azipark lb 250mg tablet - Azithromycin (250mg) + Lactic acid bacillus (60Million spores) medicine

Azirop-LB Tablet: Comprehensive Medicine Guide

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🏭 Park Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing.
  • Signs of liver injury: yellowing of skin or eyes, dark urine, severe abdominal pain, unusual fatigue.
  • Irregular heartbeat: palpitations, dizziness, fainting.
  • Severe or bloody diarrhea, which may indicate Clostridium difficile infection.
  • Decreased urine output or swelling, which may indicate kidney problems.
  • Persistent headache with visual changes.
  • High fever that does not improve after 48 hours of treatment.

If experiencing severe symptoms, call emergency services immediately.

What is azipark lb 250mg tablet used for?

This medicine is a combination of azithromycin, an antibiotic, and lactic acid bacillus, a probiotic. It is used to treat bacterial infections of the respiratory tract, skin, and sexually transmitted infections. The probiotic helps prevent diarrhea caused by antibiotics.

  • Generic Name: Azithromycin + Lactic acid bacillus
  • Manufacturer: Park Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 azipark lb 250mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एज़िथ्रोमाइसिन और लैक्टिक एसिड बैसिलस का संयोजन है। इसका उपयोग श्वसन पथ, त्वचा और यौन संचारित संक्रमणों के इलाज के लिए किया जाता है। एज़िथ्रोमाइसिन बैक्टीरिया को मारता है और लैक्टिक एसिड बैसिलस पेट के अच्छे बैक्टीरिया को बनाए रखने में मदद करता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लीवर की समस्या और अनियमित दिल की धड़कन हो सकती है। यदि आपको लगातार दस्त, पीलिया या धड़कन महसूस हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे दूसरों के साथ साझा न करें। अपने डॉक्टर को अन्य दवाओं के बारे में बताएं। इलाज के दौरान शराब से बचें। खुराक भूल जाने पर याद आते ही ले लें, लेकिन अगली खुराक के करीब हो तो छोड़ दें। दोहरी खुराक न लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 azipark lb 250mg tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat mild to moderate pneumonia caused by susceptible bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"Effective against sinus infections caused by Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Prescribed for flare-ups of chronic bronchitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Pharyngitis/tonsillitis","description":"Used as an alternative to penicillin for streptococcal pharyngitis in patients allergic to penicillin.","evidence":"Well-established"},{"condition":"Uncomplicated skin and skin structure infections","description":"Treats infections such as cellulitis, impetigo, and erysipelas caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urethritis and cervicitis","description":"Used to treat sexually transmitted infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Bronchiolitis obliterans syndrome","description":"Sometimes used in lung transplant patients to prevent or treat chronic rejection.","evidence":"Limited"},{"condition":"Cystic fibrosis","description":"May be used to reduce lung inflammation and improve lung function in some patients.","evidence":"Limited"},{"condition":"Malaria","description":"Used in combination with other antimalarials for treatment of uncomplicated malaria.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Community-acquired pneumonia, Acute bacterial sinusitis, Pharyngitis, Skin infections, Urethritis, Cervicitis

📋 Drug Information

Generic Name(s)Azithromycin + Lactic acid bacillus
Brand NameAzital-LB 500 Tablet
ManufacturerPark Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassMacrolide antibiotic + Probiotic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineAzithromycin is included in the WHO Model List of Essential Medicines for the treatment of various bacterial infections, including sexually transmitted infections and respiratory tract infections.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) recommends azithromycin for the treatment of community-acquired pneumonia, enteric fever, and certain sexually transmitted infections, based on local resistance patterns.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Complete the full prescribed course even if you start feeling better after a few doses.
3
Take with food if it upsets your stomach, but avoid taking antacids within 2 hours.
4
Inform your doctor if you have a history of heart rhythm problems or liver disease.
5
Avoid alcohol during treatment to reduce the risk of stomach upset and liver strain.
6
Report any severe or persistent diarrhea, as it may indicate a serious gut infection.
7
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Throat infection
This medicine is commonly prescribed for bacterial pharyngitis.
Likely Use
✅
Skin infection
Used for uncomplicated skin infections like cellulitis.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary
❌
Fever
This medicine is not a primary fever reducer; it treats the underlying bacterial infection.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAzithromycin is rapidly absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 37% due to first-pass metabolism. Food may slightly delay absorption but does not significantly affect the extent of absorption.
DistributionAzithromycin distributes widely throughout the body, with high concentrations in tissues such as lungs, tonsils, and prostate. It accumulates in phagocytes and is transported to sites of infection. Protein binding is low, ranging from 7% to 50% depending on serum concentration.
Protein BindingAzithromycin is approximately 7% to 50% bound to serum proteins, depending on concentration.
MetabolismAzithromycin undergoes limited hepatic metabolism, primarily via N-demethylation and O-demethylation, but the exact metabolic pathways are not fully characterized.
Half-LifeThe terminal elimination half-life of azithromycin is approximately 68 hours, allowing for once-daily dosing and a 3-day or 5-day course.
ExcretionAzithromycin is primarily excreted unchanged in bile, with about 6% of an oral dose excreted in urine. Lactic acid bacillus is excreted in feces.
BioavailabilityThe oral bioavailability of azithromycin is approximately 37%.
Onset of ActionClinical improvement in infections may be seen within 24 to 48 hours, but full effect depends on the infection and immune response.
Peak Plasma TimePeak plasma concentrations of azithromycin are reached approximately 2 to 3 hours after oral administration.
Duration of ActionDue to its long half-life and tissue accumulation, azithromycin's effects persist for several days after the last dose, allowing for short-course therapy.

