Asmaphylin M 231mg/69mg/10mg Tablet SR: Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe palpitations or irregular heartbeat
- Seizures or convulsions
- Blood in vomit or black stools
- Severe abdominal pain
- Difficulty breathing or swelling of face, lips, or throat
- Fainting or loss of consciousness
- Persistent vomiting
If experiencing severe symptoms, call emergency services immediately.
What is asmaphylin m 231mg/69mg/10mg tablet sr used for?
This medicine is a combination of etofylline and theophylline, used to treat bronchospasm in asthma and COPD. It works by relaxing airway muscles to improve breathing. It is not for sudden attacks.
- Generic Name: Etofylline + Theophylline
- Manufacturer: ICI Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 asmaphylin m 231mg/69mg/10mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा एटोफाइलिन और थियोफाइलिन का संयोजन है, जिसका उपयोग अस्थमा और सीओपीडी जैसी श्वसन संबंधी बीमारियों में सांस लेने में आसानी के लिए किया जाता है। यह वायुमार्ग की मांसपेशियों को आराम देकर घरघराहट और सांस की तकलीफ को कम करती है। यह दवा तुरंत अस्थमा अटैक के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, सिरदर्द, बेचैनी और दिल की धड़कन बढ़ना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें अनियमित दिल की धड़कन, दौरे और गंभीर एलर्जी शामिल हो सकते हैं। यदि आपको धड़कन, बेहोशी या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को चबाएं नहीं, पूरा निगल लें। शराब और कैफीन का सेवन न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। बिना सलाह के दवा शुरू या बंद न करें।
💊 asmaphylin m 231mg/69mg/10mg tablet sr Uses & Benefits
[{"condition":"Bronchial asthma","description":"Used as maintenance therapy to prevent wheezing and shortness of breath in chronic asthma.","evidence":"Established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Helps relax airway smooth muscle and improve airflow in patients with COPD.","evidence":"Established"},{"condition":"Bronchospasm associated with chronic bronchitis","description":"Provides symptomatic relief of bronchospasm in chronic bronchitis.","evidence":"Established"}]
Off-label uses: [{"condition":"Apnea of prematurity","description":"Methylxanthines like theophylline have been used off-label in premature infants, but this combination is not standard for this use.","evidence":"Limited"}]
Primary treatment for: Bronchial asthma
Also treats: Chronic obstructive pulmonary disease (COPD), Chronic bronchitis
📋 Drug Information
| Generic Name(s) | Etofylline + Theophylline |
| Brand Name | Asmaphylin M 231mg/69mg/10mg Tablet SR |
| Manufacturer | ICI Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Xanthine bronchodilator |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Etofylline and theophylline are methylxanthine derivatives that relax bronchial smooth muscle. They inhibit phosphodiesterase enzymes, leading to increased cyclic AMP levels in airway smooth muscle cells, which causes bronchodilation. They also block adenosine receptors, which contributes to both bronchodilation and central nervous system stimulation. Additionally, they improve diaphragmatic contractility and mucociliary clearance.
Mechanism Steps
💡 How to Take asmaphylin m 231mg/69mg/10mg tablet sr
Strength: Each sustained-release tablet contains etofylline 231 mg and theophylline 69 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, or as directed by your physician. The exact dose and frequency depend on the severity of your condition, your response to treatment, and other factors such as age, liver function, and concomitant medications. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of theophylline and are at higher risk of toxicity. Dose reduction may be necessary. Close monitoring of serum levels and clinical response is recommended. |
| Renal Impairment | Dose adjustment may be required in patients with severe renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Dose reduction is recommended in patients with liver disease, as theophylline clearance is reduced. Close monitoring is advised. |
| Maximum Daily Dose | The maximum daily dose should not exceed the equivalent of 900 mg of theophylline per day, but individual limits are set by the prescribing clinician based on serum levels and clinical response. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of asmaphylin m 231mg/69mg/10mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Erythromycin | Major | |
| Cimetidine | Major | |
| Propranolol | Major | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate | |
| Oral contraceptives | Moderate | |
| Furosemide | Minor | |
| Corticosteroids | Minor | |
| Alcohol | Moderate |
🚨 Major Interactions
- Ciprofloxacin
- Erythromycin
- Cimetidine
- Propranolol
⚡ Moderate Interactions
- Phenytoin
- Rifampicin
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the central nervous system side effects of theophylline, such as dizziness and drowsiness, and may also affect liver metabolism of the drug. It can also worsen dehydration and increase heart rate.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to etofylline, theophylline, or other methylxanthines","Active peptic ulcer disease","Uncontrolled cardiac arrhythmias","Acute porphyria","Children under 12 years of age (unless specifically prescribed by a pediatrician)"]
⚠️ Warnings & Precautions
["Use with caution in patients with heart disease, hypertension, or arrhythmias.","Use with caution in patients with liver disease, as dose reduction may be needed.","Use with caution in patients with renal impairment.","Avoid in patients with seizure disorders, as methylxanthines can lower seizure threshold.","Avoid alcohol and caffeine during treatment.","Do not crush or chew sustained-release tablets; swallow whole.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Do not use for acute bronchospasm attacks; this is not a rescue medication."]
