety

Use with caution; limited data

๐Ÿ’Š Overdose Management

Not expected with ocular use; if ingested, symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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