azerin 10 cream - Azelaic Acid (10% w/w) medicine

Aziderm 10% Cream: Complete Guide to Uses, Side Effects, and More

No reviews yet
🏭 Elixir Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for acne and rosacea; moderate for melasma and hyperpigmentation.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Severe skin blistering or peeling
  • Signs of infection (increased redness, warmth, pus)
  • Sudden worsening of skin condition
  • Severe burning or stinging that does not subside
  • Development of new or unusual skin lesions

If experiencing severe symptoms, call emergency services immediately.

What is azerin 10 cream used for?

Aziderm 10% Cream is a topical medication containing azelaic acid, used to treat acne, rosacea, and skin discoloration. It works by killing acne bacteria, reducing inflammation, and lightening dark spots. Apply a thin layer to the affected area twice daily, and always use sunscreen.

  • Generic Name: Azelaic Acid (10% w/w)
  • Manufacturer: Elixir Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 azerin 10 cream के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें एज़ेलाइक एसिड 10% w/w होता है। इसका उपयोग मुख्य रूप से मुँहासे (एक्ने) और रोसैसिया के इलाज के लिए किया जाता है। यह मुँहासे पैदा करने वाले बैक्टीरिया को कम करती है, सूजन को कम करती है, और त्वचा के दाग-धब्बों को हल्का करने में मदद करती है। यह त्वचा की बनावट को भी बेहतर बनाती है। इसका उपयोग बाहरी त्वचा पर ही किया जाता है। इसे डॉक्टर के निर्देशानुसार दिन में दो बार लगाएं। धूप में जाने से पहले सनस्क्रीन का उपयोग करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा, या सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी त्वचा का छिलना या पपड़ी बनना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर एलर्जी, सूजन, या छाले दिखें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल बाहरी त्वचा पर करें। आँखों, होंठों, और म्यूकस मेम्ब्रेन के संपर्क से बचें। टूटी या जली हुई त्वचा पर न लगाएं। धूप में जाने से पहले सनस्क्रीन लगाएं क्योंकि यह दवा त्वचा की धूप के प्रति संवेदनशीलता बढ़ा सकती है। अन्य कठोर त्वचा उत्पादों के साथ इसका उपयोग न करें। उपयोग से पहले और बाद में हाथ धोएं। बच्चों की पहुंच से दूर रखें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 azerin 10 cream Uses & Benefits

[{"condition":"Acne vulgaris","description":"Reduces the number of inflammatory and non-inflammatory acne lesions by inhibiting bacterial growth and unclogging pores.","evidence":"Well-established"},{"condition":"Rosacea","description":"Helps reduce redness, papules, and pustules associated with rosacea.","evidence":"Well-established"},{"condition":"Melasma","description":"May help lighten dark patches on the skin by reducing melanin production.","evidence":"Moderate"},{"condition":"Post-inflammatory hyperpigmentation","description":"Can help fade dark spots left after acne or other skin injuries.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Keratosis pilaris","description":"Sometimes used to improve the rough bumps on the skin.","evidence":"Limited"},{"condition":"Folliculitis","description":"May be used off-label to treat inflammation of hair follicles.","evidence":"Limited"}]

Primary treatment for: Acne vulgaris

Also treats: Rosacea, Melasma, Post-inflammatory hyperpigmentation

📋 Drug Information

Generic Name(s)Azelaic Acid (10% w/w)
Brand Nameazerin 10 cream
ManufacturerElixir Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntimicrobials- Acne
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer of this medicine to the affected area twice daily, or as directed by your doctor.
2
Cleanse your skin gently before applying the cream to enhance absorption.
3
Use a broad-spectrum sunscreen daily, as azelaic acid can make your skin more sensitive to the sun.
4
Avoid using other topical acne products unless your doctor approves, as they may increase irritation.
5
Be patient; it may take 4 to 8 weeks to see noticeable improvement.
6
If you experience severe irritation, reduce the frequency of application or consult your doctor.
7
Do not apply the cream to broken or irritated skin.
8
Keep the tube tightly closed and store at room temperature.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acne breakouts
This medicine is commonly prescribed for acne.
Likely Use
✅
Facial redness and bumps
This medicine is used for rosacea.
Likely Use
✅
Dark spots on skin
This medicine can help lighten hyperpigmentation.
Likely Use
❌
Fever
This medicine is not used for fever.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing topical application, azelaic acid is absorbed through the skin. The extent of absorption depends on the concentration, vehicle, and duration of application. Typically, less than 4% of the applied dose is absorbed systemically.
DistributionAfter absorption, azelaic acid distributes into the skin layers and to a lesser extent into the systemic circulation. It does not bind significantly to plasma proteins.
Protein BindingNot established from the available information.
MetabolismAzelaic acid is not significantly metabolized in the skin. Systemically absorbed azelaic acid is metabolized in the liver via beta-oxidation to shorter-chain dicarboxylic acids.
Half-LifeThe elimination half-life of azelaic acid is approximately 12 hours after topical application.
ExcretionAzelaic acid and its metabolites are primarily excreted unchanged in the urine.
BioavailabilityThe systemic bioavailability of topically applied azelaic acid is approximately 4% relative to an intravenous dose.
Onset of ActionImprovement in acne lesions may be noticed within 4 weeks, but full effects may take 8 to 12 weeks.
Peak Plasma TimePeak plasma concentrations are typically reached within 2 to 3 hours after topical application.
Duration of ActionThe effects of azelaic acid are cumulative and persist with continued use. The duration of action after a single application is not well defined.

