Azithral XP 150mg/1000mg/1000mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing
- Signs of liver toxicity: yellowing of skin or eyes, dark urine, severe fatigue
- Severe diarrhea with blood or mucus
- Irregular heartbeat, palpitations, or fainting
- Severe skin rash with blisters or peeling
- Persistent vomiting or inability to keep fluids down
If experiencing severe symptoms, call emergency services immediately.
What is azflo-kit used for?
This medicine is a combination of fluconazole (an antifungal) and azithromycin (an antibiotic) used to treat mixed infections. It works by killing fungi and stopping bacterial growth. It is available by prescription only.
- Generic Name: Fluconazole + Azithromycin
- Manufacturer: Biomax Biotechnics Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 azflo-kit के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुकोनाज़ोल और एज़िथ्रोमाइसिन का संयोजन है, जिसका उपयोग बैक्टीरियल और फंगल संक्रमणों के मिश्रित मामलों में किया जाता है। यह श्वसन तंत्र, त्वचा और जननांग संक्रमणों के इलाज में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, लीवर की समस्या, और दिल की धड़कन में गड़बड़ी हो सकती है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और न ही समय से पहले बंद करें। शराब से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को ठंडी और सूखी जगह पर रखें।
💊 azflo-kit Uses & Benefits
[{"condition":"Mixed respiratory tract infections","description":"Used when both bacterial and fungal pathogens are suspected, such as in patients with underlying lung disease or immunosuppression.","evidence":"Limited"},{"condition":"Complicated skin and soft tissue infections","description":"May be prescribed when fungal and bacterial co-infection is likely, especially in diabetic or immunocompromised patients.","evidence":"Limited"},{"condition":"Genital infections with mixed pathogens","description":"Sometimes used for persistent vaginal discharge where both Candida and bacterial pathogens are involved.","evidence":"Limited"}]
Off-label uses: [{"condition":"Prophylaxis in immunocompromised patients","description":"Occasionally used to prevent fungal and bacterial infections in high-risk patients, but not standard.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and fungal infections
Also treats: Respiratory tract infections, Skin infections, Genital infections
📋 Drug Information
| Generic Name(s) | Fluconazole + Azithromycin |
| Brand Name | Azithral XP 150mg/1000mg/1000mg Tablet |
| Manufacturer | Biomax Biotechnics Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Antifungal + Antibiotic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Fluconazole selectively inhibits fungal cytochrome P450-dependent 14-alpha-demethylase, blocking the conversion of lanosterol to ergosterol, a key component of the fungal cell membrane. This leads to increased membrane permeability and fungal cell death. Azithromycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting transpeptidation and translocation steps of protein synthesis, thereby stopping bacterial growth. Together, they provide antifungal and antibacterial action.
Mechanism Steps
💡 How to Take azflo-kit
Strength: Tablet containing fluconazole 150 mg and azithromycin 1000 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet containing fluconazole 150 mg and azithromycin 1000 mg taken orally once daily. However, the exact dose and duration depend on the type and severity of infection, your kidney and liver function, and other medications you take. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal function. Fluconazole is excreted by the kidneys, and renal function declines with age. Monitor closely for side effects. |
| Renal Impairment | Fluconazole dose should be reduced in patients with renal impairment. Azithromycin generally does not require adjustment, but use with caution. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Fluconazole and azithromycin can both affect the liver. Dose adjustment may be needed. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is one tablet (fluconazole 150 mg + azithromycin 1000 mg). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of azflo-kit
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Simvastatin | Major | |
| Amiodarone | Major | |
| Phenytoin | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Statins (e.g., simvastatin, atorvastatin)
- QT-prolonging drugs (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Phenytoin
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver toxicity from fluconazole and may worsen stomach upset and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to fluconazole, azithromycin, or other azoles/macrolides","Severe liver disease","History of cholestatic jaundice with azithromycin use","Concurrent use with QT-prolonging drugs","Pregnancy (especially high doses of fluconazole)"]
⚠️ Warnings & Precautions
["Do not use for viral infections.","Use with caution in patients with liver or kidney disease.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol.","Inform your doctor if you have heart rhythm problems.","Do not share this medicine with others.","Complete the full course as prescribed."]
🤱 Lactation Safety
Fluconazole and azithromycin are excreted in breast milk. Consult your doctor before breastfeeding while on this medicine. Your doctor may advise temporary discontinuation or alternative feeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, diarrhea, and liver toxicity. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may remove fluconazole but not azithromycin.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take the tablet with a full glass of water, with or without food. Avoid alcohol while taking this medicine, as it may increase the risk of liver problems and stomach upset. Inform your doctor if you have a history of liver disease, kidney disease, heart rhythm problems, or allergies to antibiotics. Do not share this medicine with others. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and are at higher risk of side effects. Dose adjustment may be needed. Monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Fluconazole may be harmful to the developing fetus, especially in high doses.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with antibiotics or painkillers used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue, avoid strenuous exercise until you know how the medicine affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest if you feel unwell.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use may increase risk of liver toxicity, fungal resistance, and bacterial resistance. Regular monitoring of liver and kidney function is advised if used for prolonged periods. Do not use for longer than prescribed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Instead of a fixed-dose combination, your doctor may prescribe individual drugs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1-2 days, but complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking with food reduces stomach upset.
A: Consult your doctor. Fluconazole may be harmful in high doses; azithromycin is generally considered safe.
🤔 Common Patient Concerns
🔄 Substitutes for azflo-kit
View AllAlternative brands with exact same active ingredient:
-
biskit capsuleChicky Pharma Pvt Ltd ₹41.12 53.8% CHEAPER
-
triokit combikitZest Pharma ₹42.19 52.6% CHEAPER
-
azithro 150 mg/1000 mg/1000 mg tabletWockhardt Ltd ₹42.56 52.2% CHEAPER
-
azax fs kitSun Pharmaceutical Industries Ltd ₹50.00 43.9% CHEAPER
-
hilfas kit 150mg/1000mg/2000mg tabletHindustan Latex Ltd ₹70.31 21.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any infection.
Fact: It only works for specific fungal and bacterial infections. It does not treat viral infections. - Myth: You can stop taking it once you feel better.
Fact: You must complete the full course to prevent recurrence and resistance.
🔄 Alternative Options
Generic Alternatives
- Fluconazole 150 mg + Azithromycin 1000 mg tablet (various manufacturers)
Brand Alternatives
- Azithral XP 150mg/1000mg/1000mg tablet