auto relief eye drop - Ofloxacin (0.3% w/v) + Dexamethasone (0.1% w/v) medicine

Auto Relief Eye Drop: Complete Guide to Uses, Side Effects, and Safety

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🏭 P R G Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or sudden vision loss
  • Swelling of the face, lips, or throat
  • Signs of allergic reaction such as rash, itching, or difficulty breathing
  • Increased redness, discharge, or swelling that worsens despite treatment
  • Eye pain or blurred vision that persists or worsens
  • New onset of flashes, floaters, or curtain-like vision loss

If experiencing severe symptoms, call emergency services immediately.

What is auto relief eye drop used for?

This medicine is a combination eye drop containing ofloxacin (an antibiotic) and dexamethasone (a steroid). It is used to treat bacterial eye infections that are accompanied by inflammation. It works by killing bacteria and reducing swelling, redness, and itching in the eye.

  • Generic Name: Ofloxacin + Dexamethasone
  • Manufacturer: P R G Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 auto relief eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा एक संयोजन नेत्र बूंद है जिसमें ऑफ़लोक्सासिन (एक एंटीबायोटिक) और डेक्सामेथासोन (एक स्टेरॉयड) शामिल हैं। इसका उपयोग बैक्टीरियल आंखों के संक्रमण के इलाज के लिए किया जाता है जिसमें सूजन भी होती है। यह बैक्टीरिया को मारकर और आंखों की सूजन, लालिमा और खुजली को कम करके काम करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में आंखों में जलन, अस्थायी धुंधली दृष्टि, और आंखों में कुछ महसूस होना शामिल है। गंभीर दुष्प्रभावों में एलर्जी प्रतिक्रिया, आंखों में दर्द, या दृष्टि में बदलाव हो सकते हैं। यदि आपको गंभीर लक्षण दिखाई दें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को अपनी एलर्जी और चिकित्सीय स्थिति के बारे में बताएं। कॉन्टैक्ट लेंस पहनने से पहले उन्हें निकाल लें और दवा डालने के 15 मिनट बाद ही वापस पहनें। दवा की ड्रॉपर टिप को आंखों या किसी सतह को न छुएं। निर्धारित अवधि से अधिक इसका उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 auto relief eye drop Uses & Benefits

[{"condition":"Bacterial conjunctivitis","description":"Treats bacterial infection of the conjunctiva, reducing redness, discharge, and irritation.","evidence":"Well-established"},{"condition":"Blepharitis","description":"Helps control bacterial infection and inflammation of the eyelids.","evidence":"Well-established"},{"condition":"Keratitis","description":"Used for bacterial corneal ulcers and inflammation, under close ophthalmologic supervision.","evidence":"Well-established"},{"condition":"Post-operative ocular inflammation","description":"Prevents and treats inflammation after cataract or other eye surgeries when bacterial infection is a concern.","evidence":"Well-established"},{"condition":"Traumatic eye injury with infection risk","description":"Reduces inflammation and prevents bacterial infection after minor ocular trauma.","evidence":"Limited"}]

Off-label uses: [{"condition":"Allergic conjunctivitis with suspected secondary bacterial infection","description":"Sometimes prescribed when both allergic inflammation and bacterial infection are suspected.","evidence":"Limited"},{"condition":"Dry eye with inflammation","description":"Rarely used short-term to reduce severe inflammation in dry eye syndrome, but not routinely recommended.","evidence":"Limited"}]

Primary treatment for: Bacterial eye infections with inflammation

Also treats: Bacterial conjunctivitis, Blepharitis, Keratitis, Post-operative ocular inflammation

