asmanixt-fb 400 inhaler - Formoterol (6mcg) + Budesonide (400mcg) medicine

Asmanixt-FB 400 Inhaler - Uses, Price, Side Effects

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๐Ÿญ Chemo Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is asmanixt-fb 400 inhaler used for?

Asmanixt-FB 400 Inhaler is a combination of Formoterol (a long-acting bronchodilator) and Budesonide (a corticosteroid) used for the maintenance treatment of asthma and COPD. It works by relaxing airway muscles and reducing inflammation, helping to prevent breathing difficulties and improve lung function.

  • Generic Name: Formoterol + Budesonide
  • Manufacturer: Chemo Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š asmanixt-fb 400 inhaler Uses & Benefits

Maintenance treatment of asthma and COPD

Off-label uses: Acute bronchospasm (not recommended)

๐Ÿ“‹ Drug Information

Generic Name(s)Formoterol + Budesonide
Brand NameAirtec FB 400 Instacap
ManufacturerChemo Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassCombined long-acting beta2-agonist and inhaled corticosteroid
Route of AdministrationInhalation (oral)
StorageStore at 25ยฐC (77ยฐF); excursions permitted to 15-30ยฐC (59-86ยฐF)
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the lungs after inhalation
DistributionDistributes into lungs and systemic circulation
Protein BindingFormoterol: 61-64%; Budesonide: 85-90%
MetabolismFormoterol: Hepatic via glucuronidation and O-demethylation; Budesonide: Hepatic via CYP3A4
Half-LifeFormoterol: 10 hours; Budesonide: 2-3 hours
ExcretionFormoterol: Renal (60%) and fecal (40%); Budesonide: Renal (60%) and fecal (40%)
BioavailabilityFormoterol: ~50%; Budesonide: ~11%
Onset of ActionFormoterol: 1-3 minutes; Budesonide: 24 hours
Peak Plasma TimeFormoterol: 0.5-1 hour; Budesonide: 0.5-1 hour
Duration of ActionFormoterol: 12 hours; Budesonide: 12-24 hours

How It Works

Formoterol stimulates beta2-adrenergic receptors causing bronchodilation; Budesonide reduces airway inflammation by inhibiting inflammatory mediators

Mechanism Steps

1Formoterol binds to beta2-adrenergic receptors on airway smooth muscle
2Activates adenylate cyclase, increasing cAMP
3Relaxes bronchial smooth muscle (bronchodilation)

๐Ÿ’ก How to Take asmanixt-fb 400 inhaler

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of asmanixt-fb 400 inhaler

โœ… Common Side Effects

  • Headache
  • Throat irritation
  • Cough
  • Hoarseness
  • Tremor

๐Ÿšจ Serious Side Effects

  • Paradoxical bronchospasm
  • Cardiac arrhythmias
  • Hypokalemia
  • Adrenal insufficiency

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Cushing's syndrome
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Moderate Increased risk of systemic corticosteroid effects
Diuretics Moderate Hypokalemia risk
Beta-blockers Moderate Antagonism of bronchodilator effect

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • Beta-blockers (non-selective)

โšก Moderate Interactions

  • Diuretics (potassium-depleting)
  • MAOIs
  • Tricyclic antidepressants

โ„น๏ธ Minor Interactions

  • Xanthine derivatives
  • Other beta-agonists

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase budesonide levels

๐Ÿท Alcohol Interaction

No significant interaction

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to any component, status asthmaticus

๐Ÿ“Š Monitoring Parameters

Lung function, symptom control, heart rate, potassium levels

๐Ÿคฑ Lactation Safety

Caution; excreted in breast milk

๐Ÿ’Š Overdose Management

Supportive care; monitor cardiac function and potassium levels

โฐ Missed Dose

Take as soon as remembered; skip if close to next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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