How It Works

Azithromycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Lactic acid bacillus is a probiotic that helps restore and maintain beneficial gut flora, which may be disrupted by antibiotic therapy.

Mechanism Steps

1
Binding to ribosomal subunit: Azithromycin binds to the 50S subunit of the bacterial ribosome, specifically to the 23S rRNA component.
2
Inhibition of protein synthesis: This binding blocks the translocation step of protein synthesis, preventing the addition of new amino acids to the growing peptide chain.
3
Bacterial growth arrest: As a result, bacteria cannot synthesize essential proteins and their growth is halted, allowing the immune system to clear the infection.
4
Probiotic effect: Lactic acid bacillus spores germinate in the intestine and produce lactic acid, creating an environment that favors beneficial bacteria and inhibits harmful ones.

💡 How to Take azipark lb 250mg tablet

Strength: Azithromycin 250 mg + Lactic acid bacillus 60 million spores immediate-release tablet.

1Take this medicine by mouth with a glass of water.
2You may take it with or without food.
3Swallow the tablet whole; do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Complete the full prescribed course even if you feel better.
6Do not take antacids within 2 hours of this medicine.

Dosage Information

Adult DosageThe usual adult dose for most infections is 500 mg on the first day, followed by 250 mg once daily on days 2 to 5. For certain infections, a single 1 g dose may be used. For sexually transmitted infections, a single 1 g dose is often prescribed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to side effects such as QT prolongation and hearing loss. Dose adjustment may be needed based on renal function. Consult a doctor.
Renal ImpairmentNo dose adjustment is generally needed for mild to moderate renal impairment. In severe renal impairment (GFR <10 mL/min), use with caution and monitor closely.
Hepatic ImpairmentNo dose adjustment is recommended for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment.
Maximum Daily DoseThe maximum recommended daily dose is 500 mg for most indications, but a single 1 g dose may be used for certain infections.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
May take with or without food
Food does not affect absorption but can reduce stomach upset.
Antacids
Avoid taking together
Antacids can reduce peak levels of azithromycin.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of azipark lb 250mg tablet

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it interferes with eating.
Abdominal pain (Common (5-10%))
Take with food. Consult doctor if pain is severe or persistent.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or unusual.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face/lips/tongue, difficulty breathing.
Liver damage (hepatotoxicity) (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, severe abdominal pain, or fatigue.
Irregular heart rhythm (QT prolongation) (Rare (<0.1%))
Seek immediate care if you experience palpitations, dizziness, or fainting.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek medical attention if you develop severe, persistent diarrhea, especially with blood or mucus.

⚠️ Rare Side Effects

Torsades de pointes
Seek emergency care if you experience fainting or irregular heartbeat.
Pancreatitis
Seek medical attention if you have severe abdominal pain radiating to back.
Interstitial nephritis
Seek medical attention if you notice decreased urine output or swelling.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ergotamine Major
Amiodarone Major
Antacids Moderate
Digoxin Moderate
Cyclosporine Moderate
Carbamazepine Minor
Phenytoin Minor

🚨 Major Interactions

  • Warfarin
  • Ergotamine
  • Amiodarone

⚡ Moderate Interactions

  • Antacids (aluminum or magnesium based)
  • Digoxin
  • Cyclosporine

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach upset and liver problems. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to azithromycin, erythromycin, or any macrolide antibiotic","History of cholestatic jaundice or hepatic dysfunction associated with prior azithromycin use","Concurrent use with ergotamine or dihydroergotamine"]

⚠️ Warnings & Precautions

["Serious allergic reactions, including anaphylaxis, can occur. Discontinue and seek immediate care if suspected.","Hepatotoxicity: Discontinue if signs of liver injury occur.","QT prolongation: Use with caution in patients with risk factors.","Clostridium difficile-associated diarrhea: May occur; monitor if diarrhea develops.","Superinfection: Prolonged use may lead to overgrowth of non-susceptible organisms.","Renal impairment: Use with caution; dose adjustment may be needed.","Myasthenia gravis: May exacerbate symptoms."]

