Athrovas HC Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing, which may indicate a severe allergic reaction.
- Sudden vision loss or changes, especially if you have Leber's disease.
- Severe skin rash with blistering or peeling, which may be a sign of a serious skin reaction.
- Persistent vomiting or severe diarrhea leading to dehydration.
- Unusual bleeding or bruising, which may indicate a blood disorder.
- Chest pain, palpitations, or irregular heartbeat.
- Severe headache with confusion or weakness on one side of the body.
- Yellowing of the skin or eyes (jaundice).
If experiencing severe symptoms, call emergency services immediately.
What is athrovas hc tablet used for?
This medicine is a prescription supplement containing L-Methyl Folate (1 mg) and Methylcobalamin (1500 mcg). It is used to treat vitamin B12 and folate deficiencies, peripheral neuropathy, and certain types of anemia. It works by providing the active forms of these vitamins, which support nerve health, red blood cell production, and normal homocysteine levels. The usual dose is one tablet daily, but it must be individualized by a doctor.
- Generic Name: L-Methyl Folate (1mg) + Methylcobalamin/Mecobalamin (1500mcg)
- Manufacturer: Oldmed Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 athrovas hc tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ल-मिथाइल फोलेट और मिथाइलकोबालामिन का संयोजन है, जिसका उपयोग विटामिन बी12 और फोलेट की कमी को पूरा करने के लिए किया जाता है। यह नसों की समस्याओं जैसे झुनझुनी, सुन्नपन और जलन में राहत देने में मदद करती है। डायबिटीज से होने वाली न्यूरोपैथी में भी यह दवा फायदेमंद मानी जाती है। इसके अलावा, यह खून की कमी (एनीमिया) में सुधार करती है और शरीर में हॉमोसिस्टीन के स्तर को कम करने में सहायक है। जिन लोगों में MTHFR जीन की समस्या होती है, उनके लिए यह दवा विशेष रूप से उपयोगी है क्योंकि इसमें फोलेट पहले से ही सक्रिय रूप में मौजूद होता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: यह दवा आमतौर पर सुरक्षित मानी जाती है क्योंकि इसमें पानी में घुलनशील विटामिन होते हैं। अधिकांश लोगों को कोई दुष्प्रभाव नहीं होता। कभी-कभी हल्की मतली, पेट में असहजता, या मुँह में धातु जैसा स्वाद महसूस हो सकता है। कुछ लोगों को सिरदर्द, चक्कर आना, या हल्का दस्त हो सकता है। बहुत कम मामलों में त्वचा पर खुजली वाले दाने या एलर्जी हो सकती है। गंभीर दुष्प्रभाव बहुत दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, या गंभीर त्वचा प्रतिक्रिया हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा कम या ज्यादा न करें। गोली को पानी के साथ पूरा निगलें, और इसे भोजन के साथ लेना बेहतर होता है ताकि पेट में जलन न हो। अगर आपको किडनी या लीवर की बीमारी है, तो डॉक्टर को जरूर बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के यह दवा न लें। शराब का सेवन न करें क्योंकि इससे विटामिन बी12 और फोलेट का अवशोषण कम हो सकता है। दवा को ठंडी और सूखी जगह पर रखें, धूप से बचाएं, और बच्चों की पहुंच से दूर रखें। एक्सपायरी डेट के बाद दवा का इस्तेमाल न करें।
💊 athrovas hc tablet Uses & Benefits
[{"condition":"Vitamin B12 deficiency","description":"This medicine provides methylcobalamin, the active form of vitamin B12, to correct deficiency and prevent complications such as anemia and nerve damage.","evidence":"Well-established"},{"condition":"Folate deficiency","description":"L-Methyl Folate supplies the active form of folate, which is essential for red blood cell formation and normal cell division.","evidence":"Well-established"},{"condition":"Peripheral neuropathy","description":"This medicine supports nerve repair and reduces symptoms like tingling, numbness, and burning in the hands and feet, especially when caused by vitamin deficiencies.","evidence":"Moderate"},{"condition":"Diabetic neuropathy","description":"Methylcobalamin and L-Methyl Folate may help improve nerve function and reduce pain in people with diabetes-related nerve damage.","evidence":"Moderate"},{"condition":"Hyperhomocysteinemia","description":"This medicine helps lower elevated homocysteine levels, which is a risk factor for heart disease and stroke, by supporting methylation pathways.","evidence":"Moderate"},{"condition":"MTHFR gene mutation-related folate deficiency","description":"People with MTHFR gene variations may not convert folic acid efficiently; L-Methyl Folate bypasses this step and provides usable folate directly.","evidence":"Limited"},{"condition":"Megaloblastic anemia","description":"This medicine helps treat certain types of anemia caused by vitamin B12 or folate deficiency, supporting healthy red blood cell production.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Mood support in depression","description":"Some doctors prescribe L-Methyl Folate and Methylcobalamin as add-on therapy for depression, especially in people with low folate or B12 levels.","evidence":"Limited"},{"condition":"Cognitive support in elderly","description":"This medicine may be used off-label to support memory and cognitive function in older adults with vitamin deficiencies.","evidence":"Limited"},{"condition":"Migraine prophylaxis","description":"L-Methyl Folate has been studied for reducing migraine frequency in people with MTHFR gene variants, but evidence is not strong enough for routine use.","evidence":"Limited"}]
