Atiza M Syrup - Uses, Price, Side Effects
What is atiza m syrup used for?
Atiza M Syrup is a combination of Levocetirizine (an antihistamine) and Montelukast (a leukotriene receptor antagonist). It is used to relieve symptoms of allergic rhinitis such as sneezing, runny nose, and itching, and to prevent asthma attacks. Levocetirizine blocks histamine, while Montelukast reduces airway inflammation and constriction.
- Generic Name: Levocetirizine + Montelukast
- Manufacturer: Ambreyo Lifesciences
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ atiza m syrup Uses & Benefits
Seasonal and perennial allergic rhinitis; asthma prophylaxis
Off-label uses: Urticaria, Eosinophilic esophagitis
๐ Drug Information
| Generic Name(s) | Levocetirizine + Montelukast |
| Brand Name | Allercet-M Tablet |
| Manufacturer | Ambreyo Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Leukotriene Receptor Antagonist |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levocetirizine selectively inhibits peripheral H1 receptors; Montelukast antagonizes leukotriene D4 at CysLT1 receptors
Mechanism Steps
๐ก How to Take atiza m syrup
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of atiza m syrup
โ Common Side Effects
- Headache
- Drowsiness
- Dry mouth
- Cough
- Pharyngitis
๐จ Serious Side Effects
- Angioedema
- Anaphylaxis
- Neuropsychiatric events (agitation, depression)
โ ๏ธ Rare Side Effects
- Hepatitis
- Thrombocytopenia
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased INR and bleeding risk |
| Theophylline | Moderate | Increased risk of theophylline toxicity |
| Erythromycin | Moderate | Decreased metabolism of montelukast |
| Rifampin | Moderate | Reduced efficacy of montelukast |
| Phenobarbital | Moderate | Reduced efficacy of montelukast |
๐จ Major Interactions
- CYP3A4 inducers (e.g., Rifampin)
- CYP2C9 inducers (e.g., Phenobarbital)
โก Moderate Interactions
- Gemfibrozil
- Itraconazole
- Warfarin
โน๏ธ Minor Interactions
- Theophylline
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Montelukast absorption decreased by high-fat meal; take on empty stomach
๐ท Alcohol Interaction
Levocetirizine may potentiate CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe renal impairment (CrCl <10 mL/min) for levocetirizine
๐ Monitoring Parameters
Renal function, hepatic function, signs of neuropsychiatric events
๐คฑ Lactation Safety
Levocetirizine excreted in breast milk; caution advised
๐ Overdose Management
Symptomatic and supportive; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double