aturis ez 10mg/10mg tablet
What is aturis ez 10mg/10mg tablet used for?
Aztor EZ Tablet (Atorvastatin + Ezetimibe) is used to treat CARDIAC. It contains Atorvastatin (10mg) + Ezetimibe (10mg), which Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Ezetimi. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atorvastatin + Ezetimibe
- Manufacturer: Curis Lifecare
- Form: Allopathy
- Pregnancy Category: X
- Prescription Required: Yes
๐ aturis ez 10mg/10mg tablet Uses & Benefits
Primary hypercholesterolemia, mixed dyslipidemia, homozygous familial hypercholesterolemia, prevention of cardiovascular events.
Off-label uses: Chronic kidney disease, non-alcoholic fatty liver disease (NAFLD), post-transplant hyperlipidemia.
๐ Drug Information
| Generic Name(s) | Atorvastatin + Ezetimibe |
| Brand Name | Aztor EZ Tablet |
| Manufacturer | Curis Lifecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihyperlipidemic Agents |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Ezetimibe inhibits intestinal cholesterol absorption via the NPC1L1 receptor.
Mechanism Steps
๐ก How to Take aturis ez 10mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aturis ez 10mg/10mg tablet
โ Common Side Effects
- Nasopharyngitis
- Arthralgia
- Diarrhea
- Pain in extremity
- Urinary tract infection
๐จ Serious Side Effects
- Rhabdomyolysis
- Myopathy
- Hepatotoxicity
- Pancreatitis
- Angioedema
โ ๏ธ Rare Side Effects
- Interstitial lung disease
- Peripheral neuropathy
- Memory loss
- Gynecomastia
- Tendon rupture
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cyclosporine | Major | Increased risk of myopathy/rhabdomyolysis |
| Gemfibrozil | Major | Increased risk of myopathy/rhabdomyolysis |
| Warfarin | Moderate | Increased INR and bleeding risk |
| Grapefruit juice | Moderate | Increased atorvastatin plasma levels |
๐จ Major Interactions
- Cyclosporine
- Gemfibrozil
- Fibrates
- Macrolide antibiotics
- Azole antifungals
- HIV protease inhibitors
- Nefazodone
โก Moderate Interactions
- Warfarin
- Digoxin
- Oral contraceptives
- Colchicine
- Amiodarone
- Verapamil
- Diltiazem
- Grapefruit juice
โน๏ธ Minor Interactions
- Antacids
- Fenofibrate
- Niacin
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin exposure; avoid large quantities. High-fat meals reduce absorption.
๐ท Alcohol Interaction
May increase risk of hepatotoxicity; limit alcohol consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to any component.
๐ Monitoring Parameters
Lipid profile, liver function tests (ALT, AST), creatine kinase (CK) if muscle symptoms occur.
๐คฑ Lactation Safety
Contraindicated; may be excreted in breast milk.
๐ Overdose Management
Symptomatic and supportive; no specific antidote. Monitor liver function and CK levels.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
This medicine was effective for me. I followed the doctor's advice.