asthacold-ax tablet - Ambroxol (30mg) + Phenylephrine (5mg) medicine

Asthacold-ax Tablet: Comprehensive Medicine Guide

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🏭 Krishna Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 28, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 28, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe headache with blurred vision
  • Chest pain or palpitations
  • Difficulty breathing or swelling of face, lips, or throat
  • Blood in sputum or vomit
  • Severe abdominal pain
  • Decreased urine output or difficulty urinating
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is asthacold-ax tablet used for?

This medicine is a combination of Ambroxol and Phenylephrine used to relieve nasal and chest congestion associated with the common cold. Ambroxol thins mucus, while Phenylephrine reduces nasal swelling. It is usually taken two to three times daily for up to 7 days.

  • Generic Name: Ambroxol + Phenylephrine
  • Manufacturer: Krishna Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 asthacold-ax tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एम्ब्रोक्सोल और फेनाइलेफ्रिन का संयोजन है, जिसका उपयोग सर्दी-जुकाम से जुड़ी नाक और छाती की भीड़ को कम करने के लिए किया जाता है। एम्ब्रोक्सोल बलगम को पतला करता है, जबकि फेनाइलेफ्रिन नाक की सूजन को कम करता है। यह दवा आमतौर पर दिन में दो से तीन बार, अधिकतम 7 दिनों तक ली जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, पेट में असहजता, मुँह सूखना, सिरदर्द और घबराहट शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको तेज धड़कन, उच्च रक्तचाप, पेशाब में कठिनाई, या एलर्जी की प्रतिक्रिया हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। यदि आपको चक्कर आते हैं या नींद आती है, तो वाहन चलाने या मशीनरी चलाने से बचें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड की समस्या, या पेशाब में कठिनाई है, तो अपने डॉक्टर को बताएं। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 asthacold-ax tablet Uses & Benefits

[{"condition":"Nasal congestion due to common cold","description":"Phenylephrine reduces inflammation" class="semantic-link" title="Medicines for swelling">swelling of nasal passages, providing relief from stuffy nose.","evidence":"Well-established"},{"condition":"Productive cough with thick mucus","description":"Ambroxol helps thin and loosen mucus, making it easier to expel.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps relieve nasal congestion and promote drainage of sinus secretions.","evidence":"Moderate"},{"condition":"Allergic rhinitis","description":"Provides symptomatic relief of nasal congestion associated with allergies.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Bronchitis","description":"Sometimes used to help clear mucus in acute or chronic bronchitis.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally used to reduce nasal congestion and improve Eustachian tube function.","evidence":"Limited"}]

Primary treatment for: Common cold with nasal and chest congestion

Also treats: Allergic rhinitis, Sinusitis, Bronchitis

📋 Drug Information

Generic Name(s)Ambroxol + Phenylephrine
Brand NameAmicet Plus Tablet
ManufacturerKrishna Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Decongestant
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture. Do not use after the expiry date printed on the package.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day to help thin mucus.
3
Avoid alcohol while taking this medicine as it may increase drowsiness and cardiovascular effects.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Monitor your blood pressure if you have hypertension.
7
Avoid driving or operating machinery if you feel dizzy.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
✅
Chest congestion with productive cough
Ambroxol helps thin mucus.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Sore throat
This medicine does not directly treat sore throat.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmbroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Phenylephrine is also absorbed orally but undergoes extensive first-pass metabolism, resulting in reduced systemic bioavailability. Not established from the available information for specific absorption rates of this combination.
DistributionAmbroxol distributes widely into body tissues, including lung tissue, and crosses the blood-brain barrier and placental barrier. Phenylephrine distribution is not well characterized but is expected to distribute into extracellular fluids. Not established from the available information for specific volumes of distribution.
Protein BindingAmbroxol is approximately 90% bound to plasma proteins. Phenylephrine protein binding is not established from the available information.
MetabolismAmbroxol is metabolized in the liver primarily by conjugation to glucuronic acid and sulfate, forming inactive metabolites. Phenylephrine undergoes extensive first-pass metabolism in the gut wall and liver, primarily by monoamine oxidase and sulfotransferases.
Half-LifeAmbroxol elimination half-life is approximately 7 to 12 hours. Phenylephrine elimination half-life is approximately 2 to 3 hours. Not established from the available information for the combination product.
ExcretionAmbroxol and its metabolites are excreted primarily in the urine. Phenylephrine and its metabolites are also excreted mainly in the urine. Not established from the available information for specific excretion percentages.
BioavailabilityAmbroxol oral bioavailability is approximately 70 to 80 percent due to first-pass metabolism. Phenylephrine oral bioavailability is low, approximately 38 percent, due to extensive first-pass metabolism. Not established from the available information for the combination product.
Onset of ActionAmbroxol onset of action is typically within 30 to 60 minutes after oral administration. Phenylephrine onset of action is within 15 to 30 minutes. Not established from the available information for the combination product.
Peak Plasma TimeAmbroxol peak plasma concentration occurs approximately 1 to 3 hours after oral administration. Phenylephrine peak plasma concentration occurs approximately 1 to 2 hours after oral administration. Not established from the available information for the combination product.
Duration of ActionAmbroxol duration of action is approximately 6 to 12 hours. Phenylephrine duration of action is approximately 4 to 6 hours. Not established from the available information for the combination product.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Ambroxol is a mucolytic agent that increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production, thereby facilitating mucus clearance. Phenylephrine is a sympathomimetic amine that selectively stimulates alpha-1 adrenergic receptors on nasal blood vessels, causing vasoconstriction and reducing nasal mucosal swelling and congestion.

