avgesic p syrup
What is avgesic p syrup used for?
Aldigesic P (Aceclofenac + Paracetamol) is used to treat PAIN ANALGESICS. It contains Aceclofenac (50mg/5ml) + Paracetamol (125mg/5ml), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Accuminn Labs
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ avgesic p syrup Uses & Benefits
Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.
Off-label uses: Postoperative pain, migraine (limited evidence).
๐ Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
| Brand Name | Aldigesic P |
| Manufacturer | Accuminn Labs |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Mechanism Steps
๐ก How to Take avgesic p syrup
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of avgesic p syrup
โ Common Side Effects
- Nausea
- Dizziness
- Drowsiness
- Rash
- GI upset
๐จ Serious Side Effects
- GI bleeding
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased risk of GI ulceration |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic efficacy |
| Anticoagulants | Moderate | Increased INR |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of aceclofenac |
| Cholestyramine | Minor | Reduced absorption of paracetamol |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid alcohol.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.
๐ Monitoring Parameters
Liver function tests, renal function, CBC, blood pressure.
๐คฑ Lactation Safety
Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.