bactimax cream - Miconazole (2% w/w) + Mometasone (0.1% w/w) medicine

Afderm-MN Cream: Complete Guide to Uses, Dosage, and Safety

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🏭 Ajanta Pharma Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, hives, difficulty breathing, swelling of face, lips, tongue, or throat.
  • Signs of adrenal suppression: fatigue, weakness, nausea, low blood pressure.
  • Severe skin irritation, blistering, or peeling.
  • Signs of secondary infection: increased redness, swelling, pain, or pus.
  • No improvement after 2 weeks of use.
  • Symptoms worsen despite treatment.

If experiencing severe symptoms, call emergency services immediately.

What is bactimax cream used for?

This medicine is a topical cream combining miconazole (an antifungal) and mometasone (a corticosteroid). It treats fungal skin infections with associated inflammation, reducing itching, redness, and swelling. Apply a thin film to the affected area as directed by your doctor, usually once or twice daily. Do not use for more than 4 weeks without medical advice.

  • Generic Name: Miconazole + Mometasone
  • Manufacturer: Ajanta Pharma Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 bactimax cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें माइकोनाज़ोल और मोमेटासोन होते हैं। यह फंगल त्वचा संक्रमण के साथ-साथ सूजन, खुजली और लालिमा का इलाज करती है। इसे प्रभावित क्षेत्र पर पतली परत में लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर जलन, खुजली, या लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है। गंभीर दुष्प्रभावों में त्वचा का पतला होना, खिंचाव के निशान, और एड्रेनल सप्रेशन शामिल हैं।

सुरक्षा सलाह: केवल बाहरी उपयोग के लिए। आंखों, नाक, मुंह से संपर्क से बचें। डॉक्टर की सलाह के बिना चेहरे, जांघों या बगलों पर उपयोग न करें। निर्धारित अवधि से अधिक उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 bactimax cream Uses & Benefits

[{"condition":"Tinea corporis (ringworm of the body)","description":"Treats fungal infection of the body skin, reducing itching, redness, and scaling.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch)","description":"Treats fungal infection in the groin area, relieving itching and inflammation.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"Treats fungal infection of the feet, reducing itching, burning, and cracking.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis","description":"Treats yeast infections of the skin, often in skin folds.","evidence":"Well-established"},{"condition":"Tinea versicolor","description":"Treats fungal infection causing discolored patches on the skin.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Seborrheic dermatitis with fungal component","description":"Sometimes used when fungal elements are suspected, but not first-line.","evidence":"Limited"},{"condition":"Eczema with suspected fungal infection","description":"May be used if secondary fungal infection is present, but requires diagnosis.","evidence":"Limited"}]

Primary treatment for: Fungal skin infections with inflammation

Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Cutaneous candidiasis, Tinea versicolor

📋 Drug Information

Generic Name(s)Miconazole + Mometasone
Brand NameAfderm-MN Plus Cream
ManufacturerAjanta Pharma Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntifungal and Corticosteroid
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin film only to the affected area and surrounding skin; more is not better.
2
Wash your hands before and after application to prevent spreading the infection.
3
Do not use on the face, groin, or underarms unless specifically instructed by your doctor.
4
Complete the full course of treatment even if symptoms improve to prevent recurrence.
5
If the condition does not improve after 2 weeks, consult your doctor.
6
Avoid using airtight dressings over the treated area unless directed.
7
Inform your doctor if you are pregnant, breastfeeding, or planning pregnancy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Itchy, red, scaly rash in skin folds
This medicine is commonly prescribed for fungal infections like tinea cruris.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Bacterial skin infection with pus
This medicine is not effective against bacteria.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMiconazole is minimally absorbed through intact skin. Mometasone can be absorbed percutaneously, especially when applied to inflamed or damaged skin, or under occlusive dressings. Systemic absorption may lead to adrenal suppression if used extensively.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismMiconazole is metabolized in the liver, primarily by CYP3A4 and CYP2C9. Mometasone is metabolized in the liver, mainly by CYP3A4.
Half-LifeNot established from the available information.
ExcretionMiconazole and its metabolites are excreted mainly in feces and urine. Mometasone metabolites are excreted in urine and bile.
BioavailabilityNot established from the available information.
Onset of ActionSymptomatic relief of itching and inflammation may begin within hours to days. Antifungal effect requires several days to weeks of consistent use.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe anti-inflammatory effect lasts for several hours after application. The antifungal effect persists as long as the drug remains in the skin, but complete cure requires continued use for the prescribed duration.

How It Works

This medicine combines two active ingredients. Miconazole is an imidazole antifungal that inhibits the enzyme lanosterol 14α-demethylase, which is needed to convert lanosterol to ergosterol, a key component of the fungal cell membrane. This leads to increased permeability and leakage of cellular contents, causing fungal cell death. Mometasone is a synthetic corticosteroid that binds to glucocorticoid receptors in the cytoplasm, then translocates to the nucleus to modulate gene transcription. It reduces the production of inflammatory mediators such as prostaglandins and leukotrienes, and suppresses the migration of inflammatory cells, thereby reducing redness, swelling, itching, and pain.

