baselide plus oral suspension - Nimesulide (50mg/5ml) + Paracetamol (125mg/5ml) medicine

baselide plus oral suspension - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Ultramark Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is baselide plus oral suspension used for?

AP 100mg/325mg Tablet (Nimesulide + Paracetamol) is used to treat PAIN ANALGESICS. It contains Nimesulide (50mg/5ml) + Paracetamol (125mg/5ml), which Nimesulide selectively inhibits COX-2, reducing prostaglandin synthesis; Paracet. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Nimesulide + Paracetamol
  • Manufacturer: Ultramark Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š baselide plus oral suspension Uses & Benefits

Acute pain, fever, inflammatory conditions

Off-label uses: Dysmenorrhea, dental pain

๐Ÿ“‹ Drug Information

Generic Name(s)Nimesulide + Paracetamol
Brand NameAP 100mg/325mg Tablet
ManufacturerUltramark Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed; crosses placenta and enters breast milk
Protein BindingNimesulide: >97.5%; Paracetamol: 10-25%
MetabolismNimesulide: Hepatic via CYP2C9; Paracetamol: Hepatic via glucuronidation, sulfation, and CYP2E1
Half-LifeNimesulide: 1.8-4.7 hours; Paracetamol: 1.5-3 hours
ExcretionNimesulide: Renal (50%), fecal (29%); Paracetamol: Renal (90-100%)
BioavailabilityNimesulide: ~100%; Paracetamol: 60-90%
Onset of ActionNimesulide: 15-30 minutes; Paracetamol: 30-60 minutes
Peak Plasma TimeNimesulide: 1-3 hours; Paracetamol: 30-60 minutes
Duration of ActionNimesulide: 6-8 hours; Paracetamol: 4-6 hours

How It Works

Nimesulide selectively inhibits COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, reducing pain and fever

Mechanism Steps

1Nimesulide selectively inhibits COX-2 enzyme, reducing prostaglandin synthesis at sites of inflammation
2Paracetamol inhibits COX in the central nervous system, reducing pain and fever
3Decreased prostaglandins lead to reduced pain perception and inflammation

๐Ÿ’ก How to Take baselide plus oral suspension

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of baselide plus oral suspension

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Somnolence
  • Diarrhea

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Gastrointestinal bleeding
  • Stevens-Johnson syndrome
  • Renal failure

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Aspirin Major Increased risk of gastrointestinal ulceration
Other NSAIDs Major Additive gastrointestinal and renal toxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin
  • Other NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; avoid alcohol

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity and gastrointestinal bleeding

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, lactation, children <12 years (Nimesulide)

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, blood pressure, signs of bleeding

๐Ÿคฑ Lactation Safety

Paracetamol is safe; Nimesulide is contraindicated

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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