bigdap 60mg tablet - Dapoxetine (60mg) medicine

Bigdap 60mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Ryon Pharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is bigdap 60mg tablet used for?

Bigdap 60mg Tablet contains Dapoxetine, a selective serotonin reuptake inhibitor used to treat premature ejaculation. It works by increasing serotonin levels in the brain, delaying ejaculation. Take it 1-3 hours before sexual activity as directed.

  • Generic Name: Dapoxetine
  • Manufacturer: Ryon Pharma
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š bigdap 60mg tablet Uses & Benefits

Treatment of premature ejaculation in men aged 18-64 years.

Off-label uses: None established.

๐Ÿ“‹ Drug Information

Generic Name(s)Dapoxetine
Brand NameAppynite
ManufacturerRyon Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassSelective Seretonin Reuptake inhibitors (SSRIs)
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached in 1-2 hours.
DistributionDistributed widely; volume of distribution approximately 1.5 L/kg.
Protein BindingApproximately 99% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP2D6, CYP3A4, and flavin-containing monooxygenase (FMO1) to multiple metabolites.
Half-LifeApproximately 1.5 hours (range 0.5-2.5 hours).
ExcretionPrimarily excreted in urine as metabolites; less than 3% excreted unchanged.
BioavailabilityApproximately 42% (due to first-pass metabolism).
Onset of ActionWithin 1 hour.
Peak Plasma Time1-2 hours.
Duration of ActionUp to 4-6 hours.

How It Works

Selective serotonin reuptake inhibitor (SSRI) that increases serotonin activity in the synaptic cleft, delaying ejaculation.

Mechanism Steps

1Dapoxetine binds to the serotonin transporter (SERT) on presynaptic neurons.
2Inhibition of serotonin reuptake increases serotonin concentration in the synaptic cleft.
3Enhanced serotonergic neurotransmission activates postsynaptic serotonin receptors.

๐Ÿ’ก How to Take bigdap 60mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โŒ โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of bigdap 60mg tablet

โœ… Common Side Effects

  • Nausea
  • Dizziness
  • Headache
  • Diarrhea
  • Insomnia
  • Fatigue

๐Ÿšจ Serious Side Effects

  • Syncope
  • Orthostatic hypotension
  • Serotonin syndrome
  • Suicidal ideation
  • Seizures

โš ๏ธ Rare Side Effects

  • QT prolongation
  • Allergic reactions
  • Liver injury
  • Mania

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of serotonin syndrome
SSRIs Major Additive serotonergic effects
Alcohol Moderate Increased dizziness and sedation

๐Ÿšจ Major Interactions

  • MAOIs
  • Thioridazine
  • Linezolid
  • Methylene blue
  • Serotonergic drugs (e.g., SSRIs, SNRIs, triptans)
  • CYP2D6 inhibitors (e.g., paroxetine, fluoxetine, quinidine)

โšก Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • Alcohol
  • CNS depressants

โ„น๏ธ Minor Interactions

  • CYP2D6 substrates
  • CYP3A4 substrates

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

Increased risk of orthostatic hypotension, dizziness, and syncope; avoid alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to dapoxetine, concurrent MAOI use, severe hepatic impairment, moderate to severe renal impairment, history of syncope, mania, or bipolar disorder.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, signs of serotonin syndrome, syncope, orthostatic hypotension.

๐Ÿคฑ Lactation Safety

Not indicated for use in women; excretion in breast milk unknown.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care, monitor for serotonin syndrome, ECG monitoring.

โฐ Missed Dose

Take as needed 1-3 hours before sexual activity; do not take more than once daily.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bigdap 60mg tablet

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Alternative brands with exact same active ingredient (Dapoxetine (60mg)):

Medical Note: Always consult your doctor before switching medications.

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