Azilura 40 Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe dizziness, fainting, or lightheadedness.
- Decreased urine output or swelling in the legs or feet.
- Irregular heartbeat or muscle weakness (signs of high potassium).
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Chest pain or shortness of breath.
- Severe headache with visual changes.
If experiencing severe symptoms, call emergency services immediately.
What is azilura 40 tablet used for?
Azilura 40 tablet contains azilsartan medoxomil 40 mg, an angiotensin II receptor blocker used to treat high blood pressure in adults. It works by relaxing blood vessels, allowing blood to flow more easily. It is taken once daily, with or without food, and should not be used during pregnancy.
- Generic Name: Azilsartan medoxomil (40mg)
- Manufacturer: MSN Laboratories
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 azilura 40 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एज़िलसार्टन मेडोक्सोमिल 40 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है और हृदय तथा गुर्दे पर पड़ने वाले दबाव को घटाती है। यह दवा दिल के दौरे, स्ट्रोक और गुर्दे की बीमारी के खतरे को कम करने में मदद करती है। इसे आमतौर पर दिन में एक बार खाया जाता है, भोजन के साथ या बिना। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए क्योंकि यह शिशु के लिए हानिकारक हो सकती है। इस दवा को डॉक्टर की सलाह के बिना बंद या शुरू न करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और हल्का जी मिचलाना शामिल हैं। कुछ लोगों में पैरों में सूजन, मांसपेशियों में ऐंठन या दाने भी हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि चेहरे, होंठ, जीभ या गले में सूजन आए, सांस लेने में कठिनाई हो, बहुत अधिक चक्कर आए या पेशाब कम आए, तो तुरंत डॉक्टर से संपर्क करें। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और पोटैशियम की जांच कराते रहें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में एक बार। इसे अचानक बंद न करें, क्योंकि इससे रक्तचाप फिर बढ़ सकता है। शराब से बचें क्योंकि इससे चक्कर और कम रक्तचाप हो सकता है। पोटैशियम सप्लीमेंट या नमक के विकल्प डॉक्टर की सलाह के बिना न लें। गर्भवती या गर्भधारण की योजना बना रही महिलाएं तुरंत डॉक्टर को बताएं। दवा को कमरे के तापमान पर, मूल डिब्बे में, नमी और धूप से दूर रखें। बच्चों की पहुंच से दूर रखें।
💊 azilura 40 tablet Uses & Benefits
- [{"condition":"Hypertension (high blood pressure)","description":"This medicine is used to lower blood pressure in adults, either alone or in combination with other antihypertensive agents.
- It helps reduce the risk of cardiovascular events such as stroke and heart attack.","evidence":"Well-established"},{"condition":"Hypertension with chronic kidney disease","description":"May be used in patients with high blood pressure and kidney disease to help control blood pressure and slow kidney damage, but dose adjustment and monitoring are needed.","evidence":"Moderate"},{"condition":"Hypertension in patients with type 2 diabetes","description":"Can be used to manage blood pressure in diabetic patients, often as part of a comprehensive cardiovascular risk reduction plan.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Heart failure with reduced ejection fraction","description":"Sometimes considered as an alternative to other angiotensin receptor blockers in patients who cannot tolerate them, but this is not a standard approved use for azilsartan.","evidence":"Limited"},{"condition":"Diabetic nephropathy","description":"May be used off-label to reduce proteinuria in diabetic kidney disease, though other agents are more commonly used.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Chronic kidney disease, Type 2 diabetes mellitus, Heart failure (off-label)
📋 Drug Information
| Generic Name(s) | Azilsartan medoxomil (40mg) |
| Brand Name | azilura 40 tablet |
| Manufacturer | MSN Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin receptor blockers(ARB) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, tightly closed, away from moisture and direct sunlight. Do not refrigerate. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively blocking the angiotensin II type 1 (AT1) receptor. Angiotensin II is a hormone that causes blood vessels to narrow and also stimulates the release of aldosterone, which leads to sodium and water retention. By blocking the AT1 receptor, this medicine prevents these effects, resulting in relaxation of blood vessels, reduced aldosterone secretion, and decreased sodium and water retention. This leads to lower blood pressure and reduced workload on the heart. Unlike ACE inhibitors, this medicine does not affect bradykinin levels, so it is less likely to cause a dry cough.
