azvin 500mg injection - Aztreonam (500mg) medicine

Azvin 500mg Injection - Uses, Price, Side Effects

4.6 (8 reviews)

Aztreonam (500mg)

🏭 Arvincare Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is azvin 500mg injection used for?

Azvin 500mg Injection contains Aztreonam, a monobactam antibiotic used to treat moderate to severe bacterial infections caused by susceptible gram-negative bacteria, including urinary tract, respiratory, intra-abdominal, and skin infections. It works by inhibiting bacterial cell wall synthesis.

Generic Name: Aztreonam
Manufacturer: Arvincare Pharma
Form: Allopathy
Pregnancy Category: B
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 azvin 500mg injection Uses & Benefits

Treatment of infections caused by susceptible Gram-negative bacteria including urinary tract infections, lower respiratory tract infections, septicemia, skin and skin structure infections, intra-abdominal infections, and gynecologic infections.

Off-label uses: Febrile neutropenia (in combination), Meningitis (with inflamed meninges)

📋 Drug Information

Generic Name(s)	Aztreonam
Brand Name	Azenam 1gm Injection
Manufacturer	Arvincare Pharma
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Monobactams
Route of Administration	Intravenous (IV) or intramuscular (IM) injection.
Storage	Store at 20-25°C (68-77°F); protect from light; reconstituted solutions stable for 48 hours at room temperature or 7 days under refrigeration.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration results in rapid and complete absorption; intravenous administration provides immediate systemic availability.

DistributionWidely distributed into body tissues and fluids including cerebrospinal fluid (with inflamed meninges), bile, sputum, and pleural fluid.

Protein BindingApproximately 56% bound to plasma proteins.

MetabolismMetabolized primarily by hydrolysis of the beta-lactam ring to inactive metabolites.

Half-LifeApproximately 1.7 hours in patients with normal renal function; prolonged in renal impairment.

ExcretionPrimarily excreted unchanged in urine (60-70%) via glomerular filtration and tubular secretion; small amount in feces.

Bioavailability100% (intravenous); approximately 100% (intramuscular).

Onset of ActionRapid; within 30 minutes after intravenous administration.

Peak Plasma TimeIntravenous: immediately after infusion; intramuscular: 1 hour.

Duration of ActionApproximately 6-8 hours depending on renal function.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding protein 3 (PBP3), leading to cell lysis and death.

Mechanism Steps

1Aztreonam binds to penicillin-binding protein 3 (PBP3) on the inner membrane of Gram-negative bacteria.

2Inhibition of PBP3 prevents transpeptidation, a key step in peptidoglycan cross-linking.

3Disruption of cell wall synthesis leads to osmotic instability and bacterial cell lysis.

💡 How to Take azvin 500mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of azvin 500mg injection

✅ Common Side Effects

Injection site reactions (pain, phlebitis)
Diarrhea
Nausea
Vomiting
Rash

🚨 Serious Side Effects

Severe hypersensitivity reactions (anaphylaxis)
Clostridioides difficile-associated diarrhea
Seizures
Hepatotoxicity

⚠️ Rare Side Effects

Pseudomembranous colitis
Blood dyscrasias (neutropenia, thrombocytopenia)
Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Moderate	Increased bleeding risk
Probenecid	Moderate	Decreased renal excretion of aztreonam
Aminoglycosides	Moderate	Additive nephrotoxicity

🚨 Major Interactions

Warfarin
Live Typhoid Vaccine
BCG Vaccine

⚡ Moderate Interactions

Probenecid
Aminoglycosides
Furosemide

ℹ️ Minor Interactions

Chloramphenicol
Tetracyclines

🍽️ Food Interactions

No significant food interactions; injection only.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver

Low

Kidney

Moderate

Heart

Low

Pregnancy

Category B

🚫 Contraindications

Hypersensitivity to aztreonam or any component of the formulation.

📊 Monitoring Parameters

Renal function (especially in elderly or with concurrent nephrotoxic drugs), liver function tests, signs of hypersensitivity, and superinfection.

🤱 Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Administer as soon as possible; if near next dose, skip missed dose and resume regular schedule.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for azvin 500mg injection

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Alternative brands with exact same active ingredient (Aztreonam (500mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026