Labetalol 100mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow heart rate (below 50 beats per minute)
- Difficulty breathing or wheezing
- Swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes (jaundice)
- Dark urine or severe abdominal pain
- Chest pain or irregular heartbeat
- Sudden severe headache or vision changes
If experiencing severe symptoms, call emergency services immediately.
What is beta-l tablet used for?
Labetalol is a combined alpha- and beta-blocker used to treat high blood pressure. It works by relaxing blood vessels and slowing the heart rate. The usual adult dose is 100 mg twice daily, adjusted as needed. It is also safe in pregnancy under medical supervision.
- Generic Name: Labetalol (100mg)
- Manufacturer: Wohltat Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 beta-l tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेबेटालोल नामक तत्व से बनी है, जो उच्च रक्तचाप (हाई ब्लड प्रेशर) को नियंत्रित करने में मदद करती है। यह अल्फा और बीटा दोनों रिसेप्टर्स को ब्लॉक करती है, जिससे रक्त वाहिकाएं फैलती हैं और हृदय की गति धीमी होती है। इसका उपयोग गर्भावस्था के दौरान भी किया जा सकता है, लेकिन डॉक्टर की सलाह से ही। यह दवा दिल के दौरे और स्ट्रोक के खतरे को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, जी मिचलाना और खोपड़ी में झुनझुनी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी धड़कन धीमी हो सकती है, हाथ-पैर ठंडे लग सकते हैं, या नींद न आने की समस्या हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में तकलीफ, चेहरे या गले में सूजन, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें, क्योंकि इससे रक्तचाप खतरनाक रूप से बढ़ सकता है। दवा लेते समय चक्कर आ सकते हैं, इसलिए उठते समय धीरे-धीरे उठें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी चलाने या मशीन चलाने से बचें। शराब न पिएं। अपने डॉक्टर को बताएं कि आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।
💊 beta-l tablet Uses & Benefits
[{"condition":"Hypertension","description":"Labetalol is used to lower high blood pressure by reducing peripheral vascular resistance and heart rate.","evidence":"Well-established"},{"condition":"Hypertensive emergencies","description":"Intravenous labetalol is used for rapid blood pressure control in hypertensive crises, but this oral tablet is for chronic management.","evidence":"Well-established"},{"condition":"Hypertension in pregnancy","description":"Labetalol is commonly used to manage chronic and gestational hypertension during pregnancy when benefits outweigh risks.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Labetalol may be used to reduce angina attacks by decreasing heart rate and blood pressure, but it is not a first-line treatment.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Anxiety with autonomic symptoms","description":"Occasionally used off-label to manage physical symptoms of anxiety, but not a standard treatment.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Hypertensive emergencies, Angina pectoris, Hypertension in pregnancy
📋 Drug Information
| Generic Name(s) | Labetalol (100mg) |
| Brand Name | beta-l tablet |
| Manufacturer | Wohltat Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Alpha & beta blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture, heat, and direct sunlight. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization includes labetalol in its list of essential medicines for the treatment of hypertension, including in pregnancy. |
| ICMR Guideline | The Indian Council of Medical Research recommends labetalol as a safe and effective option for managing hypertension in pregnancy. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Labetalol is a unique antihypertensive agent that competitively blocks both alpha-1 adrenergic receptors and beta-adrenergic receptors. Its beta-blocking effect is non-selective, affecting both beta-1 and beta-2 receptors, while its alpha-blocking effect is selective for alpha-1 receptors. By blocking beta-1 receptors in the heart, it reduces heart rate and contractility, thereby decreasing cardiac output. Blocking alpha-1 receptors in blood vessels causes vasodilation, reducing peripheral vascular resistance. The combined effect leads to a reduction in blood pressure without a significant reflex tachycardia. Additionally, labetalol has some intrinsic sympathomimetic activity and membrane-stabilizing effects, but these are not clinically significant at usual doses.