How It Works

Azelaic acid exerts its effects through multiple mechanisms. It inhibits the enzyme tyrosinase, which is involved in melanin production, thereby reducing hyperpigmentation. It also has antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis by disrupting their cell wall synthesis and protein synthesis. Additionally, azelaic acid normalizes keratinization, helping to prevent clogged pores. It possesses anti-inflammatory properties by reducing the production of reactive oxygen species and inhibiting the release of pro-inflammatory cytokines.

Mechanism Steps

1
Inhibition of tyrosinase: Azelaic acid competitively inhibits tyrosinase, an enzyme crucial for melanin production, thereby reducing hyperpigmentation.
2
Antibacterial action: It disrupts the cell wall and protein synthesis of acne-causing bacteria, reducing their population on the skin.
3
Anti-inflammatory effect: Azelaic acid scavenges free radicals and inhibits pro-inflammatory cytokines, decreasing redness and swelling.
4
Normalization of keratinization: It helps regulate the turnover of skin cells, preventing the formation of comedones.

💡 How to Take azerin 10 cream

Strength: Cream containing azelaic acid 10% w/w.

1Wash your hands and the affected area with a mild cleanser and water.
2Pat the skin dry gently.
3Apply a thin layer of the cream to the affected area, avoiding the eyes, lips, and mucous membranes.
4Rub it in gently until it is absorbed.
5Wash your hands after application.
6Use twice daily or as directed by your doctor.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area twice daily (morning and evening) after cleansing the skin. The dose and frequency may be adjusted by your doctor based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. Use as directed by a doctor.
Renal ImpairmentNo dosage adjustment is required for patients with renal impairment due to minimal systemic absorption.
Hepatic ImpairmentNo dosage adjustment is required for patients with hepatic impairment due to minimal systemic absorption.
Maximum Daily DoseNot established from the available information. Use as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Not applicable
No food restrictions
This is a topical medicine and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of azerin 10 cream

✅ Common Side Effects

Application site burning (Common (5-10%))
Usually resolves with continued use. If severe, reduce frequency or consult doctor.
Application site stinging (Common (5-10%))
Apply a moisturizer before or after to reduce stinging. Consult doctor if persistent.
Application site itching (Common (5-10%))
Avoid scratching. Consult doctor if itching is severe or accompanied by rash.
Erythema (redness) (Common (5-10%))
Usually temporary. If redness worsens, stop use and consult doctor.
Dryness of skin (Common (5-10%))
Use a gentle moisturizer. Consult doctor if dryness is severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, or difficulty breathing.
Severe skin irritation (Rare (<0.1%))
Stop using the medicine and consult a doctor if you develop severe blistering, peeling, or swelling.

⚠️ Rare Side Effects

Hypopigmentation
Consult a doctor if you notice lightening of the skin beyond the treated area.
Contact dermatitis
Discontinue use and consult a doctor if you develop a rash or eczema at the application site.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Benzoyl peroxide Moderate
Tretinoin Moderate
Salicylic acid Moderate
Alcohol-containing skincare Minor

⚡ Moderate Interactions

  • Other topical acne treatments (e.g., benzoyl peroxide, tretinoin, salicylic acid)

🍷 Alcohol Interaction

No known interaction between alcohol and topically applied azelaic acid. However, alcohol consumption may worsen skin conditions like rosacea, so moderation is advised.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to azelaic acid or any component of the formulation"]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, lips, and mucous membranes.","Do not apply to broken or irritated skin.","Use sunscreen daily as azelaic acid may increase sun sensitivity.","Avoid concurrent use of other topical irritants.","Consult a doctor if symptoms persist or worsen after 4-6 weeks of use.","Keep out of reach of children.","If you are pregnant or breastfeeding, consult your doctor before use."]

🤱 Lactation Safety

Azelaic acid is generally considered safe during breastfeeding. It is not known whether it passes into breast milk in significant amounts. Apply to the skin and avoid applying to the breast area to prevent infant exposure. Consult your doctor for advice.

