beparine 1000iu injection - Uses, Price, Side Effects & Substitutes
What is beparine 1000iu injection used for?
Adhestop 25000IU Injection (Heparin) is used to treat BLOOD RELATED. It contains Heparin (1000IU), which Binds to antithrombin III, accelerating its inhibition of thrombin and factor Xa. Always consult your doctor before use. Take as prescribed.
- Generic Name: Heparin
- Manufacturer: Biological E Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ beparine 1000iu injection Uses & Benefits
Prophylaxis and treatment of venous thromboembolism (DVT, PE); treatment of acute coronary syndromes; anticoagulation during hemodialysis, cardiopulmonary bypass, and blood transfusions; initial anticoagulation in pregnancy.
Off-label uses: Anticoagulation for extracorporeal membrane oxygenation (ECMO); prevention of catheter-related thrombosis; treatment of disseminated intravascular coagulation (DIC).
๐ Drug Information
| Generic Name(s) | Heparin |
| Brand Name | Adhestop 25000IU Injection |
| Manufacturer | Biological E Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Unfractionated Heparin (UFH) |
| Route of Administration | Intravenous (IV) or subcutaneous (SC); not for intramuscular use. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from freezing; do not use if discolored or contains precipitate. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Binds to antithrombin III, accelerating its inhibition of thrombin and factor Xa.
Mechanism Steps
๐ก How to Take beparine 1000iu injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of beparine 1000iu injection
โ Common Side Effects
- Bleeding
- Pain at injection site
- Bruising
- Hematoma
- Thrombocytopenia (mild)
๐จ Serious Side Effects
- Heparin-induced thrombocytopenia (HIT)
- Major hemorrhage
- Spinal hematoma (with neuraxial anesthesia)
- Osteoporosis (long-term use)
- Hypersensitivity reactions
- Skin necrosis
โ ๏ธ Rare Side Effects
- Aldosterone suppression (hyperkalemia)
- Priapism
- Rebound hyperlipidemia
- Alopecia
- Delayed hypersensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased bleeding risk |
| NSAIDs | Major | Increased bleeding risk |
| Clopidogrel | Major | Increased bleeding risk |
| Dabigatran | Major | Increased bleeding risk |
| Rivaroxaban | Major | Increased bleeding risk |
| Apixaban | Major | Increased bleeding risk |
| Edoxaban | Major | Increased bleeding risk |
| Fondaparinux | Major | Increased bleeding risk |
| Thrombolytics | Major | Increased bleeding risk |
| Corticosteroids | Moderate | Increased bleeding risk |
| Estrogens | Moderate | Reduced anticoagulant effect |
| Progestins | Moderate | Reduced anticoagulant effect |
| Antiplatelet drugs | Moderate | Increased bleeding risk |
| SSRIs | Moderate | Increased bleeding risk |
| SNRIs | Moderate | Increased bleeding risk |
| Valproic acid | Moderate | Increased bleeding risk |
| Cephalosporins | Moderate | Increased bleeding risk |
| Penicillins | Moderate | Increased bleeding risk |
| Digoxin | Minor | Possible reduced digoxin effect |
| Quinidine | Minor | Possible reduced quinidine effect |
| Tetracyclines | Minor | Possible reduced anticoagulant effect |
| Antihistamines | Minor | Possible reduced anticoagulant effect |
| Vitamin K | Minor | Antagonizes anticoagulant effect |
๐จ Major Interactions
- Warfarin
- Aspirin
- NSAIDs
- Clopidogrel
- Dabigatran
- Rivaroxaban
- Apixaban
- Edoxaban
- Fondaparinux
- Thrombolytics
โก Moderate Interactions
- Corticosteroids
- Estrogens
- Progestins
- Antiplatelet drugs
- SSRIs
- SNRIs
- Valproic acid
- Cephalosporins
- Penicillins
โน๏ธ Minor Interactions
- Digoxin
- Quinidine
- Tetracyclines
- Antihistamines
- Vitamin K
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
May increase bleeding risk; avoid excessive alcohol consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to heparin; history of heparin-induced thrombocytopenia (HIT); active bleeding; severe thrombocytopenia; uncontrolled bleeding disorders; recent surgery of eye, brain, or spinal cord; epidural or spinal anesthesia (risk of spinal hematoma).
๐ Monitoring Parameters
aPTT (target 1.5-2.5 times control); platelet count (monitor for HIT); signs of bleeding; renal function.
๐คฑ Lactation Safety
Not excreted in breast milk; considered compatible with breastfeeding.
๐ Overdose Management
Discontinue heparin; administer protamine sulfate (1 mg per 100 units of heparin given in last 4 hours); monitor aPTT and bleeding.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose; consult physician.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for beparine 1000iu injection
View AllAlternative brands with exact same active ingredient (Heparin (1000IU)):
-
caprin flush 1000iu injectionSamarth Life Sciences Pvt Ltd โน26.25 11.6% CHEAPER
-
hethin f 1000iu injectionLa Renon Healthcare Pvt Ltd โน99.00 233.3% COSTLIER
-
nuparin 1000iu injectionTroikaa Pharmaceuticals Ltd โน108.51 265.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.