Mechanism Steps
💡 How to Take beta-l tablet
Strength: Labetalol 100 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for adults is 100 mg taken twice daily (morning and evening), with or without food. Your doctor may increase the dose gradually based on your blood pressure response, typically at intervals of 2 to 3 days. The usual maintenance dose ranges from 200 mg to 400 mg twice daily. For severe hypertension, doses up to 2400 mg per day may be used in divided doses. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of labetalol, especially dizziness and low blood pressure. Start with a lower dose and titrate slowly. Monitor kidney and liver function regularly. |
| Renal Impairment | No specific dose adjustment is required for mild to moderate renal impairment. In severe renal impairment, use with caution and monitor closely. |
| Hepatic Impairment | In patients with liver disease, the half-life of labetalol is prolonged. Start with a lower dose and titrate slowly. Monitor liver function tests. |
| Maximum Daily Dose | The maximum recommended daily dose is 2400 mg, divided into two or three doses. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of beta-l tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| MAOIs | Major | |
| NSAIDs | Moderate | |
| Albuterol | Moderate | |
| Insulin | Moderate | |
| Antacids | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Calcium channel blockers (e.g., verapamil, diltiazem)
- Clonidine
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Beta-2 agonists (e.g., albuterol)
- Insulin and oral hypoglycemics
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of labetalol, leading to dizziness, fainting, and orthostatic hypotension. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Asthma or severe chronic obstructive pulmonary disease (COPD)","Severe bradycardia","Second- or third-degree heart block","Cardiogenic shock","Severe liver disease","Hypersensitivity to labetalol"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly; taper gradually to avoid rebound hypertension.","Use with caution in patients with diabetes, as it may mask hypoglycemia symptoms.","May worsen symptoms of Raynaud's phenomenon or peripheral vascular disease.","Use with caution in patients with a history of severe allergic reactions.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have kidney or liver disease.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Labetalol is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of labetalol can cause severe low blood pressure, slow heart rate, heart failure, and bronchospasm. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, atropine for bradycardia, and vasopressors for hypotension. Hemodialysis is not effective for removing labetalol.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Safety is paramount when taking this medicine. Always take it exactly as prescribed by your doctor. Do not change the dose or stop taking it suddenly, as this can cause a dangerous rise in blood pressure or heart problems. This medicine can cause dizziness, especially when you stand up quickly, so rise slowly from a sitting or lying position. Avoid driving or operating heavy machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may pass into breast milk, so discuss with your doctor if you are nursing. Keep all your doctor appointments and get your blood pressure, heart rate, and liver function checked regularly. Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Tell your doctor about all other medicines, supplements, and herbal products you are taking, as many can interact with this medicine. Store this medicine at room temperature, away from moisture and heat. Keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering and heart rate-slowing effects of labetalol. Start with a lower dose and titrate slowly. Monitor for dizziness, falls, and orthostatic hypotension. Regular kidney and liver function tests are recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor. Labetalol is considered safe during pregnancy, but your dose may need adjustment. Do not stop or change the medicine without medical advice.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking labetalol before any surgery. It may interact with anesthetic agents and affect heart rate and blood pressure. Your doctor may adjust the dose or temporarily switch to another medicine.
🦷 Dental Procedures
Tell your dentist that you are taking labetalol before any dental procedure. It may interact with local anesthetics containing epinephrine, potentially causing blood pressure changes. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe and beneficial while taking labetalol. However, because labetalol can cause dizziness and slow heart rate, avoid strenuous activities or heavy lifting until you know how the medicine affects you. Stay hydrated and rise slowly after exercise to prevent dizziness.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Labetalol may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work and daily activities with dose adjustment. Inform your employer if your job involves operating machinery or driving.
🛑 When to Stop This Medicine
Do not stop taking labetalol without consulting your doctor. Abrupt discontinuation can cause rebound hypertension, chest pain, or heart attack. Your doctor will gradually reduce the dose if needed. If you experience severe side effects, contact your doctor immediately for advice.
📅 Long-Term Use Effects
Long-term use of labetalol is generally safe when monitored by a doctor. Regular check-ups should include blood pressure, heart rate, liver function, and kidney function tests. Prolonged use may lead to tolerance, requiring dose adjustments. Do not stop the medicine without medical advice. Long-term benefits include reduced risk of heart attack, stroke, and kidney damage from uncontrolled hypertension.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, calcium channel blockers, or diuretics may be alternatives if labetalol is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between labetalol and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry your labetalol tablets in their original packaging with a copy of your prescription. Keep them in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust your dosing schedule gradually in consultation with your doctor. Carry enough supply for the entire trip plus extra in case of delays. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Labetalol starts lowering blood pressure within 20 minutes to 2 hours after oral intake, but full effect may take a few days to weeks.
A: No, do not stop suddenly. High blood pressure often has no symptoms, and stopping abruptly can cause dangerous rebound hypertension. Consult your doctor first.
A: Labetalol is considered safe during pregnancy when prescribed and monitored by a doctor. It is commonly used to treat hypertension in pregnant women.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for beta-l tablet
View AllAlternative brands with exact same active ingredient:
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davaindia labetalol 100mg tabletDavaindia Generic Pharmacy ₹45.00 62.8% CHEAPER
-
stayhappi labetalol 100mg tabletSarvagunaushdhi Pvt Ltd ₹56.25 53.5% CHEAPER
-
labebet 100mg injectionSun Pharmaceutical Industries Ltd ₹93.61 22.6% CHEAPER
-
evabet 100mg tabletCelon Laboratories Ltd ₹93.75 22.5% CHEAPER
-
cebalol 100mg tabletHealth Biotech Limited ₹100.00 17.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Labetalol is only for pregnant women.
Fact: Labetalol is used for hypertension in both men and women, though it is commonly prescribed in pregnancy. - Myth: You can stop labetalol once your blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping suddenly can cause dangerous rebound hypertension. Always consult your doctor before stopping. - Myth: Labetalol causes weight gain.
Fact: Labetalol is not typically associated with weight gain; some beta-blockers may cause weight gain, but labetalol is less likely to do so.
🔄 Alternative Options
Generic Alternatives
- Labetalol hydrochloride 100 mg tablet
Brand Alternatives
- Beta-L 100 mg tablet
- Labetalol 100 mg tablet (various manufacturers)