Primary treatment for: Vitamin B12 and folate deficiency
Also treats: Peripheral neuropathy, Diabetic neuropathy, Megaloblastic anemia, Hyperhomocysteinemia, MTHFR gene mutation-related folate deficiency
📋 Drug Information
| Generic Name(s) | L-Methyl Folate (1mg) + Methylcobalamin/Mecobalamin (1500mcg) |
| Brand Name | athrovas hc tablet |
| Manufacturer | Oldmed Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F to 86°F). Keep it in a cool, dry place away from direct sunlight and moisture. Do not store it in the bathroom. Keep the tablets in their original container with the lid tightly closed. Do not remove the desiccant pack if present. Keep out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Always check the expiry date printed on the pack. Do not use the medicine after the expiry date. Proper storage ensures the medicine remains effective until the expiry date. |
| WHO Guideline | Not established from the available information. The World Health Organization has general guidelines on vitamin B12 and folate supplementation, but specific recommendations for this combination product are not available. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has guidelines on recommended dietary allowances for vitamins, but specific recommendations for this combination product are not available. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by supplying two active coenzyme forms of B vitamins that are directly usable by the body. L-Methyl Folate is the reduced, active form of folate that participates in one-carbon transfer reactions. It donates methyl groups in the conversion of homocysteine to methionine, a reaction catalyzed by methionine synthase. Methylcobalamin acts as a cofactor for methionine synthase and also for methylmalonyl-CoA mutase. By supporting these enzymes, the medicine helps maintain normal homocysteine levels, supports DNA and RNA synthesis, and promotes healthy myelin formation around nerves. Methylcobalamin also helps in the production of red blood cells in the bone marrow and supports normal nerve signaling. Together, these actions correct deficiencies, improve nerve health, and support overall cellular function.
Mechanism Steps
💡 How to Take athrovas hc tablet
Strength: This medicine is available as an immediate-release tablet containing L-Methyl Folate 1 mg and Methylcobalamin 1500 mcg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably with a meal. However, the exact dose and duration depend on the specific condition being treated, your age, weight, kidney and liver function, and your response to treatment. For vitamin B12 deficiency, the dose may be one tablet daily for several weeks, followed by a maintenance dose. For neuropathy, it may be taken for several months. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients (above 65 years) can usually take the same adult dose of this medicine. However, because kidney function may decline with age, your doctor may adjust the dose if you have kidney problems. Regular monitoring of vitamin levels and kidney function is advised. Always follow your doctor's instructions. |
| Renal Impairment | In patients with mild to moderate kidney disease, no dose adjustment is usually needed. In severe kidney disease or those on dialysis, the dose may need to be adjusted because excretion of these vitamins may be reduced. Your doctor will determine the appropriate dose based on your kidney function tests. |
| Hepatic Impairment | In patients with mild to moderate liver disease, no dose adjustment is usually needed. In severe liver disease, your doctor may monitor your liver function and adjust the dose if necessary. Always inform your doctor about any liver condition before taking this medicine. |
| Maximum Daily Dose | The maximum daily dose of this medicine is generally one tablet (L-Methyl Folate 1 mg + Methylcobalamin 1500 mcg) per day, unless otherwise prescribed by your doctor. Do not exceed the prescribed dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of athrovas hc tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | |
| Levodopa | Major | |
| Phenytoin | Major | |
| Chloramphenicol | Major | |
| Omeprazole | Moderate | |
| Metformin | Moderate | |
| Colchicine | Moderate | |
| Sulfasalazine | Moderate | |
| Antacids | Minor | |
| Vitamin C supplements | Minor |
🚨 Major Interactions
- Methotrexate
- Levodopa
- Phenytoin
