Aziderm 10% Gel: Comprehensive Guide to Uses, Side Effects, and More
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (rash, hives, swelling of face, lips, or throat, difficulty breathing)
- Severe skin irritation, blistering, or peeling
- Signs of infection (increased redness, warmth, pus)
- Worsening of acne despite consistent use
- No improvement after 12 weeks of treatment
If experiencing severe symptoms, call emergency services immediately.
What is dermac 10% cream used for?
This medicine is a topical gel containing 10% azelaic acid used to treat acne and rosacea. It works by killing acne bacteria, reducing inflammation, and unclogging pores. Apply a thin layer twice daily to clean, dry skin.
- Generic Name: Azelaic Acid
- Manufacturer: Gary Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dermac 10% cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल जेल है जिसमें 10% एज़ेलाइक एसिड होता है। इसका उपयोग मुँहासे (एक्ने) और रोसेशिया के इलाज के लिए किया जाता है। यह मुँहासे पैदा करने वाले बैक्टीरिया को मारती है, सूजन कम करती है, और बंद रोमछिद्रों को खोलती है। यह त्वचा पर लगाने वाली दवा है और इसे दिन में दो बार साफ त्वचा पर लगाया जाता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूखापन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर एलर्जी, सूजन, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी एलर्जी और अन्य दवाओं के बारे में बताएं। आँखों, मुँह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। धूप में बाहर जाते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। अन्य त्वचा उत्पादों का उपयोग सावधानी से करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 dermac 10% cream Uses & Benefits
[{"condition":"Acne vulgaris","description":"This medicine is used to treat mild to moderate inflammatory and non-inflammatory acne lesions.","evidence":"Well-established"},{"condition":"Post-inflammatory hyperpigmentation","description":"This medicine may help lighten dark spots left after acne lesions heal.","evidence":"Moderate"},{"condition":"Rosacea","description":"This medicine can reduce redness and bumps associated with rosacea.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Melasma","description":"Sometimes used off-label to lighten dark patches on the skin.","evidence":"Limited"}]
Primary treatment for: Acne vulgaris
Also treats: Rosacea, Post-inflammatory hyperpigmentation
📋 Drug Information
| Generic Name(s) | Azelaic Acid |
| Brand Name | Aziderm 20% Cream |
| Manufacturer | Gary Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antimicrobials- Acne |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Keep away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through multiple mechanisms. Azelaic acid inhibits the synthesis of proteins in Propionibacterium acnes, reducing its population on the skin. It also normalizes keratinization by decreasing the production of keratin, which helps prevent the formation of comedones. Additionally, it has anti-inflammatory effects by reducing the production of reactive oxygen species and inhibiting the release of pro-inflammatory cytokines. This medicine also inhibits tyrosinase, an enzyme involved in melanin production, which helps reduce hyperpigmentation.
Mechanism Steps
💡 How to Take dermac 10% cream
Strength: Gel containing 10% w/w azelaic acid.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area twice daily (morning and evening) after cleansing the skin. The dose and frequency may be adjusted by your doctor based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are required for elderly patients. However, consult a doctor for personalized advice. |
| Renal Impairment | No dosage adjustment is required for renal impairment as systemic absorption is minimal. |
| Hepatic Impairment | No dosage adjustment is required for hepatic impairment as systemic absorption is minimal. |
| Maximum Daily Dose | Not established from the available information. Use as directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dermac 10% cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Retinoids (topical) | Moderate | |
| Benzoyl peroxide (topical) | Moderate | |
| Alcohol-containing skincare products | Minor |
⚡ Moderate Interactions
- Other topical acne treatments (e.g., retinoids, benzoyl peroxide)
🍷 Alcohol Interaction
No known interaction between this medicine and alcohol when used topically. However, alcohol consumption may worsen acne in some individuals.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to azelaic acid or any component of the gel"]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes, lips, and mucous membranes.","Do not apply to broken or irritated skin.","Use sunscreen and protective clothing during treatment.","Avoid concurrent use of other topical irritants.","Consult a doctor if no improvement after 12 weeks of use."]
🤱 Lactation Safety
It is not known whether azelaic acid passes into breast milk. Consult your doctor before using this medicine while breastfeeding. Avoid applying to the breast area to prevent infant exposure.
💊 Overdose Management
Overdose with topical azelaic acid is unlikely. If excessive amounts are applied, rinse the area with water and consult a doctor if irritation occurs.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Before using this medicine, inform your doctor if you are allergic to azelaic acid or any other medications. Avoid contact with the eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to open wounds or areas of sunburn. Use sunscreen and protective clothing when outdoors, as this medicine may increase sensitivity to sunlight. Avoid using other topical products that may irritate the skin, such as harsh cleansers, alcohol-based products, or abrasive scrubs, unless advised by your doctor. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Do not use this medicine for any condition other than that for which it was prescribed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
No specific precautions for elderly patients. However, consult a doctor for personalized advice.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It is generally considered safe, but medical guidance is recommended.
🏥 Post-Surgery Considerations
Avoid applying this medicine to surgical wounds or areas of broken skin. Consult your doctor before resuming use after surgery.
🦷 Dental Procedures
No specific considerations for dental procedures. Continue use as normal unless advised otherwise by your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions. However, if you sweat heavily, gently cleanse your skin afterward to prevent pore clogging.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine does not affect your ability to drive or operate machinery. It can be applied before work or school as part of your daily routine.
🛑 When to Stop This Medicine
Do not stop using this medicine without consulting your doctor. If you experience severe side effects or no improvement after 12 weeks, consult your doctor for alternative treatments.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe. It does not cause thinning of the skin or other serious side effects associated with some acne treatments. Regular monitoring by a dermatologist is recommended to assess effectiveness and adjust treatment as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help unclog pores and reduce mild acne.
Evidence: Well-establishedHas antibacterial properties and may reduce acne.
Evidence: ModerateLight therapy can reduce acne-causing bacteria.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. Continue routine vaccinations as scheduled.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store at room temperature and avoid extreme heat or cold. If crossing time zones, continue your regular application schedule as closely as possible. Keep the gel in your carry-on luggage if flying, as checked baggage may expose it to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start seeing improvement in 4 weeks, but it can take up to 12 weeks for full effects.
A: Consult your doctor before combining with other topical treatments, as it may increase irritation.
A: It is generally well-tolerated, but if you have sensitive skin, start with once-daily application and use a moisturizer.
A: Consult your doctor before use. It is often considered safe, but medical advice is necessary.
🤔 Common Patient Concerns
🔄 Substitutes for dermac 10% cream
View AllAlternative brands with exact same active ingredient:
-
azecne creamMedley Pharmaceuticals ₹65.63 48.1% CHEAPER
-
Aze CreamWest-Coast Pharmaceutical Works Ltd ₹96.48 23.8% CHEAPER
-
azac 10% creamMark India ₹121.88 3.7% CHEAPER
-
az acnewin 10% creamAmwill Healthcare ₹150.00 18.5% COSTLIER
-
acnerus az 10% gelCyrus Remedies ₹159.38 25.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Azelaic acid makes skin sensitive to the sun.
Fact: Azelaic acid does not significantly increase sun sensitivity, but using sunscreen is still recommended. - Myth: Azelaic acid works overnight.
Fact: It may take several weeks to see noticeable improvement.
🔄 Alternative Options
Generic Alternatives
- Azelaic acid 10% gel (various manufacturers)
Brand Alternatives
- Aziderm 10% Gel
- Azelaic Acid 10% Gel