Mechanism Steps

1
Miconazole inhibits ergosterol synthesis: Miconazole binds to and inhibits lanosterol 14α-demethylase, blocking the conversion of lanosterol to ergosterol, a vital component of the fungal cell membrane.
2
Fungal cell membrane disruption: The lack of ergosterol and accumulation of toxic sterol precursors weaken the fungal cell membrane, leading to leakage of intracellular contents and cell death.
3
Mometasone binds to glucocorticoid receptors: Mometasone diffuses into cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that translocates into the nucleus.
4
Modulation of gene transcription: The mometasone-receptor complex alters the transcription of genes involved in inflammation, reducing the production of pro-inflammatory cytokines and enzymes like COX-2.
5
Reduction of inflammation and itching: The overall effect is a decrease in inflammatory cells, reduced capillary permeability, and suppression of itching, providing symptomatic relief.

💡 How to Take bactimax cream

Strength: Cream containing miconazole 2% w/w and mometasone 0.1% w/w.

1Wash your hands thoroughly before and after applying the cream.
2Clean and dry the affected area gently.
3Apply a thin film of the cream to the affected area and surrounding skin.
4Gently rub it in until it disappears.
5Do not cover the area with a bandage or dressing unless instructed by your doctor.
6Avoid contact with eyes, nose, mouth, and other mucous membranes.
7Use as prescribed, usually once or twice daily.

Dosage Information

Adult DosageApply a thin film to the affected area and surrounding skin once or twice daily, or as directed by your doctor. The duration of treatment depends on the type and severity of the infection, typically 2 to 4 weeks. Do not use for more than 4 weeks without medical advice. Dose must be individualized by a qualified clinician based on indication, age, and response to treatment.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 2 years of age unless prescribed by a doctor.
Elderly DosageNo specific dose adjustments are required for elderly patients. However, they may be more susceptible to side effects. Use with caution and monitor for skin thinning and other local effects.
Renal ImpairmentNo dose adjustment is required for renal impairment when used topically, as systemic absorption is minimal.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment when used topically, as systemic absorption is minimal.
Maximum Daily DoseNot established from the available information. Use only as prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of bactimax cream

✅ Common Side Effects

Application site burning (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Application site itching (Common (1-10%))
May be due to the medicine or the condition. Consult if it worsens.
Application site redness (Common (1-10%))
Monitor. If it spreads or becomes painful, seek medical advice.
Skin dryness (Common (1-10%))
Use a moisturizer if needed, but avoid applying other products without consulting a doctor.

🚨 Serious Side Effects

Skin atrophy (thinning) (Uncommon (0.1-1%))
Stop use and consult a doctor if skin becomes thin, shiny, or easily bruised.
Stretch marks (striae) (Uncommon (0.1-1%))
Report to your doctor if you notice new stretch marks.
Adrenal suppression (Rare (<0.1%))
Seek medical attention if you experience fatigue, weakness, nausea, or low blood pressure.
Secondary infection (Uncommon (0.1-1%))
Consult a doctor if the treated area becomes more red, swollen, or painful.

⚠️ Rare Side Effects

Allergic contact dermatitis
Discontinue and seek medical help if you develop a rash, hives, or swelling.
Folliculitis
Consult a doctor if you notice inflamed hair follicles.
Hypertrichosis (excessive hair growth)
Report to your doctor if unwanted hair growth occurs.
Hypopigmentation
Consult a doctor if you notice lightening of the skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Ritonavir Major
Clarithromycin Major
Rifampin Moderate
Carbamazepine Moderate
Phenytoin Moderate
Warfarin Moderate
Sulfonylureas Moderate
Other topical corticosteroids Minor
Other topical antifungals Minor

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)

⚡ Moderate Interactions

  • Warfarin
  • Oral hypoglycemics (e.g., sulfonylureas)

🍷 Alcohol Interaction

No known interaction with alcohol when used topically. However, alcohol may worsen certain skin conditions. Consult your doctor.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to miconazole, mometasone, or any component of the formulation","Untreated bacterial or viral skin infections (e.g., herpes simplex, vaccinia, varicella)","Acne vulgaris, rosacea, perioral dermatitis","Use on the face, groin, or axillae unless directed by a doctor","Children under 2 years of age (unless prescribed)"]

⚠️ Warnings & Precautions

["For external use only. Do not ingest.","Avoid contact with eyes and mucous membranes.","Do not use on large areas or for prolonged periods without medical supervision.","Do not use under occlusive dressings unless instructed.","If irritation or sensitization occurs, discontinue use and consult a doctor.","Prolonged use may lead to skin thinning, stretch marks, and secondary infections.","Systemic absorption may occur, especially on broken skin; monitor for signs of adrenal suppression.","Consult a doctor if condition worsens or does not improve after 2 weeks.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether miconazole or mometasone pass into breast milk after topical application. However, systemic absorption is minimal. To be safe, do not apply to the breast area and consult your doctor before use while breastfeeding.

