Axein 500mg Tablet - Uses, Price, Side Effects
What is axein 500mg tablet used for?
Axein 500mg Tablet contains Cefuroxime, a cephalosporin antibiotic used to treat bacterial infections like respiratory tract infections, urinary tract infections, skin infections, and ear infections. It works by stopping the growth of bacteria. Take it as prescribed, usually twice daily with or without food.
- Generic Name: Cefuroxime
- Manufacturer: Shakam Lifesciences
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ axein 500mg tablet Uses & Benefits
Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, gonorrhea, Lyme disease.
Off-label uses: Prophylaxis for surgical infections, treatment of bone and joint infections.
๐ Drug Information
| Generic Name(s) | Cefuroxime |
| Brand Name | Altacef 500 Tablet |
| Manufacturer | Shakam Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase and autolysin activity.
Mechanism Steps
๐ก How to Take axein 500mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of axein 500mg tablet
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions (if IV)
๐จ Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Clostridioides difficile diarrhea
- Seizures (high doses)
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Interstitial nephritis
- Hepatitis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Probenecid | Moderate | Increased cefuroxime levels |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
๐จ Major Interactions
- Warfarin
- Probenecid
- Live typhoid vaccine
- BCG vaccine
โก Moderate Interactions
- Loop diuretics
- Aminoglycosides
- Oral contraceptives
- BCG (intravesical)
โน๏ธ Minor Interactions
- Antacids
- H2 antagonists
- Proton pump inhibitors
๐ฝ๏ธ Food Interactions
Food increases absorption; take with food.
๐ท Alcohol Interaction
No known interaction; but may increase risk of disulfiram-like reaction (rare).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cefuroxime or other cephalosporins; previous immediate hypersensitivity reaction to penicillins.
๐ Monitoring Parameters
Renal function, signs of hypersensitivity, superinfection, bleeding (if on warfarin).
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for axein 500mg tablet
View AllAlternative brands with exact same active ingredient (Cefuroxime (500mg)):
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cefaxil 500mg tabletLark Laboratories Ltd โน1.17 99.8% CHEAPER
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voxcef 500mg tabletExmed Health Care โน55.00 88.4% CHEAPER
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cefactin 500mg tabletGlenmark Pharmaceuticals Ltd โน57.42 87.9% CHEAPER
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cefpil 500mg tabletPsychotropics India Ltd โน64.45 86.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.