Atorest 40mg Tablet - Uses, Price, Side Effects
What is atorest 40mg tablet used for?
Atorest 40mg Tablet contains Atorvastatin, a statin used to lower high cholesterol and triglycerides, reducing the risk of heart attack and stroke. It works by blocking an enzyme that produces cholesterol in the liver, thereby decreasing LDL (bad) cholesterol and increasing HDL (good) cholesterol.
- Generic Name: Atorvastatin
- Manufacturer: Akums Drugs & Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: X
- Prescription Required: Yes
๐ atorest 40mg tablet Uses & Benefits
Hypercholesterolemia, mixed dyslipidemia, prevention of cardiovascular events.
Off-label uses: Familial hypercholesterolemia, nephrotic syndrome, post-transplant hyperlipidemia.
๐ Drug Information
| Generic Name(s) | Atorvastatin |
| Brand Name | Atorva |
| Manufacturer | Akums Drugs & Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG CoA inhibitors (statins) |
| Route of Administration | Oral. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis.
Mechanism Steps
๐ก How to Take atorest 40mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of atorest 40mg tablet
โ Common Side Effects
- Nasopharyngitis
- Diarrhea
- Arthralgia
- Urinary tract infection
- Nausea
- Muscle pain
๐จ Serious Side Effects
- Rhabdomyolysis
- Myopathy
- Hepatotoxicity
- Pancreatitis
- Peripheral neuropathy
โ ๏ธ Rare Side Effects
- Interstitial lung disease
- Gynecomastia
- Memory loss
- Depression
- Tendon rupture
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Cyclosporine | Major | Increased risk of myopathy/rhabdomyolysis |
| Gemfibrozil | Major | Increased risk of myopathy/rhabdomyolysis |
| Erythromycin | Moderate | Increased atorvastatin levels |
| Digoxin | Moderate | Increased digoxin levels |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, protease inhibitors)
- Cyclosporine
- Gemfibrozil
- Warfarin
โก Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Fibrates (other than gemfibrozil)
- Niacin
โน๏ธ Minor Interactions
- Antacids
- Grapefruit juice
- Rifampin
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase plasma levels; avoid large quantities.
๐ท Alcohol Interaction
Excessive alcohol consumption may increase risk of hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to atorvastatin.
๐ Monitoring Parameters
Lipid profile, liver function tests (baseline and periodically), creatine kinase if muscle symptoms occur.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
No specific antidote; symptomatic and supportive care. Monitor liver function and CK levels.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for atorest 40mg tablet
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Medical Note: Always consult your doctor before switching medications.