💊 Overdose Management

Topical overdose is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and signs of corticosteroid excess. Treatment is symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Wash your hands before and after applying the cream. Clean and dry the affected area before application. Apply a thin film and gently rub it in. Do not cover the treated area with airtight dressings unless instructed by your doctor. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use on the face, groin, or underarms unless specifically directed by a doctor. Do not use for more than the prescribed duration, as prolonged use increases the risk of side effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for any other skin condition without consulting a doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to skin thinning and other side effects. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Topical corticosteroids should be used with caution.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine on surgical wounds. It may interfere with wound healing and increase infection risk.

🦷 Dental Procedures

No specific considerations for dental procedures. However, inform your dentist if you are using this medicine.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or bedding.
😴
Wear loose, breathable clothing.
💧
Dry your skin thoroughly after bathing, especially in skin folds.
🧘
Avoid scratching the affected area to prevent spreading.
🌞
Maintain good hygiene to prevent reinfection.

🏋️ Exercise Considerations

No specific exercise restrictions. However, avoid activities that cause excessive sweating or friction on the affected area until it heals. Shower immediately after exercise and dry the area well.

🥗 Diet Recommendations

Eat a balanced diet to support immune function.
Include probiotics like yogurt to maintain healthy skin flora.
Stay hydrated.
Limit sugary and processed foods.

💼 Impact on Daily Work & Life

This medicine does not affect your ability to drive or operate machinery. You can continue your daily activities. However, if the infection is in an area that causes discomfort, you may need to take breaks or adjust your routine.

🛑 When to Stop This Medicine

Stop using this medicine after completing the prescribed course or as directed by your doctor. If you experience severe side effects, stop and consult your doctor immediately. Do not stop abruptly if you have been using it for a long time without medical advice.

📅 Long-Term Use Effects

Prolonged use of this medicine can lead to skin thinning, stretch marks, and increased risk of secondary infections. Systemic absorption of mometasone may cause adrenal suppression. Use for the shortest duration necessary and monitor for side effects. Regular review by a doctor is recommended if long-term use is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Keep the area clean and dry

Helps prevent fungal growth and supports healing.

Evidence: Well-established
Use of absorbent powders

Can reduce moisture in skin folds.

Evidence: Moderate
Wear breathable footwear

For athlete's foot, helps reduce moisture.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction with vaccines. However, if you are using this medicine over a large area or for a long time, consult your doctor before receiving live vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue your regular application schedule. Declare it at customs if required. Keep it in your carry-on luggage if you need it during the flight.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itchy, red rash in the groin area.
He was diagnosed with tinea cruris and prescribed this medicine. He applied it twice daily for 2 weeks. The itching reduced within 3 days, and the rash cleared completely after 2 weeks. He was advised to keep the area dry and avoid sharing towels.
💡 Lesson: Consistent application and good hygiene are key to treating fungal infections.
👤 A 50-year-old woman with athlete's foot and severe itching.
She used this medicine as directed for 4 weeks. The cracking and itching improved significantly. She was advised to wear breathable footwear and dry her feet thoroughly after washing.
💡 Lesson: Complete the full course and follow lifestyle measures to prevent recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Itching and redness may start to improve within a few days. The fungal infection typically clears within 2 to 4 weeks of consistent use.

Q: Can I use this cream on my face?

A: No, unless specifically directed by your doctor. It can cause skin thinning and other side effects on the face.

Q: Is it safe during pregnancy?

A: Consult your doctor before use. Topical corticosteroids should be used with caution during pregnancy.

Q: What if I miss a dose?

A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Can I stop using it when symptoms improve?

A: No, complete the full course as prescribed to prevent the infection from returning.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this cream on my face?
  • How long can I use this medicine?
  • Is it safe for children?
  • Can I use it during pregnancy?
  • What if I miss a dose?
  • Can I use it with other creams?

🔄 Substitutes for bactimax cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any skin rash.
    Fact: It is only effective for fungal infections with inflammation. It does not treat bacterial or viral infections.
  • Myth: More cream means faster healing.
    Fact: Applying more than a thin film does not speed up healing and may increase side effects.
  • Myth: You can stop using it as soon as symptoms improve.
    Fact: You must complete the full course to prevent the infection from returning.
  • Myth: It is safe to use on the face.
    Fact: It should not be used on the face unless specifically directed by a doctor, as it can cause skin thinning.

🔄 Alternative Options

Generic Alternatives

  • Miconazole + Mometasone cream (generic)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Miconazole + Mometasone","potency":"Medium","common_use":"Fungal infections with inflammation"},{"medicine":"Clotrimazole + Betamethasone","active_ingredients":"Clotrimazole + Betamethasone","potency":"Medium","common_use":"Fungal infections with inflammation"},{"medicine":"Ketoconazole + Hydrocortisone","active_ingredients":"Ketoconazole + Hydrocortisone","potency":"Low","common_use":"Fungal infections with mild inflammation"}]

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