🤱 Lactation Safety

Azithromycin is excreted in breast milk in small amounts and is generally considered safe during breastfeeding. Consult your doctor to weigh benefits and risks.

💊 Overdose Management

Overdose may cause severe nausea, diarrhea, and hearing loss. Treatment is symptomatic and supportive. Contact a poison control center or emergency room immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others. Inform your doctor about all other medicines you are taking, especially antacids, warfarin, and other antibiotics. Avoid alcohol during treatment. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects such as QT prolongation, hearing loss, and liver problems. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. Azithromycin is generally considered safe, but the benefits and risks should be weighed.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon about this medicine. It may interact with anesthetics or other medications used during surgery. Your doctor may advise stopping it before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures. No specific precautions are usually needed, but good communication is important.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help your body clear the infection.
🥗
Get plenty of rest to support your immune system.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hand hygiene to prevent spreading infections.
🧘
Avoid close contact with others while you are contagious.
🌞
Complete the full course of antibiotics as prescribed.

🏋️ Exercise Considerations

You may continue light exercise if you feel up to it, but avoid strenuous activities if you have fever or fatigue. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to support gut health.
Stay hydrated with water and clear fluids.
Avoid spicy and oily foods if you have stomach upset.
Eat small, frequent meals if you have nausea.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you experience these effects. Most people can continue their normal activities, but rest is important for recovery.

🛑 When to Stop This Medicine

Do not stop taking this medicine early unless your doctor advises you to. Complete the full prescribed course to prevent recurrence and resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of azithromycin is not recommended unless specifically prescribed for chronic conditions. Prolonged use may lead to bacterial resistance, gut flora imbalance, and rare side effects like hearing loss or liver problems. Regular monitoring may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and resistance patterns, other antibiotics like amoxicillin or clarithromycin may be used.

Evidence: Well-established
Probiotic supplements

Can be taken separately to maintain gut health during antibiotic therapy.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics like azithromycin do not interact with vaccines. However, if you are acutely ill with fever, vaccination may be deferred until you recover. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually to maintain consistent intervals. Check customs regulations for carrying prescription medicines. Keep a list of your medications with you at all times.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with acute bacterial sinusitis
She was prescribed this medicine for 5 days. She took it with food to avoid stomach upset and completed the full course. Her symptoms improved within 3 days, and she did not experience any diarrhea thanks to the probiotic component.
💡 Lesson: Taking the full course and using the probiotic combination can improve outcomes and reduce side effects.
👤 A 50-year-old man with community-acquired pneumonia
He was started on this medicine and advised to avoid alcohol. He initially felt better after 2 days but continued the full course as directed. His infection resolved completely, and he had no recurrence.
💡 Lesson: Completing the full antibiotic course is essential to prevent relapse and resistance, even if symptoms improve early.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe during pregnancy?

A: Azithromycin is generally considered safe during pregnancy when clearly needed, but consult your doctor before taking any medicine.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may increase the risk of stomach upset and liver problems.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for azipark lb 250mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: Antibiotics only work against bacteria. This medicine is not effective for viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full prescribed course to prevent bacterial resistance and relapse.
  • Myth: Probiotics in antibiotics are unnecessary.
    Fact: Probiotics like lactic acid bacillus help maintain gut health and reduce antibiotic-associated diarrhea.

🔄 Alternative Options

Generic Alternatives

  • Azithromycin 250 mg + Lactic acid bacillus 60 million spores tablet

Brand Alternatives

  • Azee-LB
  • Azithral-LB
  • Zithrox-LB

📊 Comparison with Similar Medicines

[{"medicine":"Azirop-LB","composition":"Azithromycin 250 mg + Lactic acid bacillus 60 million spores","key_feature":"Combination with probiotic"},{"medicine":"Azithromycin alone","composition":"Azithromycin 250 mg","key_feature":"Antibiotic only"},{"medicine":"Clarithromycin","composition":"Clarithromycin 250 mg","key_feature":"Different macrolide antibiotic"}]

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