bestofyline 100mg syrup - Doxofylline (100mg) medicine

Bestofyline 100mg Syrup - Uses, Price, Side Effects

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๐Ÿญ BestoChem Formulations India Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 4, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 04, 2026

What is bestofyline 100mg syrup used for?

Bestofyline 100mg Syrup contains Doxofylline, a bronchodilator used to treat asthma and chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles in the airways, making breathing easier. It is typically taken twice daily. Common side effects include headache, nausea, and insomnia. Always consult your doctor before use.

  • Generic Name: Doxofylline
  • Manufacturer: BestoChem Formulations India Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š bestofyline 100mg syrup Uses & Benefits

Bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis

Off-label uses: None established

๐Ÿ“‹ Drug Information

Generic Name(s)Doxofylline
Brand NameAmril Plus 400mg Tablet
ManufacturerBestoChem Formulations India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassTheophylline & its derivatives
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionWidely distributed in body tissues
Protein BindingApproximately 50%
MetabolismHepatic metabolism via CYP450 enzymes
Half-Life6-8 hours
ExcretionRenal excretion (primarily as metabolites)
Bioavailability60-70%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action12 hours

How It Works

Inhibits phosphodiesterase (PDE) enzymes, leading to increased intracellular cAMP and cGMP, resulting in bronchodilation and anti-inflammatory effects

Mechanism Steps

1Doxofylline enters bronchial smooth muscle cells
2Inhibits phosphodiesterase (PDE) enzymes, especially PDE4
3Prevents breakdown of intracellular cAMP and cGMP

๐Ÿ’ก How to Take bestofyline 100mg syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of bestofyline 100mg syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Headache
  • Insomnia
  • Dizziness
  • Tachycardia

๐Ÿšจ Serious Side Effects

  • Seizures
  • Arrhythmias
  • Severe hypotension
  • Hypersensitivity reactions

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Nephrotoxicity
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Theophylline Major Increased risk of toxicity
Cimetidine Moderate Increased Doxofylline levels
Ciprofloxacin Moderate Increased Doxofylline levels

๐Ÿšจ Major Interactions

  • Theophylline
  • Cimetidine
  • Ciprofloxacin
  • Erythromycin
  • Fluvoxamine

โšก Moderate Interactions

  • Lithium
  • Beta-blockers
  • Phenytoin
  • Carbamazepine

โ„น๏ธ Minor Interactions

  • Caffeine
  • Alcohol
  • Smoking

๐Ÿฝ๏ธ Food Interactions

High-fat meals may delay absorption; avoid excessive caffeine intake

๐Ÿท Alcohol Interaction

May increase risk of side effects like dizziness and headache

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Moderate
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to doxofylline or any excipients, acute myocardial infarction, hypotension, seizure disorders

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, serum doxofylline levels (if toxicity suspected), ECG in elderly or cardiac patients

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, symptomatic treatment; monitor cardiac and CNS effects

โฐ Missed Dose

Take as soon as remembered unless almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 04, 2026

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๐Ÿ”„ Substitutes for bestofyline 100mg syrup

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Alternative brands with exact same active ingredient (Doxofylline (100mg)):

Medical Note: Always consult your doctor before switching medications.

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