bextrin capsule - Aceclofenac (100mg) + Beta-Cyclodextrin (100mg) medicine

bextrin capsule

4.5 (19 reviews)
๐Ÿญ Pharmanova India Drugs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is bextrin capsule used for?

Bextrin Capsule (Aceclofenac + Beta-Cyclodextrin) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Beta-Cyclodextrin (100mg), which Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthe. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Beta-Cyclodextrin
  • Manufacturer: Pharmanova India Drugs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š bextrin capsule Uses & Benefits

Pain management (osteoarthritis, rheumatoid arthritis, dental pain, dysmenorrhea).

Off-label uses: Acute gout, postoperative pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Aceclofenac + Beta-Cyclodextrin
Brand NameBextrin Capsule
ManufacturerPharmanova India Drugs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAIDs (Nonsteroidal Anti-inflammatory Drugs)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; beta-cyclodextrin enhances solubility and absorption.
DistributionWidely distributed; crosses placenta and enters breast milk.
Protein Binding>99% (aceclofenac)
MetabolismHepatic; primarily via CYP2C9 to active metabolite diclofenac.
Half-Life4-5 hours (aceclofenac)
ExcretionRenal (primarily as metabolites); some biliary excretion.
Bioavailability~100% (enhanced by beta-cyclodextrin)
Onset of Action30-60 minutes
Peak Plasma Time1-3 hours
Duration of Action12-24 hours

How It Works

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.

Mechanism Steps

1Aceclofenac is absorbed and converted to diclofenac.
2Diclofenac inhibits COX-1 and COX-2 enzymes.
3Reduction in prostaglandin synthesis from arachidonic acid.

๐Ÿ’ก How to Take bextrin capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bextrin capsule

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Diarrhea
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Aplastic anemia
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased GI ulceration risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
ACE inhibitors Major Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic efficacy
Corticosteroids Moderate Increased GI ulcer risk
Anticoagulants Moderate Increased bleeding risk
SSRIs Moderate Increased bleeding risk
Antacids Minor Reduced absorption
Cholestyramine Minor Reduced absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Lithium
  • Methotrexate
  • ACE inhibitors

โšก Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Anticoagulants
  • SSRIs

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but not extent.

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active GI bleeding, severe renal/hepatic impairment, third trimester pregnancy, history of asthma with NSAIDs.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood pressure, signs of GI bleeding.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid or use with caution.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

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