Auctista M 500mg/20mg Tablet - Uses, Price, Side Effects
What is auctista m 500mg/20mg tablet used for?
Auctista M 500mg/20mg Tablet is a combination medicine used to treat type 2 diabetes mellitus. It contains Metformin and Teneligliptin, which work by improving insulin sensitivity and increasing insulin release, thereby helping to control blood sugar levels. It is usually taken once daily with meals.
- Generic Name: Metformin + Teneligliptin
- Manufacturer: Bioaltus Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ auctista m 500mg/20mg tablet Uses & Benefits
Type 2 diabetes mellitus as an adjunct to diet and exercise, when monotherapy with metformin or teneligliptin is inadequate.
Off-label uses: Polycystic ovary syndrome (metformin), gestational diabetes (metformin), prevention of type 2 diabetes (metformin).
๐ Drug Information
| Generic Name(s) | Metformin + Teneligliptin |
| Brand Name | Afoglip M 500 Tablet ER |
| Manufacturer | Bioaltus Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Antidiabetic (Biguanide + DPP-4 inhibitor) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Metformin: Decreases hepatic glucose production, increases insulin sensitivity; Teneligliptin: Inhibits DPP-4, increasing incretin levels (GLP-1, GIP), enhancing insulin secretion and decreasing glucagon.
Mechanism Steps
๐ก How to Take auctista m 500mg/20mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of auctista m 500mg/20mg tablet
โ Common Side Effects
- Nausea
- Diarrhea
- Abdominal discomfort
- Headache
- Nasopharyngitis
- Hypoglycemia (when combined with other agents)
๐จ Serious Side Effects
- Lactic acidosis
- Pancreatitis
- Severe hypersensitivity reactions
- Acute renal failure
- Hepatic injury
โ ๏ธ Rare Side Effects
- Vitamin B12 deficiency
- Metallic taste
- Urticaria
- Angioedema
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Sulfonylureas | Major | Increased risk of hypoglycemia |
| Corticosteroids | Moderate | Reduced hypoglycemic effect |
| Diuretics | Moderate | Possible hyperglycemia |
๐จ Major Interactions
- Contrast agents (iodinated)
- Cimetidine
- Cationic drugs eliminated by renal tubular secretion
โก Moderate Interactions
- Insulin
- Sulfonylureas
- Thiazolidinediones
- Alcohol
โน๏ธ Minor Interactions
- Furosemide
- Nifedipine
- Topiramate
๐ฝ๏ธ Food Interactions
Alcohol, High-fat meals may affect absorption
๐ท Alcohol Interaction
Increased risk of lactic acidosis with metformin
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe renal impairment (eGFR <30 mL/min), metabolic acidosis, acute or chronic metabolic acidosis, diabetic ketoacidosis, hypersensitivity, hepatic impairment, acute myocardial infarction, sepsis.
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function (eGFR), liver function, vitamin B12 levels (long-term metformin), signs of lactic acidosis.
๐คฑ Lactation Safety
Metformin excreted in milk; Teneligliptin unknown; avoid breastfeeding.
๐ Overdose Management
Supportive care; monitor blood glucose and lactate; hemodialysis may remove metformin.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if next dose is due.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.