axocare tablet - Methylcobalamin (750mcg) + Pregabalin (75mg) medicine

Axocare Tablet - Uses, Price, Side Effects, and More

4.5 (14 reviews)
๐Ÿญ Olamic Pharma Pvt. Ltd. ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is axocare tablet used for?

Axocare Tablet is a combination of Methylcobalamin (750mcg) and Pregabalin (75mg) used to treat neuropathic pain and nerve damage. Methylcobalamin helps repair nerve cells, while Pregabalin reduces pain signals in the brain. It is prescribed for conditions like diabetic neuropathy and postherpetic neuralgia.

  • Generic Name: Methylcobalamin + Pregabalin
  • Manufacturer: Olamic Pharma Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š axocare tablet Uses & Benefits

Diabetic neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury.

Off-label uses: Generalized anxiety disorder, social anxiety disorder, restless legs syndrome.

๐Ÿ“‹ Drug Information

Generic Name(s)Methylcobalamin + Pregabalin
Brand NameAxogurd-SR Tablet
ManufacturerOlamic Pharma Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassNeurotropic vitamin + Gabapentinoid
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMethylcobalamin: Well absorbed orally; Pregabalin: Rapidly absorbed after oral administration with peak plasma concentrations within 1 hour.
DistributionMethylcobalamin: Distributed to tissues including CNS; Pregabalin: Crosses blood-brain barrier, distributed throughout body.
Protein BindingMethylcobalamin: Low (<10%); Pregabalin: <1% bound to plasma proteins.
MetabolismMethylcobalamin: Metabolized in the liver; Pregabalin: Negligible metabolism (<2% of dose).
Half-LifeMethylcobalamin: Approximately 6 hours; Pregabalin: Approximately 6.3 hours.
ExcretionMethylcobalamin: Renal excretion; Pregabalin: Primarily excreted unchanged in urine (90-99%).
BioavailabilityMethylcobalamin: Variable, approximately 50%; Pregabalin: >90%.
Onset of ActionMethylcobalamin: Days to weeks; Pregabalin: Within 1 hour.
Peak Plasma TimeMethylcobalamin: 2-3 hours; Pregabalin: 1 hour.
Duration of ActionMethylcobalamin: Several hours; Pregabalin: 6-8 hours.

How It Works

Methylcobalamin: Coenzyme for myelin synthesis; Pregabalin: Binds to alpha2-delta subunit of voltage-gated calcium channels, reducing calcium influx and neurotransmitter release.

Mechanism Steps

1Methylcobalamin acts as a cofactor for methionine synthase, promoting myelin synthesis.
2Pregabalin binds to the alpha2-delta subunit of voltage-gated calcium channels in the CNS.
3Binding reduces calcium influx at nerve terminals.

๐Ÿ’ก How to Take axocare tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of axocare tablet

โœ… Common Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Constipation

๐Ÿšจ Serious Side Effects

  • Angioedema
  • Hypersensitivity reactions
  • Suicidal thoughts
  • Rhabdomyolysis
  • PR interval prolongation

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Hepatotoxicity
  • Pancreatitis
  • Blood dyscrasias

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Moderate Increased dizziness and drowsiness
Opioid painkillers Major Enhanced CNS depression, respiratory depression risk
Oral hypoglycemics Moderate May alter blood sugar levels

๐Ÿšจ Major Interactions

  • Central nervous system depressants
  • Thalidomide
  • Angiotensin-converting enzyme inhibitors

โšก Moderate Interactions

  • Oral hypoglycemics
  • Antihypertensives

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 blockers

๐Ÿฝ๏ธ Food Interactions

High-fat meal may delay absorption of pregabalin

๐Ÿท Alcohol Interaction

Additive CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component; severe renal impairment (CrCl <30 mL/min) for pregabalin.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, CBC, signs of hypersensitivity, CNS depression, suicidal ideation.

๐Ÿคฑ Lactation Safety

Pregabalin excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; hemodialysis may remove pregabalin.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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