betrol forte 5mg/500mg tablet
What is betrol forte 5mg/500mg tablet used for?
Aviglen Forte Tablet (Glibenclamide + Metformin) is used to treat ANTI DIABETIC. It contains Glibenclamide (5mg) + Metformin (500mg), which Glibenclamide: Stimulates insulin release from pancreatic beta cells; Metformin:. Always consult your doctor before use. Take as prescribed.
- Generic Name: Glibenclamide + Metformin
- Manufacturer: Jpee Drugs
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ betrol forte 5mg/500mg tablet Uses & Benefits
Type 2 diabetes mellitus when diet and exercise alone are insufficient.
Off-label uses: Polycystic ovary syndrome (metformin component).
๐ Drug Information
| Generic Name(s) | Glibenclamide + Metformin |
| Brand Name | Aviglen Forte Tablet |
| Manufacturer | Jpee Drugs |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylurea + Biguanide |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Glibenclamide: Stimulates insulin release from pancreatic beta cells; Metformin: Decreases hepatic glucose production, increases insulin sensitivity.
Mechanism Steps
๐ก How to Take betrol forte 5mg/500mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of betrol forte 5mg/500mg tablet
โ Common Side Effects
- Hypoglycemia
- Gastrointestinal upset
- Nausea
- Diarrhea
- Metallic taste
๐จ Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hepatic injury
- Pancreatitis
โ ๏ธ Rare Side Effects
- Aplastic anemia
- Agranulocytosis
- Cholestatic jaundice
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Miconazole | Major | Enhanced hypoglycemic effect |
| Bosentan | Major | Decreased efficacy of glibenclamide |
| ACE inhibitors | Moderate | Enhanced hypoglycemic effect |
| Beta-blockers | Moderate | Mask hypoglycemia symptoms |
| Corticosteroids | Moderate | Hyperglycemia |
| Diuretics | Moderate | Hyperglycemia |
| NSAIDs | Moderate | Enhanced hypoglycemic effect |
| Cimetidine | Minor | Increased metformin levels |
| Ranitidine | Minor | Increased metformin levels |
๐จ Major Interactions
- Insulin
- Other sulfonylureas
- Miconazole
- Bosentan
โก Moderate Interactions
- ACE inhibitors
- Beta-blockers
- Corticosteroids
- Diuretics
- NSAIDs
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
๐ฝ๏ธ Food Interactions
Alcohol may increase risk of lactic acidosis; avoid excessive alcohol.
๐ท Alcohol Interaction
Increased risk of lactic acidosis and hypoglycemia.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Renal impairment (eGFR <30 mL/min), hepatic impairment, metabolic acidosis, hypersensitivity, type 1 diabetes, diabetic ketoacidosis.
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function, liver function, lactic acidosis symptoms.
๐คฑ Lactation Safety
Not recommended; glibenclamide excreted in milk, metformin may be excreted.
๐ Overdose Management
Monitor blood glucose; treat hypoglycemia with oral glucose or IV dextrose; lactic acidosis requires hemodialysis.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.