azpar iv infusion - Paracetamol (1000mg) medicine

Azpar IV Infusion (Paracetamol 1000mg) - Uses, Price, Side Effects

4.4 (12 reviews)

Paracetamol (1000mg)

🏭 ADZO Lifesciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is azpar iv infusion used for?

Azpar IV Infusion contains Paracetamol 1000mg, a pain reliever and fever reducer. It works by blocking chemical messengers that cause pain and fever in the brain. It is used for short-term treatment of moderate pain and fever, especially when oral administration is not possible.

Generic Name: Paracetamol
Manufacturer: ADZO Lifesciences Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 azpar iv infusion Uses & Benefits

Mild to moderate pain (headache, dental pain, dysmenorrhea, osteoarthritis); fever.

Off-label uses: Patent ductus arteriosus closure in neonates (IV form); osteoarthritis pain.

📋 Drug Information

Generic Name(s)	Paracetamol
Brand Name	Action or 1000mg Tablet
Manufacturer	ADZO Lifesciences Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	Analgesic & Antipyretic-PCM
Route of Administration	Oral
Storage	Store at room temperature (15-30°C); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.

DistributionWidely distributed throughout body fluids; crosses placenta and appears in breast milk.

Protein Binding10-25%

MetabolismHepatic via conjugation (glucuronidation and sulfation); minor oxidation via CYP2E1.

Half-Life1.5-3 hours

ExcretionRenal (90-100% as metabolites within 24 hours).

Bioavailability75-85%

Onset of Action30-60 minutes

Peak Plasma Time30-60 minutes

Duration of Action4-6 hours

How It Works

Inhibits cyclooxygenase (COX) in the central nervous system, reducing prostaglandin synthesis; also activates descending serotonergic pathways.

Mechanism Steps

1Inhibition of COX-1 and COX-2 in the central nervous system

2Reduction of prostaglandin synthesis in the hypothalamus

3Activation of descending serotonergic pathways

💡 How to Take azpar iv infusion

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of azpar iv infusion

✅ Common Side Effects

Nausea
Vomiting
Constipation
Rash

🚨 Serious Side Effects

Hepatotoxicity
Acute liver failure
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Acute generalized exanthematous pustulosis

⚠️ Rare Side Effects

Thrombocytopenia
Leukopenia
Neutropenia
Pancreatitis
Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Alcohol	Moderate	Increased risk of liver toxicity
Carbamazepine	Moderate	Decreased paracetamol efficacy

🚨 Major Interactions

Warfarin
Alcohol (chronic heavy use)
Isoniazid
Rifampin
Carbamazepine
Phenytoin
Barbiturates

⚡ Moderate Interactions

Cholestyramine
Metoclopramide
Domperidone
Probenecid
Oral contraceptives

ℹ️ Minor Interactions

Caffeine
Zidovudine
Lamotrigine

🍽️ Food Interactions

Food may delay absorption; high-fat meals reduce peak concentration.

🍷 Alcohol Interaction

Chronic heavy alcohol use increases hepatotoxicity risk; avoid concurrent use.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to paracetamol; severe hepatic impairment; chronic alcoholism.

📊 Monitoring Parameters

Liver function tests (in overdose or chronic high doses); renal function in long-term use.

🤱 Lactation Safety

Excreted in breast milk in small amounts; considered safe at therapeutic doses.

💊 Overdose Management

Activated charcoal if within 1 hour; N-acetylcysteine (NAC) as antidote; monitor liver function.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for azpar iv infusion

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Alternative brands with exact same active ingredient (Paracetamol (1000mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026