Mechanism Steps

1
Ambroxol increases serous secretion: Ambroxol stimulates the serous cells of the bronchial glands to produce more watery secretions, which helps thin thick mucus.
2
Ambroxol reduces mucus viscosity: By breaking down acidic mucopolysaccharide fibers, Ambroxol lowers the viscosity of mucus, making it easier to cough up.
3
Ambroxol enhances ciliary clearance: Ambroxol improves the beating action of cilia, helping to move loosened mucus out of the airways.
4
Phenylephrine binds to alpha-1 receptors: Phenylephrine selectively binds to alpha-1 adrenergic receptors located on vascular smooth muscle in the nasal mucosa.
5
Phenylephrine causes vasoconstriction: Activation of alpha-1 receptors leads to constriction of nasal blood vessels, reducing blood flow and mucosal swelling.
6
Reduced nasal congestion: The vasoconstriction decreases tissue edema and nasal blockage, resulting in improved breathing.

💡 How to Take asthacold-ax tablet

Strength: Each tablet contains Ambroxol 30 mg and Phenylephrine 5 mg.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food or milk to reduce stomach upset.
4Follow the prescribed dose and frequency exactly.
5Do not exceed the recommended dose or duration of use.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally two to three times daily, or as directed by your physician. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. The maximum daily dose should not exceed three tablets in 24 hours. Use for the shortest duration necessary to relieve symptoms.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of Phenylephrine, particularly on blood pressure and heart rate. Use with caution and monitor vital signs. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for appropriate dosing.
Renal ImpairmentNot established from the available information. Use with caution in patients with renal impairment. Dose adjustment may be required. Consult your doctor.
Hepatic ImpairmentNot established from the available information. Use with caution in patients with hepatic impairment. Dose adjustment may be required. Consult your doctor.
Maximum Daily DoseThe maximum daily dose of this medicine is three tablets in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and insomnia.
Tyramine-rich foods
Consume in moderation
May increase blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of asthacold-ax tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food to reduce stomach upset. If nausea persists, consult your doctor.
Dry mouth (Common (1-10%))
Sip water frequently. Chew sugar-free gum if needed. Consult doctor if severe.
Headache (Common (1-10%))
Rest and stay hydrated. Use a mild pain reliever if necessary, but consult your doctor first.
Nervousness (Common (1-10%))
Avoid caffeine and get adequate rest. If it interferes with daily activities, consult your doctor.
Stomach discomfort (Common (1-10%))
Take with a meal or snack. If it continues, speak to your doctor.

🚨 Serious Side Effects

Severe hypertension (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, or chest pain.
Palpitations or irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you notice a rapid or pounding heartbeat.
Difficulty urinating (Rare (<0.1%))
Consult your doctor if you have trouble passing urine or experience pain while urinating.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Skin rash or itching
Stop the medicine and consult your doctor if a rash develops.
Tremors
Report to your doctor if you experience involuntary shaking.
Anxiety or restlessness
Consult your doctor if these symptoms are bothersome.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
Digoxin Moderate
Ergot alkaloids Moderate
Oxytocin Moderate
Antacids Minor
Caffeine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • Digoxin
  • Ergot alkaloids
  • Oxytocin