📋 Drug Information

Generic Name(s)Ofloxacin + Dexamethasone
Brand NameAuto Relief Eye Drop
ManufacturerP R G Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassAntibiotic + Corticosteroid
Route of AdministrationOphthalmic (topical ocular)
StorageStore at room temperature (15-30°C). Protect from light and freezing. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture, or as indicated on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this medicine to prevent contamination.
2
Do not touch the dropper tip to your eye, eyelid, or any surface, as this can introduce bacteria into the bottle.
3
If you are using other eye drops, wait at least 5-10 minutes between applications to avoid washing out the medicine.
4
Do not use this medicine for longer than prescribed, as prolonged use can increase the risk of side effects such as increased eye pressure and cataracts.
5
If your symptoms do not improve within 2-3 days or worsen, contact your ophthalmologist immediately.
6
Remove contact lenses before using this medicine and wait at least 15 minutes before reinserting them.
7
Keep the bottle tightly closed when not in use and store it at room temperature.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Red eye with discharge
This medicine is commonly prescribed for bacterial conjunctivitis.
Likely Use
✅
Eye pain and swelling
It helps reduce inflammation and infection.
Likely Use
❌
Dry eye
This medicine is not a primary treatment for dry eye.
Not Primary
❌
Allergic eye itching without infection
Not recommended unless there is a bacterial infection.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOfloxacin and dexamethasone are absorbed systemically to a limited extent after topical ocular administration. Systemic absorption is generally low but can occur, especially if the eye is inflamed or if the drops are used frequently.
DistributionAfter ocular administration, both drugs distribute into the aqueous humor and other ocular tissues. Dexamethasone is highly protein-bound and distributes into various body tissues. Ofloxacin distributes widely into body fluids and tissues.
Protein BindingOfloxacin is approximately 20-30% protein-bound. Dexamethasone is about 77% protein-bound, primarily to albumin.
MetabolismOfloxacin is minimally metabolized in the liver, with a small percentage converted to metabolites. Dexamethasone is metabolized in the liver, primarily by CYP3A4, to inactive metabolites.
Half-LifeThe elimination half-life of ofloxacin is approximately 4-5 hours. The biological half-life of dexamethasone is approximately 36-72 hours.
ExcretionOfloxacin is primarily excreted unchanged in the urine. Dexamethasone metabolites are excreted in the urine and bile.
BioavailabilitySystemic bioavailability after topical ocular administration is low, estimated to be less than 10% for both components.
Onset of ActionThe antibiotic effect of ofloxacin begins within hours of application, while the anti-inflammatory effect of dexamethasone may be noticeable within a few hours to a day.
Peak Plasma TimePeak plasma concentrations after ocular administration are typically low and reached within 1-2 hours.
Duration of ActionThe anti-inflammatory effect of dexamethasone can last up to 24-72 hours, while the antibiotic effect of ofloxacin lasts for several hours after application.

How It Works

This medicine combines the antibiotic action of ofloxacin with the anti-inflammatory action of dexamethasone. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Dexamethasone, a glucocorticoid, binds to intracellular glucocorticoid receptors, which then translocate to the nucleus and modulate gene transcription. This results in reduced production of inflammatory mediators such as prostaglandins, leukotrienes, and cytokines, and decreased migration of inflammatory cells to the eye.

Mechanism Steps

1
Ofloxacin uptake by bacteria: Ofloxacin penetrates the bacterial cell wall and reaches the cytoplasm.
2
Inhibition of DNA gyrase: Ofloxacin binds to DNA gyrase, blocking the supercoiling of bacterial DNA, which is essential for replication.
3
Inhibition of topoisomerase IV: Ofloxacin also inhibits topoisomerase IV, preventing the separation of daughter DNA strands during cell division.
4
Bacterial cell death: The inhibition of these enzymes leads to double-strand DNA breaks and bacterial cell death.
5
Dexamethasone binding to glucocorticoid receptor: Dexamethasone enters ocular cells and binds to cytoplasmic glucocorticoid receptors.
6
Modulation of gene transcription: The dexamethasone-receptor complex moves into the nucleus and alters the transcription of genes involved in inflammation.
7
Reduction of inflammatory mediators: This leads to decreased production of prostaglandins, leukotrienes, and cytokines, and reduced migration of inflammatory cells.

💡 How to Take auto relief eye drop

Strength: Ofloxacin 0.3% w/v + Dexamethasone 0.1% w/v ophthalmic solution

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and look upward.
4Pull down your lower eyelid to create a small pocket.
5Hold the dropper above the eye and squeeze one drop into the pocket.
6Close your eye gently and press the inner corner of your eye with your finger for 1-2 minutes to prevent the medicine from draining into your throat.
7Repeat for the other eye if directed.
8Replace the cap tightly after use.

Dosage Information

Adult DosageThe usual adult dose is one to two drops instilled into the affected eye(s) every 4 to 6 hours, or as directed by your ophthalmologist. For severe infections, the frequency may be increased to every 2 hours initially, then reduced as symptoms improve. The duration of therapy is typically 7 to 10 days, but may vary based on the condition. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are recommended for elderly patients. However, elderly patients may be more susceptible to corticosteroid side effects, such as increased intraocular pressure and cataract formation. Use with caution and monitor closely.
Renal ImpairmentNo dosage adjustment is necessary for renal impairment due to minimal systemic absorption. However, use with caution in patients with severe renal impairment.
Hepatic ImpairmentNo dosage adjustment is necessary for hepatic impairment due to minimal systemic absorption. However, use with caution in patients with severe hepatic impairment.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Use as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of auto relief eye drop

✅ Common Side Effects

Transient eye stinging or burning (Common (5-10%))
Usually resolves within minutes. If persistent, consult your doctor.
Blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery.
Foreign body sensation (Common (5-10%))
Usually temporary. If it continues, inform your doctor.
Eye redness or itching (Uncommon (1-5%))
May indicate irritation or allergy. Consult your doctor if it worsens.

