benelix br 50 mg/1.25 mg/4 mg syrup - Guaifenesin (50mg) + Terbutaline (1.25mg) medicine

benelix br 50 mg/1.25 mg/4 mg syrup

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🏭 Anglo-French Drugs & Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is benelix br 50 mg/1.25 mg/4 mg syrup used for?

This medicine contains Guaifenesin (50mg) + Terbutaline (1.25mg) and is used to treat RESPIRATORY. Guaifenesin increases respiratory tract fluid output to reduce mucus viscosity; Terbutaline stimulat. Always consult your doctor before use.

  • Generic Name: Guaifenesin + Terbutaline
  • Manufacturer: Anglo-French Drugs & Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 benelix br 50 mg/1.25 mg/4 mg syrup Uses & Benefits

Relief of productive cough associated with bronchial asthma, bronchitis, COPD

Off-label uses: Not commonly used off-label

📋 Drug Information

Generic Name(s)Guaifenesin + Terbutaline
Brand NameAsthakind Expectorant Sugar Free
ManufacturerAnglo-French Drugs & Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassExpectorant and Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (15-30°C), protect from light
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract
DistributionDistributed throughout body fluids
Protein BindingGuaifenesin: low; Terbutaline: approximately 20%
MetabolismGuaifenesin: hepatic; Terbutaline: hepatic via conjugation
Half-LifeGuaifenesin: 1 hour; Terbutaline: 3-4 hours
ExcretionRenal (both)
BioavailabilityGuaifenesin: well absorbed; Terbutaline: about 15-25%
Onset of ActionGuaifenesin: 30 minutes; Terbutaline: 15-30 minutes
Peak Plasma TimeGuaifenesin: 1 hour; Terbutaline: 2-3 hours
Duration of ActionGuaifenesin: 4-6 hours; Terbutaline: 4-6 hours

How It Works

Guaifenesin increases respiratory tract fluid output to reduce mucus viscosity; Terbutaline stimulates beta-2 adrenergic receptors causing bronchodilation

Mechanism Steps

1Guaifenesin increases respiratory tract fluid secretion, reducing mucus viscosity and facilitating expectoration.
2Terbutaline selectively stimulates beta-2 adrenergic receptors in bronchial smooth muscle, causing relaxation and bronchodilation.
3Combined action improves airway clearance and breathing.

💡 How to Take benelix br 50 mg/1.25 mg/4 mg syrup

Follow your doctor's prescription exactly.

⚠️ Side Effects of benelix br 50 mg/1.25 mg/4 mg syrup

✅ Common Side Effects

Nausea
Vomiting
Headache
Tremor
Palpitations
Dizziness

🚨 Serious Side Effects

Hypokalemia
Cardiac arrhythmias
Paradoxical bronchospasm

⚠️ Rare Side Effects

Allergic reactions
Seizures
Urinary retention

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major Hypertensive crisis
Beta-blockers Major Reduced bronchodilator effect
Other sympathomimetics Major Increased cardiovascular effects
Diuretics Moderate Hypokalemia
Corticosteroids Moderate Increased hypokalemia risk
Xanthine derivatives Moderate Increased CNS stimulation
Anticholinergics Minor Additive anticholinergic effects
Tricyclic antidepressants Minor Increased cardiovascular effects

🚨 Major Interactions

  • MAOIs
  • Beta-blockers
  • Other sympathomimetics

⚡ Moderate Interactions

  • Diuretics
  • Corticosteroids
  • Xanthine derivatives

🍷 Alcohol Interaction

Avoid alcohol as it may increase side effects

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, tachyarrhythmias, severe hypertension, hyperthyroidism

🤱 Lactation Safety

Caution; excreted in breast milk

💊 Overdose Management

Gastric lavage, activated charcoal, supportive measures; for severe symptoms, beta-blockers may be used cautiously

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

🔄 Substitutes for benelix br 50 mg/1.25 mg/4 mg syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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