- Chloramphenicol
⚡ Moderate Interactions
- Proton pump inhibitors (e.g., omeprazole)
- Metformin
- Colchicine
- Sulfasalazine
🍷 Alcohol Interaction
Drinking alcohol while taking this medicine can reduce the absorption of both L-Methyl Folate and Methylcobalamin. Chronic heavy drinking can lead to severe deficiencies of these vitamins and worsen nerve damage. It is best to avoid alcohol or limit it to occasional small amounts. If you drink regularly, tell your doctor so they can monitor your vitamin levels and adjust the dose if needed.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to L-Methyl Folate, Methylcobalamin, or any component of the tablet","Leber's disease (hereditary optic neuropathy) because methylcobalamin can worsen vision loss","Use in children unless specifically prescribed by a pediatrician","Severe untreated vitamin B12 deficiency with neurological involvement should be evaluated by a doctor before starting this medicine"]
⚠️ Warnings & Precautions
["Do not take this medicine without a doctor's prescription.","Inform your doctor if you have kidney disease, liver disease, or any chronic illness.","Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol while taking this medicine.","Do not take more than the prescribed dose.","Keep out of reach of children.","If you have Leber's disease, do not take this medicine.","If you experience any allergic reaction, stop the medicine and seek medical help immediately.","Regular blood tests may be needed to monitor your vitamin levels.","Do not use this medicine as a substitute for a balanced diet."]
🤱 Lactation Safety
L-Methyl Folate and Methylcobalamin are safe to use during breastfeeding when taken at recommended doses. Both vitamins are naturally present in breast milk and are important for infant development. However, consult your doctor before starting this medicine while breastfeeding to ensure the dose is appropriate for you and your baby.
💊 Overdose Management
This medicine contains water-soluble vitamins, and overdose is unlikely to cause serious harm. However, taking too much may cause nausea, stomach upset, or diarrhea. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is usually supportive and may include drinking plenty of fluids. In case of accidental overdose in children, seek emergency medical care right away.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided it is not almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, call your doctor or pharmacist for advice.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose on your own. Swallow the tablet whole with a glass of water, preferably with a meal to improve absorption and reduce stomach upset. If you have kidney disease, liver disease, or any chronic illness, tell your doctor before starting this medicine. Do not take this medicine if you are allergic to L-Methyl Folate, Methylcobalamin, or any ingredient in the tablet. If you are pregnant or planning pregnancy, inform your doctor so that the dose can be adjusted safely. If you are breastfeeding, consult your doctor before use. Avoid drinking alcohol heavily while taking this medicine because alcohol can interfere with vitamin B12 and folate absorption. Keep all follow-up appointments and get your blood tests done as advised. Store the tablets in a cool, dry place away from direct sunlight and out of reach of children. Do not use the medicine after the expiry date printed on the pack.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients can take this medicine, but they may be more prone to vitamin B12 deficiency due to reduced stomach acid and absorption. Kidney function may also decline with age, so dose adjustment may be needed if kidney disease is present. Regular monitoring of vitamin levels and kidney function is advised. Elderly patients should be cautious about dizziness and falls, especially if they have neuropathy. Always follow your doctor's instructions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, talk to your doctor about this medicine. Folate is essential for preventing neural tube defects in the developing baby, and vitamin B12 is important for fetal development. Your doctor may recommend continuing this medicine or adjusting the dose. Do not start or stop this medicine without medical advice. A balanced diet rich in folate and B12 is also important.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist about this medicine. In most cases, you can continue taking it before and after surgery. However, if you are advised to fast before surgery, take your medicine after the procedure as directed by your doctor. This medicine does not increase bleeding risk. After surgery, it may help with recovery by supporting nerve health and red blood cell production.
