atosta 40 tablet - Atorvastatin (40mg) medicine

Atosta 40 Tablet - Uses, Price, Side Effects

4.5 (16 reviews)
Atorvastatin (40mg)
๐Ÿญ Shrrishti Health Care Products Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is atosta 40 tablet used for?

Atosta 40 Tablet contains Atorvastatin 40mg, a statin used to lower high cholesterol and reduce the risk of heart attack and stroke. It works by blocking an enzyme that produces cholesterol in the liver, thereby decreasing LDL (bad) cholesterol and triglycerides while increasing HDL (good) cholesterol.

  • Generic Name: Atorvastatin
  • Manufacturer: Shrrishti Health Care Products Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: X
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š atosta 40 tablet Uses & Benefits

Hypercholesterolemia, mixed dyslipidemia, prevention of cardiovascular events.

Off-label uses: Familial hypercholesterolemia, nephrotic syndrome, post-transplant hyperlipidemia.

๐Ÿ“‹ Drug Information

Generic Name(s)Atorvastatin
Brand NameAtorva
ManufacturerShrrishti Health Care Products Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassHMG CoA inhibitors (statins)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations occur within 1-2 hours. Food decreases the rate and extent of absorption.
DistributionDistributed to tissues; crosses placenta and is excreted in breast milk.
Protein Bindingโ‰ฅ98% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP3A4 to active ortho- and para-hydroxylated metabolites.
Half-LifeApproximately 14 hours; active metabolites have half-life of 20-30 hours.
ExcretionPrimarily eliminated in bile (feces); less than 2% excreted in urine.
BioavailabilityApproximately 14% due to first-pass metabolism.
Onset of ActionWithin 2 weeks of therapy.
Peak Plasma Time1-2 hours.
Duration of Action24 hours (once-daily dosing).

How It Works

Competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis.

Mechanism Steps

1Atorvastatin competitively inhibits HMG-CoA reductase, preventing conversion of HMG-CoA to mevalonate.
2Reduced mevalonate leads to decreased cholesterol synthesis in the liver.
3Decreased intrahepatic cholesterol triggers upregulation of LDL receptors on hepatocytes.

๐Ÿ’ก How to Take atosta 40 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of atosta 40 tablet

โœ… Common Side Effects

  • Nasopharyngitis
  • Diarrhea
  • Arthralgia
  • Urinary tract infection
  • Nausea
  • Muscle pain

๐Ÿšจ Serious Side Effects

  • Rhabdomyolysis
  • Myopathy
  • Hepatotoxicity
  • Pancreatitis
  • Peripheral neuropathy

โš ๏ธ Rare Side Effects

  • Interstitial lung disease
  • Gynecomastia
  • Memory loss
  • Depression
  • Tendon rupture

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Clarithromycin Major Increased risk of myopathy/rhabdomyolysis
Grapefruit juice Moderate Increased atorvastatin plasma concentration
Digoxin Minor Slight increase in digoxin levels

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, protease inhibitors)
  • Cyclosporine
  • Gemfibrozil
  • Warfarin

โšก Moderate Interactions

  • Digoxin
  • Oral contraceptives
  • Colchicine
  • Fibrates (other than gemfibrozil)
  • Niacin

โ„น๏ธ Minor Interactions

  • Antacids
  • Grapefruit juice
  • Rifampin

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase plasma levels; avoid large quantities.

๐Ÿท Alcohol Interaction

Excessive alcohol consumption may increase risk of hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category X

๐Ÿšซ Contraindications

Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to atorvastatin.

๐Ÿ“Š Monitoring Parameters

Lipid profile, liver function tests (baseline and periodically), creatine kinase if muscle symptoms occur.

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk.

๐Ÿ’Š Overdose Management

No specific antidote; symptomatic and supportive care. Monitor liver function and CK levels.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for atosta 40 tablet

View All

Alternative brands with exact same active ingredient (Atorvastatin (40mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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