Aldigesic P 50mg/125mg Oral Suspension: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is azeclo oral suspension used for?
This medicine is a combination of aceclofenac and paracetamol used for short-term relief of pain and fever. It works by reducing inflammation and pain. Take it with food and avoid alcohol.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Ozenius Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 azeclo oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग दर्द और बुखार से राहत के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द और ऑस्टियोआर्थराइटिस में प्रभावी है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। शराब का सेवन न करें। अन्य दर्द निवारक दवाओं के साथ लेने से पहले डॉक्टर से सलाह लें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से परामर्श करें।
💊 azeclo oral suspension Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgery.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever associated with various conditions.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"May be used for short-term relief of pain and stiffness in osteoarthritis.","evidence":"Established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but other NSAIDs are preferred.","evidence":"Limited"}]
Primary treatment for: Acute pain and fever
Also treats: Musculoskeletal pain, Dental pain, Post-operative pain, Osteoarthritis
📋 Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
| Brand Name | Aldigesic P |
| Manufacturer | Ozenius Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a nonsteroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis and may also modulate pain perception through other pathways. Together, they provide effective analgesia and antipyresis.
Mechanism Steps
💡 How to Take azeclo oral suspension
Strength: Each 5 ml of oral suspension contains Aceclofenac 50 mg and Paracetamol 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 ml (providing 50 mg aceclofenac and 125 mg paracetamol) taken orally two to three times daily, or as directed by your doctor. The dose may be adjusted based on the severity of pain and the patient's response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed 30 ml (150 mg aceclofenac and 375 mg paracetamol) in divided doses, unless otherwise prescribed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of azeclo oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Antihypertensives | Moderate | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- Corticosteroids
- Methotrexate
⚡ Moderate Interactions
- Antihypertensives
- Diuretics
- Lithium
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and liver damage, especially with paracetamol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to aceclofenac, paracetamol, or any component of the formulation","Active peptic ulcer or history of recurrent ulcers","Severe renal impairment","Severe hepatic impairment","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Third trimester of pregnancy","Children under 12 years (unless specifically prescribed)"]
⚠️ Warnings & Precautions
["Take with food to reduce gastrointestinal irritation.","Avoid alcohol during treatment.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients and those with kidney or liver disease.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for more than 7 days without medical advice.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","May interact with other medications; inform your doctor about all medicines you are taking."]
🤱 Lactation Safety
Aceclofenac and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding. Paracetamol is generally considered safe, but aceclofenac should be used with caution.
💊 Overdose Management
Overdose can cause severe liver damage, especially from paracetamol. Symptoms of overdose may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver damage. Do not take other pain relievers or fever reducers containing paracetamol or NSAIDs without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and at the lowest effective dose for the shortest duration.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning pregnancy. NSAIDs may affect ovulation and are not recommended during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but consult your surgeon before use, especially if you are on blood thinners or have kidney problems.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine, especially if you have pain or inflammation. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take with food.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if symptoms persist beyond 7 days, if you experience severe side effects, or if you develop signs of gastrointestinal bleeding, liver problems, or allergic reactions.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, and liver damage. Regular monitoring of liver and kidney function is advised. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help reduce pain and inflammation.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep a sufficient supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking this medicine.
A: It is best taken with food or milk to reduce stomach upset.
A: Pediatric dosing is not established. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for azeclo oral suspension
View AllAlternative brands with exact same active ingredient:
-
movexx plus syrupCipla Ltd ₹14.22 66.9% CHEAPER
-
acezof-plus oral suspensionBioshine Healthcare Pvt Ltd ₹27.00 37.2% CHEAPER
-
aloo 50mg/5ml/125mg/5ml syrupBestoChem Formulations India Ltd ₹29.00 32.6% CHEAPER
-
afib p 50mg/125mg oral suspensionSamco Pharma Works Pvt Ltd ₹35.00 18.6% CHEAPER
-
vriace p oral suspensionGopal Lifesciences ₹36.00 16.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: It is intended for short-term use only. Long-term use requires medical supervision. - Myth: It is safe to take with alcohol.
Fact: Alcohol increases the risk of liver damage and stomach bleeding. - Myth: More medicine means faster relief.
Fact: Exceeding the dose can cause serious harm. Always follow the prescribed dose.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac + Paracetamol oral suspension (generic)
Brand Alternatives
- Aldigesic P 50mg/125mg Oral Suspension