azox p 0.25mg/10mg tablet - Alprazolam (0.25mg) + Propranolol (10mg) medicine

azox p 0.25mg/10mg tablet

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🏭 Aarpik Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is azox p 0.25mg/10mg tablet used for?

This medicine contains Alprazolam (0.25mg) + Propranolol (10mg) and is used to treat NEURO CNS. Alprazolam enhances GABA-A receptor activity; Propranolol blocks beta-adrenergic receptors. Always consult your doctor before use.

  • Generic Name: Alprazolam + Propranolol
  • Manufacturer: Aarpik Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 azox p 0.25mg/10mg tablet Uses & Benefits

Anxiety disorders, panic disorder, performance anxiety, essential tremor, situational anxiety

Off-label uses: Insomnia, premenstrual dysphoric disorder, social phobia, migraine prophylaxis

📋 Drug Information

Generic Name(s)Alprazolam + Propranolol
Brand NameAmbulax Tablet
ManufacturerAarpik Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepine + Beta-blocker
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely; crosses blood-brain barrier
Protein BindingAlprazolam: 80%; Propranolol: >90%
MetabolismHepatic via CYP3A4 (alprazolam) and CYP2D6 (propranolol)
Half-LifeAlprazolam: 6-12 hours; Propranolol: 3-6 hours
ExcretionRenal (urine)
BioavailabilityAlprazolam: 90%; Propranolol: 25-30%
Onset of ActionAlprazolam: 1-2 hours; Propranolol: 1-2 hours
Peak Plasma TimeAlprazolam: 1-2 hours; Propranolol: 1-4 hours
Duration of ActionAlprazolam: 6-12 hours; Propranolol: 6-12 hours

How It Works

Alprazolam enhances GABA-A receptor activity; Propranolol blocks beta-adrenergic receptors

Mechanism Steps

1Alprazolam binds to benzodiazepine site on GABA-A receptor
2Enhances GABA affinity, increasing chloride ion influx
3Hyperpolarizes neuron, reducing excitability
4Propranolol competitively blocks beta-1 and beta-2 adrenergic receptors
5Reduces sympathetic outflow, decreasing heart rate and contractility
6Lowers blood pressure and attenuates physical symptoms of anxiety

💡 How to Take azox p 0.25mg/10mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of azox p 0.25mg/10mg tablet

✅ Common Side Effects

Drowsiness
Dizziness
Fatigue
Dry mouth
Nausea
Constipation
Bradycardia
Hypotension

🚨 Serious Side Effects

Respiratory depression
Severe bradycardia
Heart block
Hypotension
Seizures
Suicidal thoughts
Anaphylaxis

⚠️ Rare Side Effects

Jaundice
Agranulocytosis
Thrombocytopenia
Stevens-Johnson syndrome
Bronchospasm

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major Increased alprazolam levels and toxicity
Quinidine Major Increased propranolol levels and bradycardia
Alcohol Major Enhanced CNS depression and sedation
Warfarin Moderate Possible increased INR
Digoxin Moderate Increased risk of bradycardia

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP2D6 inhibitors (e.g., quinidine)
  • Other CNS depressants
  • Calcium channel blockers
  • Antiarrhythmics

⚡ Moderate Interactions

  • Oral hypoglycemics
  • Theophylline
  • Warfarin
  • Digoxin
  • MAO inhibitors

🍷 Alcohol Interaction

Avoid; increased CNS depression and sedation

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, acute narrow-angle glaucoma, severe COPD, asthma, bradycardia, heart block, uncompensated heart failure, myasthenia gravis, severe hepatic impairment

🤱 Lactation Safety

Not recommended; both drugs excreted in breast milk

💊 Overdose Management

Supportive care; flumazenil for alprazolam overdose; atropine, beta-agonists for propranolol overdose

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

🔄 Substitutes for azox p 0.25mg/10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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