Mechanism Steps
💡 How to Take azilura 40 tablet
Strength: Immediate-release tablet, 40 mg.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine for high blood pressure is 40 mg once daily, and the dose may be increased to 80 mg once daily if needed. It can be taken with or without food. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No dose adjustment is required based on age alone. However, elderly patients may be more sensitive to the blood pressure-lowering effects and should be monitored for dizziness and falls. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No initial dose adjustment is required for mild to moderate renal impairment. For severe renal impairment or end-stage renal disease, use with caution and monitor kidney function and potassium levels. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No dose adjustment is required for mild to moderate hepatic impairment. In severe hepatic impairment, use is not recommended. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 80 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of azilura 40 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aliskiren | Major | |
| Spironolactone | Major | |
| Lithium | Major | |
| Ibuprofen | Major | |
| Naproxen | Major | |
| Furosemide | Moderate | |
| Hydrochlorothiazide | Moderate | |
| Fluconazole | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Aliskiren
- Potassium-sparing diuretics (e.g., spironolactone, triamterene)
- Lithium
- NSAIDs (e.g., ibuprofen, naproxen)
⚡ Moderate Interactions
- Diuretics
- Other antihypertensives
- CYP2C9 inhibitors (e.g., fluconazole)
🍷 Alcohol Interaction
Alcohol can enhance the blood pressure-lowering effect of this medicine and increase the risk of dizziness, lightheadedness, and fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to azilsartan medoxomil or any component of the formulation","Pregnancy","Severe liver impairment or biliary obstruction","Concomitant use with aliskiren in patients with diabetes","History of angioedema with other angiotensin receptor blockers"]
⚠️ Warnings & Precautions
["This medicine can cause fetal harm when administered to a pregnant woman. Discontinue as soon as pregnancy is detected.","May cause symptomatic hypotension, especially in volume-depleted patients. Correct volume depletion before starting.","Monitor kidney function and potassium levels periodically, especially in patients with kidney disease or diabetes.","Avoid use with potassium supplements or potassium-sparing diuretics without monitoring.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Not recommended in patients with severe liver disease.","Use with caution in patients with aortic or mitral stenosis, or hypertrophic cardiomyopathy."]
🤱 Lactation Safety
It is not known whether azilsartan is excreted in human breast milk. Because of the potential for adverse effects in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
Overdose may cause severe hypotension, dizziness, and fainting. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive, including placing the patient in a supine position and giving intravenous fluids if needed. Hemodialysis is not expected to remove azilsartan from the blood.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily, with or without food. Do not stop taking it suddenly, because blood pressure may rise again. Keep a record of your blood pressure readings and bring them to your follow-up visits. Avoid alcohol, as it can increase dizziness and lower blood pressure too much. Do not use potassium supplements or salt substitutes containing potassium without asking your doctor, because this medicine can raise potassium levels. Tell your doctor about all other medicines you take, especially pain relievers, diuretics, lithium, and other blood pressure drugs. If you have kidney or liver disease, your doctor may need to adjust your dose or monitor you more closely. Women who are pregnant or planning pregnancy must inform their doctor immediately, as this medicine can harm the baby. Store the tablets in their original container at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Monitor blood pressure regularly and rise slowly from sitting or lying positions. Dose adjustment is not usually needed based on age alone, but individualization is important.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. Women planning pregnancy should consult their doctor to switch to a safer alternative before conception. If pregnancy occurs while taking this medicine, stop it immediately and contact your doctor.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid excessive blood pressure drop during the procedure. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Maintain good oral hygiene and follow your dentist's advice regarding any precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is beneficial for blood pressure control, but avoid sudden strenuous activities if you are not used to them. Stay hydrated, and if you experience dizziness or shortness of breath during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work and daily activities with regular monitoring.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as angioedema, severe hypotension, or kidney problems, seek immediate medical attention and follow your doctor's advice regarding discontinuation.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for controlling blood pressure. Regular monitoring of kidney function, potassium levels, and blood pressure is recommended. It may reduce the risk of cardiovascular events and kidney damage associated with hypertension. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and complement medicine.
Evidence: Well-establishedACE inhibitors, calcium channel blockers, diuretics, or beta-blockers may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known with this medicine. However, always inform your healthcare provider about all medicines you take before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same local time as much as possible, but consult your doctor for specific advice. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 2 to 4 weeks of regular use.
A: Yes, you can take this medicine with or without food. Taking it at the same time each day helps maintain consistent levels.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is not safe during pregnancy and can harm the baby. Inform your doctor immediately if you are pregnant or planning to become pregnant.
A: No, do not stop this medicine without consulting your doctor, as blood pressure may rise again.
🤔 Common Patient Concerns
🔄 Substitutes for azilura 40 tablet
View AllAlternative brands with exact same active ingredient:
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ibzil 40mg tabletIndiabulls pharmaceutical ltd ₹60.94 32.2% CHEAPER
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azilma 40 tabletRapross Pharmaceuticals Pvt Ltd ₹64.69 28% CHEAPER
-
Tenarbi 40 TabletOaknet Healthcare Pvt Ltd ₹64.69 28% CHEAPER
-
azipress 40mg tabletLividus Pharmaceuticals Pvt Ltd ₹65.63 26.9% CHEAPER
-
zarbil 40 tabletSinsan Pharmaceuticals ₹70.31 21.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Azilura 40 is a cure for high blood pressure.
Fact: It controls blood pressure but does not cure hypertension. Lifestyle changes and continued treatment are usually needed. - Myth: You can stop taking azilura 40 once your blood pressure is normal.
Fact: Blood pressure may rise again if you stop. Always consult your doctor before stopping. - Myth: Azilura 40 causes dry cough like ACE inhibitors.
Fact: Dry cough is much less common with this class of medicines compared to ACE inhibitors. - Myth: Azilura 40 is safe to take during pregnancy.
Fact: It is not safe during pregnancy and can harm the baby. Inform your doctor immediately if you become pregnant.
🔄 Alternative Options
Generic Alternatives
- Azilsartan medoxomil 40 mg tablet
Brand Alternatives
- Azilura 40 tablet