Azop Plus 6mg/400mg Tablet - Uses, Price, Side Effects
What is azop plus 6mg/400mg tablet used for?
Azop Plus 6mg/400mg Tablet is a combination of Ivermectin and Albendazole used to treat parasitic infections like strongyloidiasis, filariasis, and hydatid disease. Ivermectin paralyzes and kills parasites, while Albendazole inhibits their glucose uptake, leading to energy depletion and death.
- Generic Name: Ivermectin + Albendazole
- Manufacturer: Alpic Biotech Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ azop plus 6mg/400mg tablet Uses & Benefits
Filariasis, strongyloidiasis, ascariasis, hookworm, trichuriasis, enterobiasis
Off-label uses: Scabies, lice, cutaneous larva migrans
๐ Drug Information
| Generic Name(s) | Ivermectin + Albendazole |
| Brand Name | ABD Plus Tablet |
| Manufacturer | Alpic Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Anthelmintics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells, causing hyperpolarization and paralysis; Albendazole: inhibits tubulin polymerization, disrupting microtubule formation and glucose uptake
Mechanism Steps
๐ก How to Take azop plus 6mg/400mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of azop plus 6mg/400mg tablet
โ Common Side Effects
- Nausea
- vomiting
- diarrhea
- abdominal pain
- headache
- dizziness
๐จ Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- agranulocytosis
- seizures
โ ๏ธ Rare Side Effects
- Alopecia
- acute renal failure
- pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased bleeding risk |
| Theophylline | Moderate | Increased theophylline levels |
| Cimetidine | Minor | Increased albendazole levels |
๐จ Major Interactions
- Warfarin
- Theophylline
- CYP3A4 inhibitors (e.g., ketoconazole)
โก Moderate Interactions
- CYP3A4 inducers (e.g., rifampin)
- P-glycoprotein inhibitors
โน๏ธ Minor Interactions
- Grapefruit juice
๐ฝ๏ธ Food Interactions
Fatty meal increases absorption of albendazole; avoid grapefruit juice
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, pregnancy, lactation, hepatic impairment
๐ Monitoring Parameters
Liver function tests, renal function, blood counts
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage if recent
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose