atrop eye drop

4.5 (15 reviews)

Atropine (1% w/v)

🏭 Aurolab 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is atrop eye drop used for?

Atropine Sulphate Injection (Atropine) is used to treat OPHTHAL. It contains Atropine (1% w/v), which Competitive antagonist of acetylcholine at muscarinic receptors, blocking parasy. Always consult your doctor before use. Take as prescribed.

Generic Name: Atropine
Manufacturer: Aurolab
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 atrop eye drop Uses & Benefits

Preoperative medication to reduce secretions, treatment of bradycardia, organophosphate poisoning, ophthalmic examinations (mydriasis/cycloplegia).

Off-label uses: Reduction of hypersalivation, treatment of asthma (historical), biliary colic.

📋 Drug Information

Generic Name(s)	Atropine
Brand Name	Atropine Sulphate Injection
Manufacturer	Aurolab
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OPHTHAL
Action Class	Anticholinergics
Route of Administration	Intravenous, intramuscular, subcutaneous; ophthalmic (eye drops).
Storage	Store at 20-25°C (68-77°F); protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after intramuscular or subcutaneous injection; well absorbed from gastrointestinal tract but not used orally for systemic effects.

DistributionWidely distributed throughout the body; crosses blood-brain barrier and placenta.

Protein BindingApproximately 50% bound to plasma proteins.

MetabolismHepatic metabolism via enzymatic hydrolysis.

Half-LifeApproximately 2-3 hours.

ExcretionRenal excretion (about 30-50% unchanged) with small amounts in feces.

BioavailabilityNot applicable for injection; 100% bioavailability via IV route.

Onset of ActionRapid (within minutes) after IV administration; 15-30 minutes after IM/SC.

Peak Plasma Time15-30 minutes after IM injection.

Duration of Action4-6 hours depending on dose and route.

How It Works

Competitive antagonist of acetylcholine at muscarinic receptors, blocking parasympathetic effects.

Mechanism Steps

1Atropine binds to muscarinic receptors

2Blocks acetylcholine binding

3Prevents parasympathetic nerve transmission

💡 How to Take atrop eye drop

Follow your doctor's prescription exactly.

⚠️ Side Effects of atrop eye drop

✅ Common Side Effects

Dry mouth
Blurred vision
Photophobia
Tachycardia
Constipation
Urinary retention

🚨 Serious Side Effects

Severe tachycardia
Arrhythmias
Acute glaucoma
Central anticholinergic syndrome (confusion, hallucinations)

⚠️ Rare Side Effects

Anaphylaxis
Paralytic ileus
Hyperthermia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Anticholinesterases	Major	Antagonism of effects; used in organophosphate poisoning.
Potassium chloride	Major	Increased risk of gastrointestinal lesions.
Metoclopramide	Major	Antagonism of gastrointestinal motility effects.
Antihistamines	Moderate	Additive anticholinergic effects.
Phenothiazines	Moderate	Increased anticholinergic side effects.
Tricyclic antidepressants	Moderate	Additive anticholinergic effects.
Digoxin	Minor	Increased digoxin absorption due to slowed GI motility.
Corticosteroids	Minor	Possible increased intraocular pressure.

🚨 Major Interactions

Anticholinesterases
Potassium chloride
Metoclopramide

⚡ Moderate Interactions

Antihistamines
Phenothiazines
Tricyclic antidepressants

ℹ️ Minor Interactions

Digoxin
Corticosteroids

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

May increase CNS depression; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, glaucoma, tachycardia, thyrotoxicosis, obstructive GI disorders, myasthenia gravis (relative).

📊 Monitoring Parameters

Heart rate, blood pressure, intraocular pressure, urinary output, mental status.

🤱 Lactation Safety

Excreted in breast milk in small amounts; use with caution.

💊 Overdose Management

Supportive care; physostigmine as antidote for severe anticholinergic syndrome.

⏰ Missed Dose

Not applicable for acute use; administer as needed.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for atrop eye drop

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Alternative brands with exact same active ingredient (Atropine (1% w/v)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026