alkacitral liquid - Disodium Hydrogen Citrate (1.25gm/5ml) medicine

alkacitral liquid

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🏭 Alembic Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
🤰 Pregnancy Category C 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is alkacitral liquid used for?

This medicine contains Disodium Hydrogen Citrate (1.25gm/5ml) and is used to treat UROLOGY. Alkalizes urine by increasing bicarbonate excretion and reducing hydrogen ion concentration.. Always consult your doctor before use.

  • Generic Name: Disodium Hydrogen Citrate
  • Manufacturer: Alembic Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 alkacitral liquid Uses & Benefits

Treatment of metabolic acidosis, alkalinization of urine to prevent uric acid stones, and as a urinary alkalizer.

Off-label uses: May be used in some cases of cystinuria or to enhance excretion of weak acids in poisoning.

📋 Drug Information

Generic Name(s)Disodium Hydrogen Citrate
Brand NameAlkasol Oral Solution
ManufacturerAlembic Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassUROLOGY
Action ClassUricosuric agent-gout
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract.
DistributionDistributes throughout extracellular fluid.
Protein BindingNot significantly protein bound.
MetabolismMetabolized in the liver via the citric acid cycle.
Half-LifeApproximately 1-2 hours.
ExcretionExcreted primarily in urine as bicarbonate and citrate.
BioavailabilityHigh, due to rapid absorption.
Onset of ActionWithin 15-30 minutes.
Peak Plasma Time1-2 hours.
Duration of Action2-4 hours.

How It Works

Alkalizes urine by increasing bicarbonate excretion and reducing hydrogen ion concentration.

Mechanism Steps

1Ingested disodium hydrogen citrate dissociates into sodium and citrate ions.
2Citrate is metabolized in the liver to bicarbonate.
3Bicarbonate is excreted in urine, increasing urinary pH.
4Increased pH reduces hydrogen ion concentration and promotes dissolution of uric acid stones.

💡 How to Take alkacitral liquid

Follow your doctor's prescription exactly.

⚠️ Side Effects of alkacitral liquid

✅ Common Side Effects

Nausea
Diarrhea
Abdominal discomfort

🚨 Serious Side Effects

Metabolic alkalosis
Hypernatremia
Hypocalcemia

⚠️ Rare Side Effects

Tetany
Seizures
Cardiac arrhythmias

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Lithium Major Increased lithium excretion and reduced efficacy.
Methotrexate Major Increased methotrexate excretion and reduced efficacy.
Salicylates Major Increased salicylate excretion and reduced efficacy.
Antacids Moderate Enhanced alkalinizing effect.
Calcium supplements Moderate Risk of calcium phosphate stone formation.
Corticosteroids Moderate Increased sodium retention.
Vitamin C Minor May reduce alkalinizing effect.
Cranberry juice Minor May reduce alkalinizing effect.

🚨 Major Interactions

  • Lithium
  • Methotrexate
  • Salicylates

⚡ Moderate Interactions

  • Antacids
  • Calcium supplements
  • Corticosteroids

🍷 Alcohol Interaction

No significant interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Severe renal impairment, metabolic alkalosis, hypocalcemia, and patients on sodium-restricted diets.

🤱 Lactation Safety

Generally considered safe; excreted in breast milk in small amounts.

💊 Overdose Management

Induce vomiting or gastric lavage; monitor electrolytes and acid-base balance; administer calcium gluconate if hypocalcemia occurs.

⏰ Missed Dose

Take as soon as remembered unless it is almost time for the next dose; do not double dose.

🔄 Substitutes for alkacitral liquid

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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