atozim-fr tablet - Atorvastatin (10mg) + Fenofibrate (160mg) medicine

Atozim FR Tablet - Uses, Price, Side Effects

4.6 (16 reviews)
🏭 Adiza Healthcare πŸ“¦ Varies by brand πŸ’Š Allopathy πŸ“… Updated: Aug 23, 2026
⚠️ Hepatotoxicity Risk πŸ“‹ Prescription Required πŸ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is atozim-fr tablet used for?

Atozim FR Tablet is a combination of Atorvastatin (10mg) and Fenofibrate (160mg) used to lower high cholesterol and triglyceride levels. Atorvastatin works by blocking an enzyme that produces cholesterol in the liver, while Fenofibrate reduces triglycerides and increases good cholesterol. It is prescribed when diet and exercise alone are not enough to control lipid levels.

  • Generic Name: Atorvastatin + Fenofibrate
  • Manufacturer: Adiza Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
πŸ’‘ Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

πŸ’Š atozim-fr tablet Uses & Benefits

Primary hypercholesterolemia, mixed dyslipidemia, hypertriglyceridemia.

Off-label uses: Secondary prevention of cardiovascular events, non-alcoholic fatty liver disease.

πŸ“‹ Drug Information

Generic Name(s)Atorvastatin + Fenofibrate
Brand NameAtorlip-F Tablet
ManufacturerAdiza Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassLipid-lowering agents (Statin + Fibrate)
Route of AdministrationOral
StorageStore at 20-25Β°C, protect from light and moisture.
Shelf LifeAs per manufacturer

πŸ”¬ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAtorvastatin: Rapidly absorbed after oral administration; Fenofibrate: Well absorbed, absorption enhanced with food.
DistributionAtorvastatin: Extensively distributed to tissues; Fenofibrate: Highly bound to albumin.
Protein BindingAtorvastatin: β‰₯98%; Fenofibrate: ~99%
MetabolismAtorvastatin: Hepatic via CYP3A4; Fenofibrate: Hydrolysis to fenofibric acid, then glucuronidation.
Half-LifeAtorvastatin: ~14 hours; Fenofibrate: ~20 hours (fenofibric acid)
ExcretionAtorvastatin: Biliary (feces); Fenofibrate: Renal (urine) as metabolites.
BioavailabilityAtorvastatin: ~14%; Fenofibrate: ~30% (increased with food)
Onset of ActionAtorvastatin: 1-2 weeks for lipid changes; Fenofibrate: Several days to weeks.
Peak Plasma TimeAtorvastatin: 1-2 hours; Fenofibrate: 6-8 hours (fenofibric acid)
Duration of ActionAtorvastatin: Up to 24 hours; Fenofibrate: Up to 24 hours.

How It Works

Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofibrate activates PPARΞ±, increasing lipolysis and VLDL clearance.

Mechanism Steps

1Atorvastatin competitively inhibits HMG-CoA reductase, reducing mevalonate and cholesterol synthesis.
2Fenofibrate activates PPARΞ±, increasing lipoprotein lipase activity and fatty acid oxidation.
3Combined effect: Decreased hepatic VLDL secretion, increased clearance of triglycerides, and upregulation of LDL receptors.

πŸ’‘ How to Take atozim-fr tablet

Follow your doctor's prescription exactly.

Dosage Timeline

πŸŒ… Morning βœ… β˜€οΈ Afternoon ❌ πŸŒ† Evening βœ… πŸŒ™ Night ❌

⚠️ Side Effects of atozim-fr tablet

βœ… Common Side Effects

  • Myalgia
  • Diarrhea
  • Nasopharyngitis
  • Headache
  • Abdominal pain

🚨 Serious Side Effects

  • Rhabdomyolysis
  • Hepatotoxicity
  • Pancreatitis
  • Renal failure
  • Angioedema

⚠️ Rare Side Effects

  • Peripheral neuropathy
  • Interstitial lung disease
  • Tendon rupture
  • Gynecomastia

Consult your doctor if you experience any unusual symptoms.

πŸ”¬ Drug Interactions

⚠️ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Cyclosporine Major Increased risk of nephrotoxicity and myopathy
Gemfibrozil Major Increased risk of myopathy/rhabdomyolysis
Colchicine Moderate Increased risk of myopathy
Fibrates Moderate Additive effect on lipid lowering, increased risk of gallstones

🚨 Major Interactions

  • Warfarin
  • Cyclosporine
  • Gemfibrozil
  • Macrolide antibiotics
  • Azole antifungals
  • HIV protease inhibitors

⚑ Moderate Interactions

  • Digoxin
  • Oral contraceptives
  • Colchicine
  • Fibrates (other)
  • Niacin

ℹ️ Minor Interactions

  • Antacids
  • Rifampin
  • St. John's Wort

🍽️ Food Interactions

Grapefruit juice increases atorvastatin levels; high-fat meal increases fenofibrate absorption.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid excessive alcohol.

πŸ›‘οΈ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

🚫 Contraindications

Active liver disease, unexplained LFT elevations, pregnancy, lactation, hypersensitivity, severe renal impairment.

πŸ“Š Monitoring Parameters

Lipid profile, LFTs, CPK, renal function, INR if on warfarin.

🀱 Lactation Safety

Contraindicated; excreted in milk.

πŸ’Š Overdose Management

Supportive care; monitor liver and renal function; no specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip if close.

πŸ‘¨β€βš•οΈ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

πŸ”— View Profile

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

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