🚨 Serious Side Effects

Allergic reaction (rash, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Increased intraocular pressure (Rare (<0.1%))
Requires monitoring by an eye specialist. Report any eye pain or vision changes.
Secondary eye infection (Rare (<0.1%))
Consult your doctor if new symptoms appear, such as worsening redness or discharge.
Cataract formation (with prolonged use) (Rare (<0.1%))
Regular eye check-ups are advised during long-term use.

⚠️ Rare Side Effects

Corneal deposits
Report to your ophthalmologist if you notice cloudy vision.
Systemic effects like nausea or headache
Usually resolve on their own. If persistent, consult your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other ophthalmic corticosteroids Major
Live vaccines Major
CYP3A4 inhibitors Moderate
NSAIDs Moderate
Anticholinergics Minor

🚨 Major Interactions

  • Other ophthalmic corticosteroids
  • Live vaccines

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • NSAIDs

🍷 Alcohol Interaction

No specific interaction is established between this medicine and alcohol. However, alcohol may worsen eye dryness or irritation. It is advisable to limit alcohol consumption while using this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to ofloxacin, dexamethasone, or any component of the formulation","Viral infections of the eye (e.g., herpes simplex keratitis)","Fungal infections of the eye","Mycobacterial infections of the eye","Untreated purulent ocular infections"]

⚠️ Warnings & Precautions

["Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.","Use with caution in patients with glaucoma due to risk of increased intraocular pressure.","Do not use in patients with a history of herpes simplex keratitis unless directed by an ophthalmologist.","Contact lenses should be removed before application and not reinserted for at least 15 minutes.","Avoid touching the dropper tip to any surface to prevent contamination.","If symptoms do not improve within a few days, consult your doctor.","Systemic absorption may occur; use with caution in patients with renal or hepatic impairment."]

🤱 Lactation Safety

It is not known whether ofloxacin or dexamethasone is excreted in human milk after ocular administration. Systemically administered corticosteroids are excreted in breast milk. Caution should be exercised when using this medicine during breastfeeding. Consult your doctor.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical ocular route. If accidental ingestion occurs, seek medical attention. Symptoms of overdose may include nausea, vomiting, and systemic corticosteroid effects. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are allergic to ofloxacin, dexamethasone, or other fluoroquinolones or corticosteroids. Do not use this medicine if you have a viral, fungal, or mycobacterial eye infection, as it may worsen the condition. Remove contact lenses before applying the drops and wait at least 15 minutes before reinserting them. Avoid touching the dropper tip to your eye or any surface to prevent contamination. Do not use this medicine for longer than prescribed, as prolonged use can increase the risk of side effects. If you are pregnant or breastfeeding, consult your doctor before use. Do not drive or operate machinery if you experience temporary blurred vision after application. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the side effects of corticosteroids, such as increased intraocular pressure and cataract formation. Regular monitoring by an ophthalmologist is advised. No specific dosage adjustment is required, but use with caution.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed. Discuss the potential risks and benefits with your healthcare provider.

🏥 Post-Surgery Considerations

This medicine is often prescribed after eye surgery to prevent infection and reduce inflammation. Use exactly as directed by your surgeon. Do not stop using it without consulting your surgeon. Report any unusual symptoms, such as increased pain or vision changes, immediately.

🦷 Dental Procedures

No specific precautions are required for dental procedures while using this medicine. However, inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Avoid touching or rubbing your eyes to prevent worsening of infection.
🥗
Wash your hands frequently, especially before and after applying the eye drops.
😴
Do not share towels, pillows, or eye makeup with others to prevent spread of infection.
💧
Follow a healthy diet rich in vitamins A, C, and E to support eye health.
🧘
Get adequate sleep to help your body fight infection.
🌞
Avoid wearing contact lenses until the infection has completely resolved.

🏋️ Exercise Considerations

There are no specific exercise restrictions while using this medicine. However, if you experience blurred vision after application, avoid activities that require clear vision, such as swimming or cycling, until your vision returns to normal.