🦷 Dental Procedures
This medicine does not interact with dental anesthetics or procedures. You can continue taking it before and after dental work. However, if you are having a procedure that requires sedation, inform your dentist about all medicines you are taking. There is no need to stop this medicine for routine dental cleanings or fillings.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine. However, if you have peripheral neuropathy, you may have reduced sensation in your feet, which can increase the risk of injury. Wear well-fitting, protective footwear and check your feet daily for cuts, blisters, or sores. Avoid high-impact activities that could cause falls. If you experience dizziness or balance problems, avoid activities that require balance until you feel better. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness or drowsiness after taking it, avoid driving or operating heavy machinery until you feel normal. Most people can continue their daily activities without any problems. If your job involves fine motor skills or balance, be cautious until you know how the medicine affects you. Inform your employer about your condition if you need any accommodations.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will decide when it is safe to stop based on your vitamin levels, symptoms, and overall health. If you experience serious side effects like an allergic reaction, stop the medicine immediately and seek medical help. If you become pregnant or plan to become pregnant, consult your doctor before stopping or continuing. Never stop abruptly on your own.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when taken as prescribed. Both L-Methyl Folate and Methylcobalamin are water-soluble vitamins, and excess amounts are excreted in urine. However, long-term high-dose use should be monitored by a doctor. Regular blood tests may be needed to check vitamin levels and ensure they are within normal range. In people with Leber's disease, long-term use of methylcobalamin can worsen vision, so it must be avoided. If you have kidney disease, long-term use may require dose adjustment. Always follow your doctor's advice regarding duration of treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing intake of foods rich in vitamin B12 and folate can help correct mild deficiencies.
Evidence: Well-establishedFor severe deficiency or absorption problems, injections may be needed instead of oral tablets.
Evidence: Well-establishedCan help improve balance, strength, and mobility in people with neuropathy.
Evidence: Well-establishedSome people find acupuncture helpful for nerve pain, but evidence is mixed.
Evidence: LimitedA device that delivers mild electrical currents to reduce nerve pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interfere with vaccines. You can receive vaccinations while taking this medicine. However, if you are scheduled for a vaccine, inform your healthcare provider about all medicines you are taking. There are no known interactions between this medicine and vaccines.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified on the label.
✅ DO
Keep in the original container with the lid tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you in case you need to show it to customs or security. Store the tablets in a cool, dry place, away from direct sunlight. If you are traveling across time zones, continue taking your dose at the same time each day according to your home schedule, or adjust gradually as advised by your doctor. Carry enough supply for your entire trip, plus a few extra days in case of delays. Do not pack it in checked luggage; keep it in your carry-on bag.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel more energetic within 1 to 2 weeks if you were deficient. For nerve symptoms like tingling and numbness, it may take 4 to 12 weeks to notice improvement. Continue taking it as prescribed.
A: It is best to take this medicine with a meal to improve absorption and reduce stomach upset. If you take it on an empty stomach and feel nauseous, try taking it with food next time.
A: No, this medicine is not a steroid. It is a nutritional supplement containing vitamins B12 and folate. It does not cause the side effects associated with steroids.
A: Do not stop without consulting your doctor. Even if you feel better, your vitamin levels may still be low. Your doctor will decide when it is safe to stop.
A: If you remember within 12 hours, take the missed dose. If more than 12 hours have passed, skip it and take your next dose at the regular time. Do not double the dose.
A: This medicine can interact with certain drugs like methotrexate, levodopa, and phenytoin. Always inform your doctor about all medicines you are taking before starting this medicine.
A: Folate and vitamin B12 are essential during pregnancy, but you should only take this medicine if prescribed by your doctor. The dose may need to be adjusted.
A: No, this medicine does not cause weight gain. It is not a steroid and does not affect weight. In fact, it may improve metabolism in deficient individuals.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller. It is a nutritional supplement that helps correct vitamin deficiencies and supports nerve health. It may reduce nerve pain over time, but it is not a direct pain reliever. - Myth: This medicine can be taken by anyone for energy boost.
Fact: This medicine is meant for people with specific vitamin deficiencies or medical conditions. Taking it without a deficiency is unlikely to provide extra energy and may not be necessary. - Myth: This medicine is a steroid and can cause weight gain.
Fact: This medicine is not a steroid. It contains vitamins and does not cause weight gain. In fact, it may help improve metabolism in deficient individuals. - Myth: You can stop this medicine as soon as you feel better.
Fact: You should only stop this medicine when your doctor advises. Stopping too early may cause your symptoms to return or your deficiency to worsen. - Myth: This medicine has no side effects because it is a vitamin.
Fact: Even vitamins can cause side effects in some people. This medicine is generally safe, but mild side effects like nausea or stomach upset can occur. Serious side effects are rare.
🔄 Alternative Options
Generic Alternatives
- L-Methyl Folate + Methylcobalamin tablet
Brand Alternatives
- Athrovas HC Tablet