🍷 Alcohol Interaction

Alcohol may increase drowsiness and cardiovascular effects of this medicine. Avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Ambroxol, Phenylephrine, or any component of the formulation","Severe hypertension","Severe coronary artery disease","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs","Patients with pheochromocytoma","Patients with narrow-angle glaucoma","Patients with urinary retention"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disease, including hypertension and arrhythmias.","Use with caution in patients with diabetes mellitus, thyroid dysfunction, or prostatic hypertrophy.","May cause dizziness; avoid driving or operating machinery until you know how this medicine affects you.","Do not exceed the recommended dose or duration of use without medical advice.","Consult a doctor if symptoms persist or worsen after 7 days of use.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. It is not known whether Ambroxol or Phenylephrine pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe hypertension, palpitations, nausea, vomiting, and restlessness. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of use. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, or difficulty urinating. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children. Avoid alcohol while taking this medicine as it may increase drowsiness and cardiovascular effects.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of Phenylephrine, such as increased blood pressure and palpitations. Use with caution and monitor vital signs. Dose adjustment may be necessary based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant or are pregnant. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks before prescribing.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially if you have had recent nasal or sinus surgery. Phenylephrine may affect blood pressure and healing.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as Phenylephrine can interact with certain local anesthetics and affect blood pressure. Your dentist may adjust the anesthetic used.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to keep airways moist.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to support recovery.
🧘
Practice good hand hygiene to prevent spread of infection.
🌞
Use saline nasal rinses to help clear nasal passages.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy, have palpitations, or are short of breath. Light activity like walking is generally safe. Consult your doctor before resuming intense exercise.

🥗 Diet Recommendations

Drink warm fluids like soups and herbal teas.
Include vitamin C-rich fruits and vegetables.
Avoid cold and sugary drinks that can thicken mucus.
Limit caffeine intake to reduce nervousness.
Eat a balanced diet to support immune function.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause nervousness, which can affect concentration. Take it as prescribed and adjust work activities accordingly.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as severe headache, palpitations, or difficulty breathing. Do not stop abruptly if you have been taking it for a prolonged period without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of Phenylephrine can lead to rebound congestion and increased blood pressure. Ambroxol is generally well-tolerated but should not be used beyond 7 days without medical advice. Regular monitoring of blood pressure and heart rate is advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Steam inhalation

Can help loosen mucus and relieve congestion.

Evidence: Moderate
Humidifier use

Adds moisture to the air, soothing irritated airways.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Consult your doctor regarding vaccination timing if you are currently taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep a list of your medications with you.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with common cold and severe nasal congestion
He was prescribed this medicine for 5 days. He took it with food as advised. His nasal congestion improved significantly within 2 days, and chest congestion cleared by day 4. He experienced mild dry mouth, which resolved after finishing the course.
💡 Lesson: Taking this medicine with food and staying hydrated helps manage side effects and improves tolerability.
👤 A 50-year-old woman with hypertension and sinusitis
She was prescribed this medicine with caution due to her high blood pressure. Her doctor monitored her blood pressure regularly. She experienced mild nervousness but no significant rise in blood pressure. Symptoms improved over 5 days.
💡 Lesson: Patients with hypertension should use this medicine under medical supervision and monitor blood pressure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving nasal congestion within 30 minutes to 1 hour. Chest congestion may improve over a few days of regular use.

Q: Can I take this medicine with food?

A: Yes, taking it with food helps reduce stomach upset.

Q: Is it safe to take with other cold medicines?

A: Consult your doctor before combining with other cold medicines to avoid overlapping ingredients and potential interactions.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for asthacold-ax tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only provides symptomatic relief; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: This medicine should not be used for more than 7 days without medical advice due to potential side effects.
  • Myth: More tablets mean faster relief.
    Fact: Taking more than the recommended dose can lead to serious side effects and does not speed up recovery.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Phenylephrine tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ambroxol 30 mg + Phenylephrine 5 mg","uses":"Nasal and chest congestion","notes":"Combination of mucolytic and decongestant."},{"medicine":"Ambroxol + Guaifenesin","composition":"Ambroxol + Guaifenesin","uses":"Productive cough","notes":"Both are mucolytics; no decongestant."},{"medicine":"Phenylephrine + Chlorpheniramine","composition":"Phenylephrine + Chlorpheniramine","uses":"Allergic rhinitis","notes":"Decongestant plus antihistamine."}]

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