🥗 Diet Recommendations

Include foods rich in vitamin A, such as carrots, spinach, and sweet potatoes.
Stay well hydrated to maintain tear production.
Limit intake of processed foods and sugary drinks that can promote inflammation.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision immediately after application. It is advisable to wait until your vision clears before driving or operating heavy machinery. Otherwise, it should not significantly impact your daily work or activities.

🛑 When to Stop This Medicine

Stop using this medicine only after completing the prescribed course or as directed by your doctor. Do not stop abruptly without consulting your doctor, as this may lead to recurrence of infection. If you experience serious side effects, stop use and seek medical attention immediately.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to increased intraocular pressure, which may result in glaucoma, and can also cause cataract formation. Prolonged use may suppress the immune response in the eye, increasing the risk of secondary infections. Regular monitoring by an ophthalmologist is recommended if long-term use is necessary. Do not use for longer than prescribed without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Can help relieve discomfort and loosen crusts in blepharitis or conjunctivitis.

Evidence: Well-established
Lid hygiene

Regular cleaning of eyelids can help prevent blepharitis.

Evidence: Well-established
Artificial tears

Can provide symptomatic relief for dryness, but do not treat infection.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Corticosteroids may reduce the immune response to vaccines. Consult your doctor before receiving any live vaccine while using this medicine. Inactivated vaccines are generally safe.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Discard 4 weeks after opening

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in your carry-on luggage in its original packaging. Carry a copy of your prescription to avoid issues at customs. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue your regular dosing schedule as closely as possible, but do not double doses. If you are flying, the drops are allowed in quantities greater than 100 ml if accompanied by a prescription.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with bacterial conjunctivitis
She was prescribed this medicine for redness, discharge, and discomfort in her right eye. After using it as directed for 3 days, her symptoms significantly improved. She noted that applying the drops consistently and not missing doses was key to her recovery.
💡 Lesson: Consistent use as prescribed is important for clearing the infection and preventing recurrence.
👤 A 60-year-old man with post-operative inflammation after cataract surgery
He was given this medicine to prevent infection and reduce inflammation after surgery. He experienced mild stinging initially but it subsided. His surgeon monitored his intraocular pressure regularly, which remained normal. He completed the full course without complications.
💡 Lesson: Regular monitoring by an eye specialist is essential during post-operative use to detect any rise in intraocular pressure early.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to feel relief within a few hours to a day, but it is important to complete the full course as prescribed.

Q: Can I use this medicine if I am pregnant?

A: Consult your doctor before use. It should be used only if the potential benefit justifies the potential risk to the fetus.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Can I drive after using this medicine?

A: This medicine may cause temporary blurred vision. Wait until your vision clears before driving or operating machinery.

Q: How should I store this medicine?

A: Store at room temperature (15-30°C), protect from light and freezing, and keep the bottle tightly closed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for my child?
  • What if I forget to use the drops?
  • Can I wear contact lenses while using this medicine?
  • Is it safe to use this medicine with other eye drops?
  • How long does it take to see improvement?
  • Can I use this medicine for a stye?

🔄 Substitutes for auto relief eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any eye infection.
    Fact: This medicine is only effective for bacterial infections and should not be used for viral or fungal eye infections.
  • Myth: It is safe to use this medicine for long periods.
    Fact: Prolonged use can lead to increased intraocular pressure, cataract formation, and secondary infections. Use only as prescribed.
  • Myth: You can stop using this medicine as soon as symptoms improve.
    Fact: You should complete the full course as prescribed to prevent recurrence of infection.

🔄 Alternative Options

Generic Alternatives

  • Ofloxacin 0.3% + Dexamethasone 0.1% ophthalmic solution (generic)

Brand Alternatives

  • Oflox-D Eye Drops
  • Ofloxacin-Dexamethasone Eye Drops
  • Dexoflox Eye Drops

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ofloxacin 0.3% + Dexamethasone 0.1%","route":"Ophthalmic","primary_use":"Bacterial eye infections with inflammation"},{"medicine":"Ciprofloxacin + Dexamethasone","composition":"Ciprofloxacin 0.3% + Dexamethasone 0.1%","route":"Ophthalmic","primary_use":"Bacterial eye infections with inflammation"},{"medicine":"Moxifloxacin + Dexamethasone","composition":"Moxifloxacin 0.5% + Dexamethasone 0.1%","route":"Ophthalmic","primary_use":"Bacterial eye infections with inflammation"}]

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