💊 Overdose Management

Overdose with topical azelaic acid is unlikely due to limited systemic absorption. If excessive amounts are applied, rinse the area thoroughly with water. If ingested, seek medical attention immediately.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, lips, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or irritated skin. Use sunscreen daily, as this medicine may increase sensitivity to sunlight. Avoid using other topical products that may irritate the skin, such as harsh cleansers or exfoliants, unless advised by your doctor. Wash your hands before and after applying the cream. Do not cover the treated area with tight dressings or bandages unless instructed. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for a condition for which it was not prescribed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

No specific precautions are required for elderly patients. Use as directed by your doctor.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Azelaic acid is considered safe during pregnancy, but your doctor may adjust your treatment plan.

🏥 Post-Surgery Considerations

If you are undergoing surgery, inform your surgeon that you are using this medicine. It is generally safe to continue, but your surgeon may advise temporary discontinuation based on the procedure.

🦷 Dental Procedures

No specific precautions for dental procedures. Continue using this medicine as usual.

💚 Lifestyle Tips for Better Results

🏃
Maintain a consistent skincare routine with gentle cleansers and moisturizers.
🥗
Avoid picking or squeezing acne lesions to prevent scarring.
😴
Use non-comedogenic makeup and skincare products.
💧
Manage stress through relaxation techniques, as stress can worsen acne.
🧘
Get adequate sleep to support skin health.
🌞
Stay hydrated by drinking plenty of water.

🏋️ Exercise Considerations

No specific exercise restrictions while using this medicine. However, if you exercise outdoors, apply sunscreen before going out, as azelaic acid can increase sun sensitivity. Shower and cleanse your skin after sweating to prevent pore clogging.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit high-glycemic foods that may worsen acne.
Include omega-3 fatty acids from fish or flaxseed.
Stay hydrated by drinking plenty of water.

💼 Impact on Daily Work & Life

This medicine has no impact on your ability to drive or operate machinery. It is applied topically and does not cause drowsiness. You can continue your daily activities as usual.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor immediately. Your doctor will advise you on whether to continue or stop treatment.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe. It does not cause thinning of the skin or other serious side effects associated with some other acne treatments. However, regular follow-up with your doctor is recommended to monitor your skin's response and adjust treatment as needed. If you use it for extended periods, your doctor may periodically reassess your condition.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Salicylic acid cleansers

Can help unclog pores and treat mild acne.

Evidence: Well-established
Tea tree oil

Has antibacterial properties and may help with mild acne.

Evidence: Moderate
Phototherapy

Light therapy can reduce acne-causing bacteria and inflammation.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and heat. If you are traveling across time zones, continue applying it as per your usual schedule; no time zone adjustment is needed for topical medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 24-year-old woman with mild to moderate acne
She started using this medicine as prescribed by her dermatologist. After 6 weeks of consistent use, she noticed a significant reduction in her acne breakouts and fading of old acne marks. She experienced mild dryness initially, which was managed with a moisturizer.
💡 Lesson: Consistent use and proper skin care can lead to good results with this medicine.
👤 A 45-year-old man with rosacea
He was prescribed this medicine for rosacea. He applied it twice daily and used sunscreen regularly. After 8 weeks, his facial redness and bumps were noticeably reduced. He did not experience any serious side effects.
💡 Lesson: This medicine can be effective for rosacea when used as directed and with sun protection.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start seeing improvement in 4 weeks, but full effects may take 8 to 12 weeks of consistent use.

Q: Can I use it with other acne treatments?

A: Consult your doctor before combining with other acne treatments, as it may increase skin irritation.

Q: Is it safe during pregnancy?

A: Azelaic acid is considered safe during pregnancy (Category B), but consult your doctor before use.

Q: What should I do if I miss a dose?

A: Apply it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it make my skin dry?
  • Can I use makeup over this medicine?
  • Does it interact with my other skincare products?
  • What if I miss a dose?
  • Can I use it during pregnancy?

🔄 Substitutes for azerin 10 cream

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Aziderm 10% Cream works overnight.
    Fact: It may take several weeks to see noticeable improvement. Consistent use is key.
  • Myth: You can stop using it once acne clears.
    Fact: Stopping too soon may cause acne to return. Follow your doctor's advice on duration.
  • Myth: More cream means faster results.
    Fact: Applying more than a thin layer can increase irritation without improving efficacy.

🔄 Alternative Options

Generic Alternatives

  • Azelaic acid 10% cream (various manufacturers)

Brand Alternatives

  • Aziderm 10% Cream

📊 Comparison with Similar Medicines

[{"medicine":"Azelaic acid 10% cream","class":"Dicarboxylic acid","primary_use":"Acne, rosacea","route":"Topical","common_side_effects":"Mild irritation, dryness"},{"medicine":"Benzoyl peroxide 5% cream","class":"Antibacterial","primary_use":"Acne","route":"Topical","common_side_effects":"Dryness, peeling, redness"},{"medicine":"Tretinoin 0.05% cream","class":"Retinoid","primary_use":"Acne, photoaging","route":"Topical","common_side_effects":"Peeling, redness, sun sensitivity"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory