becomed gm cream - Clobetasol (NA) + Miconazole (NA) medicine

becomed gm cream

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is becomed gm cream used for?

This medicine contains Clobetasol (NA) + Miconazole (NA) and is used to treat DERMA. Clobetasol: Anti-inflammatory via glucocorticoid receptor; Miconazole: Inhibits ergosterol synthesis. Always consult your doctor before use.

  • Generic Name: Clobetasol + Miconazole
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 becomed gm cream Uses & Benefits

Treatment of inflammatory dermatoses with fungal infection, e.g., tinea, candidiasis, eczema with secondary infection.

Off-label uses: Psoriasis, Lichen planus

📋 Drug Information

Generic Name(s)Clobetasol + Miconazole
Brand NameAgmaderm Cream
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassCorticosteroid + Antifungal
Route of AdministrationTopical
StorageStore at 20-25°C; avoid freezing.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPercutaneous absorption varies; increased with inflamed skin or occlusion.
DistributionDistributes locally; systemic absorption minimal with intact skin.
Protein BindingClobetasol: 96-99%; Miconazole: ~90%
MetabolismClobetasol: Hepatic via CYP3A4; Miconazole: Hepatic extensively.
Half-LifeClobetasol: ~2-3 hours; Miconazole: ~20-24 hours.
ExcretionClobetasol: Renal and biliary; Miconazole: Feces (major) and urine.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionWithin a few days of regular application.
Peak Plasma TimeNot well defined for topical; systemic peak varies.
Duration of ActionSustained effect with twice-daily application.

How It Works

Clobetasol: Anti-inflammatory via glucocorticoid receptor; Miconazole: Inhibits ergosterol synthesis disrupting fungal cell membrane.

Mechanism Steps

1Clobetasol binds to glucocorticoid receptor, modulating gene expression to reduce inflammation.
2Miconazole inhibits lanosterol 14α-demethylase, blocking ergosterol synthesis.
3Ergosterol depletion disrupts fungal cell membrane integrity, leading to cell death.

💡 How to Take becomed gm cream

Follow your doctor's prescription exactly.

⚠️ Side Effects of becomed gm cream

✅ Common Side Effects

Burning
Itching
Irritation
Dryness

🚨 Serious Side Effects

Adrenal suppression
Cushing's syndrome
Skin atrophy
Allergic contact dermatitis

⚠️ Rare Side Effects

Perioral dermatitis
Hypertrichosis
Hypopigmentation

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Ketoconazole Major Increased systemic corticosteroid effects
Insulin Moderate May alter blood glucose levels

🚨 Major Interactions

  • CYP3A4 inhibitors
  • Anticoagulants

⚡ Moderate Interactions

  • Antidiabetic agents
  • Diuretics

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to components; untreated bacterial or viral infections; rosacea; perioral dermatitis.

🤱 Lactation Safety

Use with caution; avoid application to breast area.

💊 Overdose Management

Acute overdose unlikely; chronic overuse may cause systemic corticosteroid effects; treat symptomatically.

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

🔄 Substitutes for becomed gm cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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