auto relief eye drop - Ofloxacin (0.3% w/v) + Dexamethasone (0.1% w/v) medicine

auto relief eye drop - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ P R G Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is auto relief eye drop used for?

Auto Relief Eye Drop (Ofloxacin + Dexamethasone) is used to treat OPHTHAL. It contains Ofloxacin (0.3% w/v) + Dexamethasone (0.1% w/v), which Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA rep. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ofloxacin + Dexamethasone
  • Manufacturer: P R G Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š auto relief eye drop Uses & Benefits

Treatment of bacterial conjunctivitis and blepharitis with inflammation; postoperative ocular inflammation

Off-label uses: Uveitis; scleritis; dry eye with inflammation

๐Ÿ“‹ Drug Information

Generic Name(s)Ofloxacin + Dexamethasone
Brand NameAuto Relief Eye Drop
ManufacturerP R G Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassAntibiotic + Corticosteroid
Route of AdministrationOphthalmic (topical)
StorageStore at 15-30ยฐC; protect from light; keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after ophthalmic administration
DistributionDistributes into ocular tissues; minimal systemic distribution
Protein BindingOfloxacin: ~20%; Dexamethasone: ~70%
MetabolismOfloxacin: Hepatic; Dexamethasone: Hepatic
Half-LifeOfloxacin: 4-5 hours; Dexamethasone: 3-4 hours
ExcretionOfloxacin: Renal; Dexamethasone: Renal
BioavailabilityLow systemic bioavailability due to topical administration
Onset of ActionRapid (within minutes to hours)
Peak Plasma TimeNot applicable (topical); systemic peak minimal
Duration of ActionSeveral hours

How It Works

Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Dexamethasone suppresses inflammation by inhibiting phospholipase A2, reducing prostaglandin and leukotriene synthesis.

Mechanism Steps

1Ofloxacin enters bacterial cells and binds to DNA gyrase and topoisomerase IV, inhibiting DNA replication and transcription.
2Dexamethasone binds to glucocorticoid receptors in target cells, leading to inhibition of phospholipase A2 and reduced production of prostaglandins and leukotrienes.
3Combined effect results in reduced bacterial growth and inflammation.

๐Ÿ’ก How to Take auto relief eye drop

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of auto relief eye drop

โœ… Common Side Effects

  • Eye irritation
  • Stinging
  • Blurred vision
  • Tearing

๐Ÿšจ Serious Side Effects

  • Increased intraocular pressure
  • Cataract formation
  • Secondary infection
  • Corneal perforation

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Periorbital edema
  • Dermatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
NSAIDs Major Increased risk of gastrointestinal bleeding
Anticoagulants Major Enhanced anticoagulant effect
Corticosteroids (systemic) Moderate Additive immunosuppression
Antidiabetic agents Moderate May alter blood glucose levels
CYP3A4 inducers/inhibitors Moderate Altered dexamethasone metabolism
Antacids Minor Reduced absorption of ofloxacin
Iron supplements Minor Reduced absorption of ofloxacin
Zinc supplements Minor Reduced absorption of ofloxacin

๐Ÿšจ Major Interactions

  • Warfarin
  • NSAIDs
  • Anticoagulants

โšก Moderate Interactions

  • Corticosteroids (systemic)
  • Antidiabetic agents
  • CYP3A4 inducers/inhibitors

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements
  • Zinc supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ofloxacin, dexamethasone, or any component; viral infections of the cornea (e.g., herpes simplex); fungal infections; untreated bacterial infections

๐Ÿ“Š Monitoring Parameters

Intraocular pressure (if prolonged use); signs of secondary infection; corneal healing

๐Ÿคฑ Lactation Safety

Caution; limited data; use only if clearly needed

๐Ÿ’Š Overdose Management

Flush eye with water; symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install