🤱 Lactation Safety
Theophylline is excreted in breast milk and may cause irritability or insomnia in the nursing infant. Breastfeeding is not recommended while taking this medicine unless the benefits outweigh the risks. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe nausea, vomiting, restlessness, palpitations, seizures, and cardiac arrhythmias. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, antiarrhythmics, and management of seizures. Hemodialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush or chew the tablet; swallow it whole with a glass of water. Avoid alcohol and excessive caffeine while taking this medicine because they can increase nervousness and heart rate. Inform your doctor about all other medicines you take, especially antibiotics like ciprofloxacin, erythromycin, and medicines for heart conditions. Do not start or stop this medicine without consulting your doctor. If you miss a dose, follow the missed dose instructions provided. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to theophylline toxicity due to reduced clearance. Lower doses and close monitoring are recommended.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy. This medicine should be used during pregnancy only if clearly needed. Your doctor may adjust the dose or switch to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rhythm. Close monitoring during surgery is advised.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or increase heart rate during dental procedures. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid strenuous activity if you have severe breathing difficulty. Consult your doctor before starting any exercise program. Stop and rest if you feel dizzy or short of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or restlessness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most desk jobs.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor will decide if and when to stop.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of serum theophylline levels to avoid toxicity. It may cause tolerance and increased side effects over time. Periodic assessment of liver and kidney function is advised. Do not stop suddenly without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be used as controller therapy for asthma.
Evidence: Well-establishedUsed in combination with inhaled steroids for asthma and COPD.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Patients with chronic respiratory diseases should receive annual influenza and pneumococcal vaccinations as per guidelines. This medicine does not interact with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 1 hour, but full benefits for chronic conditions may take several days to weeks.
A: Yes, you can take it with or without food, but be consistent. Taking with food may reduce stomach upset.
A: Avoid alcohol, caffeine, and smoking. Also avoid taking other medicines without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for asmaphylin m 231mg/69mg/10mg tablet sr
View AllAlternative brands with exact same active ingredient:
-
dericip 231mg/69mg tabletCipla Ltd ₹3.69 95.9% CHEAPER
-
etosal tabletIndica Laboratories Pvt Ltd ₹4.43 95.1% CHEAPER
-
dericip retard 300 tablet prCipla Ltd ₹16.25 81.9% CHEAPER
-
dericip od 231mg/69mg tabletCipla Ltd ₹32.49 63.9% CHEAPER
-
deriphyllin retard 300 tablet prZydus Cadila ₹64.43 28.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used as a rescue inhaler during an asthma attack.
Fact: This medicine is for maintenance therapy and is not effective for immediate relief of acute bronchospasm. Use a rescue inhaler as prescribed. - Myth: More of this medicine will work faster.
Fact: Taking more than the prescribed dose can lead to serious toxicity. Always follow your doctor's instructions.
🔄 Alternative Options
Generic Alternatives
- Etofylline + Theophylline sustained-release tablets
Brand Alternatives
- Asmaphylin M 231mg/69mg/10mg Tablet SR